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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

Authors:
Kinali M, Arechavala-Gomeza V, Feng L, Cirak S, Hunt D, Adkin C, Guglieri M, Ashton E, Abbs S, Nihoyannopoulos P, Garralda ME, Rutherford M, McCulley C, Popplewell L, Graham IR, Dickson G, Wood MJ, Wells DJ, Wilton SD, Kole R, Straub V, Bushby K, Sewry C, Morgan JE, Muntoni F
Citation:
Lancet Neurol. 2009 Oct;8(10):918-28. Epub 2009 Aug 25
Epub:
Not Epub
Abstract:
BACKGROUND: <omitted, database space constraint> METHODS: We did a single-blind, placebo-controlled, dose-escalation...
Delivery Method:
Injection
Organism or Cell Type:
human
Citation Extract:
Kinali M, Arechavala-Gomeza V, Feng L, Cirak S, Hunt D, Adkin C, Guglieri M, Ashton E, Abbs S, Nihoyannopoulos P, Garralda ME, Rutherford M, McCulley C, Popplewell L, Graham IR, Dickson G, Wood MJ, Wells DJ, Wilton SD, Kole R, Straub V, Bushby K, Sewry C, Morgan JE, Muntoni F. Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study. Lancet Neurol. 2009 Oct;8(10):918-28. Epub 2009 Aug 25.

Lrrc10 is required for early heart development and function in zebrafish

Authors:
Kim KH, Antkiewicz DS, Yan L, Eliceir KW, Heideman W, Peterson RE, Lee Y
Citation:
Dev Biol. 2007 Aug 15;308(2):494-506. Epub 2007 Jun 13
Epub:
Not Epub
Abstract:
Leucine-rich Repeat Containing protein 10 (LRRC10) has recently been identified as a cardiac-specific factor in mice. However,...
Organism or Cell Type:
zebrafish
Citation Extract:
Kim KH, Antkiewicz DS, Yan L, Eliceir KW, Heideman W, Peterson RE, Lee Y. Lrrc10 is required for early heart development and function in zebrafish. Dev Biol. 2007 Aug 15;308(2):494-506. Epub 2007 Jun 13.

Molecular and Functional Analyses of Aspolin, a Fish-Specific Protein Extremely Rich in Aspartic Acid

Authors:
Kinoshita S, Katsumi E, Yamamoto H, Takeuchi K, Watabe S
Citation:
Mar Biotechnol (NY). 2011 Jun;13(3):517-26. doi: 10.1007/s10126-010-9322-y. Epub 2010 Sep 29.
Epub:
Not Epub
Abstract:
Aspolin is a muscular protein having unique structural characteristics where the most part of its primary structure is occupied...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kinoshita S, Katsumi E, Yamamoto H, Takeuchi K, Watabe S. Molecular and Functional Analyses of Aspolin, a Fish-Specific Protein Extremely Rich in Aspartic Acid. Mar Biotechnol (NY). 2011 Jun;13(3):517-26. doi: 10.1007/s10126-010-9322-y. Epub 2010 Sep 29..

Molecular cloning and characterization of human GIPC2, a novel gene homologous to human GIPC1 and Xenopus Kermit

Authors:
Kirikoshi H, Katoh M
Citation:
Int J Oncol. 2002 Mar;20(3):571-6
Epub:
Not Epub
Abstract:
PDZ-domain protein GIPC1/GIPC interacts with GTPase-activating protein RGS-GAIP, TGFbeta type III receptor, and integrin...
Citation Extract:
Kirikoshi H, Katoh M. Molecular cloning and characterization of human GIPC2, a novel gene homologous to human GIPC1 and Xenopus Kermit. Int J Oncol. 2002 Mar;20(3):571-6.

Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry

Authors:
Kim S, Zaghloul NA, Bubenshchikova E, Oh EC, Rankin S, Katsanis N, Obara T, Tsiokas L
Citation:
Nat Cell Biol. 2011 Apr;13(4):351-60. Epub 2011 Mar 13
Epub:
Not Epub
Abstract:
The primary cilium is an antenna-like organelle that is dynamically regulated during the cell cycle. Ciliogenesis is initiated...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim S, Zaghloul NA, Bubenshchikova E, Oh EC, Rankin S, Katsanis N, Obara T, Tsiokas L. Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry. Nat Cell Biol. 2011 Apr;13(4):351-60. Epub 2011 Mar 13.

Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin

Authors:
Kim SW, Park JI, Spring CM, Sater AK, Ji H, Otchere AA, Daniel JM, McCrea PD
Citation:
Nat Cell Biol. 2004 Dec;6(12):1212-20.
Epub:
Not Epub
Abstract:
Gastrulation movements are critical for establishing the three principal germ layers and the basic architecture of vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim SW, Park JI, Spring CM, Sater AK, Ji H, Otchere AA, Daniel JM, McCrea PD. Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin. Nat Cell Biol. 2004 Dec;6(12):1212-20..

Perspectives on antisense therapy for the prevention of restenosis

Authors:
Kipshidze N, Moses J, Shankar LR, Leon M
Citation:
Curr Opin Mol Ther 2001 Jun;3(3):265-77
Epub:
Not Epub
Abstract:
One of the potential clinical applications of antisense therapy is the prevention or treatment of restenosis following coronary...
Citation Extract:
Kipshidze N, Moses J, Shankar LR, Leon M. Perspectives on antisense therapy for the prevention of restenosis. Curr Opin Mol Ther 2001 Jun;3(3):265-77.

PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements

Authors:
Kinoshita N, Iioka H, Miyakoshi A, Ueno N
Citation:
Genes Dev. 2003 Jul 1;17(13):1663-76
Epub:
Not Epub
Abstract:
Protein kinase C (PKC) has been implicated in the Wnt signaling pathway; however, its molecular role is poorly understood. We...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kinoshita N, Iioka H, Miyakoshi A, Ueno N. PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements. Genes Dev. 2003 Jul 1;17(13):1663-76.

Planar cell polarity acts through septins to control collective cell movement and ciliogenesis

Authors:
Kim SK, Shindo A, Park TJ, Oh EC, Ghosh S, Gray RS, Lewis RA, Johnson CA, Attie-Bittach T, Katsanis N, Wallingford JB
Citation:
Science. 2010 Sep 10;329(5997):1337-40. Epub 2010 Jul 29
Epub:
Not Epub
Abstract:
The planar cell polarity (PCP) signaling pathway governs collective cell movements during vertebrate embryogenesis, and certain...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim SK, Shindo A, Park TJ, Oh EC, Ghosh S, Gray RS, Lewis RA, Johnson CA, Attie-Bittach T, Katsanis N, Wallingford JB. Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Science. 2010 Sep 10;329(5997):1337-40. Epub 2010 Jul 29.

Rab11 regulates planar polarity and migratory behavior of multiciliated cells in xenopus embryonic epidermis

Authors:
Kim K, Lake BB, Haremaki T, Weinstein DC, Sokol SY
Citation:
Dev Dyn. 2012 Sep;241(9):1385-95. doi: 10.1002/dvdy.23826. Epub 2012 Jul 16.
Epub:
Not Epub
Abstract:
BACKGROUND: Xenopus embryonic skin is composed of the superficial layer with defined apicobasal polarity and the inner layer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim K, Lake BB, Haremaki T, Weinstein DC, Sokol SY. Rab11 regulates planar polarity and migratory behavior of multiciliated cells in xenopus embryonic epidermis. Dev Dyn. 2012 Sep;241(9):1385-95. doi: 10.1002/dvdy.23826. Epub 2012 Jul 16..

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