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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10227 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Development of Extraocular Muscles Require Early Signals From Periocular Neural Crest and the Developing Eye

Authors:
Bohnsack BL, Gallina D, Thompson H, Kasprick DS, Lucarelli MJ, Dootz G, Nelson C, McGonnell IM, Kahana A
Citation:
Arch Ophthalmol. 2011 Apr 11. [Epub ahead of print]
Abstract:
Objectives To identify and explain morphologic changes of the extraocular muscles (EOMs) in anophthalmic patients. Methods...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bohnsack BL, Gallina D, Thompson H, Kasprick DS, Lucarelli MJ, Dootz G, Nelson C, McGonnell IM, Kahana A. Development of Extraocular Muscles Require Early Signals From Periocular Neural Crest and the Developing Eye. Arch Ophthalmol. 2011 Apr 11. [Epub ahead of print].

Development of hypothalamic serotoninergic neurons requires Fgf signalling via the ETS-domain transcription factor Etv5b

Authors:
Bosco A, Bureau C, Affaticati P, Gaspar P, Bally-Cuif L, Lillesaar C
Citation:
Development. 2013;140:372-384. doi:10.1242/dev.089094
Abstract:
Serotonin is a monoamine neurotransmitter that is involved in numerous physiological functions and its dysregulation is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bosco A, Bureau C, Affaticati P, Gaspar P, Bally-Cuif L, Lillesaar C. Development of hypothalamic serotoninergic neurons requires Fgf signalling via the ETS-domain transcription factor Etv5b. Development. 2013;140:372-384. doi:10.1242/dev.089094 .

Differential roles of p39(Mos)-Xp42(Mpk1) cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes

Authors:
Bodart JF, Baert FY, Sellier C, Duesbery NS, Flament S, Vilain JP
Citation:
Dev Biol. 2005 Jul 15;283(2):373-83.
Abstract:
Fully-grown G2-arrested Xenopus oocytes resume meiosis upon hormonal stimulation. Resumption of meiosis is characterized by...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Bodart JF, Baert FY, Sellier C, Duesbery NS, Flament S, Vilain JP. Differential roles of p39(Mos)-Xp42(Mpk1) cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes. Dev Biol. 2005 Jul 15;283(2):373-83..

Divergent polarization mechanisms during vertebrate epithelial development mediated by the Crumbs complex protein Nagie oko

Authors:
Bit-Avragim N, Hellwig N, Rudolph F, Munson C, Stainier DY, Abdelilah-Seyfried S
Citation:
J Cell Sci. 2008 Aug 1;121(Pt 15):2503-10. Epub 2008 Jul 15
Abstract:
The zebrafish MAGUK protein Nagie oko is a member of the evolutionarily conserved Crumbs protein complex and functions as a...
Organism or Cell Type:
zebrafish
Citation Extract:
Bit-Avragim N, Hellwig N, Rudolph F, Munson C, Stainier DY, Abdelilah-Seyfried S. Divergent polarization mechanisms during vertebrate epithelial development mediated by the Crumbs complex protein Nagie oko. J Cell Sci. 2008 Aug 1;121(Pt 15):2503-10. Epub 2008 Jul 15.

DNA damage response and Ku80 function in the vertebrate embryo

Authors:
Bladen CL, Lam WK, Dynan WS, Kozlowski DJ
Citation:
Nucleic Acids Res. 2005 May 24;33(9):3002-10. Print 2005
Abstract:
Cellular responses to DNA damage reflect the dynamic integration of cell cycle control, cell-cell interactions and tissue-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bladen CL, Lam WK, Dynan WS, Kozlowski DJ. DNA damage response and Ku80 function in the vertebrate embryo. Nucleic Acids Res. 2005 May 24;33(9):3002-10. Print 2005.

Domain-specific regulation of foxP2 CNS expression by lef1

Authors:
Bonkowsky JL, Wang X, Fujimoto E, Lee JE, Chien CB, Dorsky RI
Citation:
BMC Dev Biol. 2008 Oct 24;8:103
Abstract:
BACKGROUND: FOXP2 is a forkhead transcription factor critical for normal development of language in humans, but little is known...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bonkowsky JL, Wang X, Fujimoto E, Lee JE, Chien CB, Dorsky RI. Domain-specific regulation of foxP2 CNS expression by lef1. BMC Dev Biol. 2008 Oct 24;8:103.

Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death

Authors:
Bota DA, Ngo JK, Davies KJ
Citation:
Free Radic Biol Med. 2005 Mar 1;38(5):665-77
Abstract:
Lon now emerges as a major regulator of multiple mitochondrial functions in human beings. Lon catalyzes the degradation of...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: human fibroblasts WI-38 VA-13
Citation Extract:
Bota DA, Ngo JK, Davies KJ. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic Biol Med. 2005 Mar 1;38(5):665-77.

Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication

Authors:
Blachon S, Gopalakrishnan J, Omori Y, Polyanovsky A, Church A, Nicastro D, Malicki J, Avidor-Reiss T
Citation:
Genetics. 2008 Dec;180(4):2081-94. Epub 2008 Oct 14
Abstract:
The centriole is the core structure of centrosome and cilium. Failure to restrict centriole duplication to once per cell cycle...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blachon S, Gopalakrishnan J, Omori Y, Polyanovsky A, Church A, Nicastro D, Malicki J, Avidor-Reiss T. Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication. Genetics. 2008 Dec;180(4):2081-94. Epub 2008 Oct 14.

Efficient mapping and cloning of mutations in zebrafish by low-coverage whole-genome sequencing

Authors:
Bowen ME, Henke K, Siegfried KR, Warman ML, Harris MP
Citation:
Genetics. 2012 Mar;190(3):1017-24. doi: 10.1534/genetics.111.136069. Epub 2011 Dec 14
Abstract:
The generation and analysis of mutants in zebrafish has been instrumental in defining the genetic regulation of vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bowen ME, Henke K, Siegfried KR, Warman ML, Harris MP. Efficient mapping and cloning of mutations in zebrafish by low-coverage whole-genome sequencing. Genetics. 2012 Mar;190(3):1017-24. doi: 10.1534/genetics.111.136069. Epub 2011 Dec 14.

Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus

Authors:
Beunders G, Voorhoeve E, Golzio C, Pardo LM, Rosenfeld JA, Talkowski ME, Simonic I, Lionel AC, Vergult S, Pyatt RE, van de Kamp J, Nieuwint A, Weiss MM, Rizzu P, Verwer LE, van Spaendonk RM, Shen Y, Wu BL, Yu T, Yu Y, Chiang C, Gusella JF, Lindgren AM, Morton CC, van Binsbergen E, Bulk S, van Rossem E, Vanakker O, Armstrong R, Park SM, Greenhalgh L, Maye U, Neill NJ, Abbott KM, Sell S, Ladda R, Farber DM, Bader PI, Cushing T, Drautz JM, Konczal L, Nash P, de Los Reyes E, Carter MT, Hopkins E, Marshall CR, Osborne LR, Gripp KW, Thrush DL, Hashimoto S, Gastier-Foster JM, Astbury C, Ylstra B, Meijers-Heijboer H, Posthuma D, Menten B, Mortier G, Scherer SW, Eichler EE, Girirajan S, Katsanis N, Groffen AJ, Sistermans EA.
Citation:
Am J Hum Genet. 2013 Feb 7;92(2):210-20. doi: 10.1016/j.ajhg.2012.12.011. Epub 2013 Jan 17.
Abstract:
Genomic rearrangements involving AUTS2 (7q11.22) are associated with autism and intellectual disability (ID), although evidence...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Beunders G, Voorhoeve E, Golzio C, Pardo LM, Rosenfeld JA, Talkowski ME, Simonic I, Lionel AC, Vergult S, Pyatt RE, van de Kamp J, Nieuwint A, Weiss MM, Rizzu P, Verwer LE, van Spaendonk RM, Shen Y, Wu BL, Yu T, Yu Y, Chiang C, Gusella JF, Lindgren AM, Morton CC, van Binsbergen E, Bulk S, van Rossem E, Vanakker O, Armstrong R, Park SM, Greenhalgh L, Maye U, Neill NJ, Abbott KM, Sell S, Ladda R, Farber DM, Bader PI, Cushing T, Drautz JM, Konczal L, Nash P, de Los Reyes E, Carter MT, Hopkins E, Marshall CR, Osborne LR, Gripp KW, Thrush DL, Hashimoto S, Gastier-Foster JM, Astbury C, Ylstra B, Meijers-Heijboer H, Posthuma D, Menten B, Mortier G, Scherer SW, Eichler EE, Girirajan S, Katsanis N, Groffen AJ, Sistermans EA. . Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus. Am J Hum Genet. 2013 Feb 7;92(2):210-20. doi: 10.1016/j.ajhg.2012.12.011. Epub 2013 Jan 17..

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