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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

Authors:
Korac J, Schaeffer V, Kovacevic I, Clement AM, Jungblut B, Behl C, Terzic J, Dikic I
Citation:
J Cell Sci. 2012;[Advance Online Pub] doi:10.1242/jcs.114926
Epub:
Not Epub
Abstract:
Aggregation of misfolded proteins and the associated loss of neurons are considered as a hallmark of numerous neurodegenerative...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Korac J, Schaeffer V, Kovacevic I, Clement AM, Jungblut B, Behl C, Terzic J, Dikic I. Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates. J Cell Sci. 2012;[Advance Online Pub] doi:10.1242/jcs.114926.

Ultrasound-enhanced delivery of Morpholino with Bubble liposomes ameliorates the myotonia of myotonic dystrophy model mice

Authors:
Koebis M, Kiyatake T, Yamaura H, Nagano K, Higashihara M, Sonoo M, Hayashi Y, Negishi Y, Endo-Takahashi Y, Yanagihara D, Matsuda R, Takahashi MP, Nishino I, Ishiura S
Citation:
Sci Rep. 2013 Jul 22;3:2242. doi: 10.1038/srep02242.
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligonucleotide (PMO)-mediated control of the alternative splicing of the chloride channel 1 (...
Delivery Method:
liposomes, bubble
Organism or Cell Type:
mice, HSA(LR)
Citation Extract:
Koebis M, Kiyatake T, Yamaura H, Nagano K, Higashihara M, Sonoo M, Hayashi Y, Negishi Y, Endo-Takahashi Y, Yanagihara D, Matsuda R, Takahashi MP, Nishino I, Ishiura S. Ultrasound-enhanced delivery of Morpholino with Bubble liposomes ameliorates the myotonia of myotonic dystrophy model mice. Sci Rep. 2013 Jul 22;3:2242. doi: 10.1038/srep02242..

Wnt-11 and Fz7 reduce cell adhesion in convergent extension by sequestration of PAPC and C-cadherin

Authors:
Kraft B, Berger CD, Wallkamm V, Steinbeisser H, Wedlich D
Citation:
J Cell Biol. 2012 Aug 20;198(4):695-709. doi: 10.1083/jcb.201110076
Epub:
Not Epub
Abstract:
Wnt-11/planar cell polarity signaling polarizes mesodermal cells undergoing convergent extension during Xenopus laevis...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kraft B, Berger CD, Wallkamm V, Steinbeisser H, Wedlich D. Wnt-11 and Fz7 reduce cell adhesion in convergent extension by sequestration of PAPC and C-cadherin. J Cell Biol. 2012 Aug 20;198(4):695-709. doi: 10.1083/jcb.201110076.

Zebrafish gene knockdowns imply roles for human YWHAG in infantile spasms and cardiomegaly

Authors:
Komoike Y, Fujii K, Nishimura A, Hiraki Y, Hayashidani M, Shimojima K, Nishizawa T, Higashi K, Yasukawa K, Saitsu H, Miyake N, Mizuguchi T, Matsumoto N, Osawa M, Kohno Y, Higashinakagawa T, Yamamoto T
Citation:
Genesis. 2010 Feb 9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Williams-Beuren syndrome (WBS) is a neurodevelopmental disorder presenting with an elfin-like face, supravalvular aortic...
Organism or Cell Type:
zebrafish
Citation Extract:
Komoike Y, Fujii K, Nishimura A, Hiraki Y, Hayashidani M, Shimojima K, Nishizawa T, Higashi K, Yasukawa K, Saitsu H, Miyake N, Mizuguchi T, Matsumoto N, Osawa M, Kohno Y, Higashinakagawa T, Yamamoto T. Zebrafish gene knockdowns imply roles for human YWHAG in infantile spasms and cardiomegaly. Genesis. 2010 Feb 9. [Epub ahead of print].

Zebrafish Mir antagonizes Frizzled 7-induced gastrulation defects

Authors:
Knowlton MN, Kelly GM
Citation:
Zebrafish. 2004;1(2):133-44
Epub:
Not Epub
Abstract:
Although Xenopus studies have shown that Frizzled 7 activates at least two noncanonical signaling pathways, it is less clear...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knowlton MN, Kelly GM. Zebrafish Mir antagonizes Frizzled 7-induced gastrulation defects. Zebrafish. 2004;1(2):133-44.

Zebrafish Polycomb group gene ph2alpha is required for epiboly and tailbud formation acting downstream of FGF signaling

Authors:
Komoike Y, Kawamura A, Shindo N, Sato C, Satoh J, Shiurba R, Higashinakagawa T
Citation:
Biochem Biophys Res Commun. 2005 Mar 25;328(4):858-866
Epub:
Not Epub
Abstract:
We analyzed Polycomb group gene ph2alpha functionally in zebrafish embryos by a gene knock-down procedure using morpholino...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Komoike Y, Kawamura A, Shindo N, Sato C, Satoh J, Shiurba R, Higashinakagawa T. Zebrafish Polycomb group gene ph2alpha is required for epiboly and tailbud formation acting downstream of FGF signaling. Biochem Biophys Res Commun. 2005 Mar 25;328(4):858-866.

A Complex of BBS1 and NPHP7 Is Required for Cilia Motility in Zebrafish

Authors:
Kim YH, Epting D, Slanchev K, Engel C, Walz G, Kramer-Zucker A
Citation:
PLoS ONE. 2013);8(9):e72549. doi:10.1371/journal.pone.0072549
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) and nephronophthisis (NPH) are hereditary autosomal recessive disorders, encoded by two families of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim YH, Epting D, Slanchev K, Engel C, Walz G, Kramer-Zucker A. A Complex of BBS1 and NPHP7 Is Required for Cilia Motility in Zebrafish. PLoS ONE. 2013);8(9):e72549. doi:10.1371/journal.pone.0072549.

A novel Wilms Tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway

Authors:
Kim MS, Yoon SK, Bollig F, Kitagaki J, Hur W, Whye NJ, Wu YP, Rivera MN, Park JY, Kim HS, Malik K, Bell DW, Englert C, Perantoni AO, Lee SB
Citation:
J Biol Chem. 2010 May 7;285(19):14585-93. doi: 10.1074/jbc.M109.094334. Epub 2010 Mar 10.
Epub:
Not Epub
Abstract:
Mammalian kidney development requires the functions of the Wilms tumor gene WT1 and the WNT/beta-catenin signaling pathway....
Organism or Cell Type:
zebrafish
Citation Extract:
Kim MS, Yoon SK, Bollig F, Kitagaki J, Hur W, Whye NJ, Wu YP, Rivera MN, Park JY, Kim HS, Malik K, Bell DW, Englert C, Perantoni AO, Lee SB. A novel Wilms Tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway. J Biol Chem. 2010 May 7;285(19):14585-93. doi: 10.1074/jbc.M109.094334. Epub 2010 Mar 10..

Advanced c-myc antisense (AVI-4126)-eluting phosphorylcholine-coated stent implantation is associated with complete vascular healing and reduced neointimal formation in the porcine coronary restenosis model

Authors:
Kipshidze NN, Iversen P, Kim HS, Yiazdi H, Dangas G, Seaborn R, New G, Tio F, Waksman R, Mehran R, Tsapenko M, Stone GW, Roubin GS, Iyer S, Leon MB, Moses JW
Citation:
Catheter Cardiovasc Interv. 2004 Apr;61(4):518-27
Epub:
Not Epub
Abstract:
An advanced six-ring morpholino backbone c-myc antisense (AVI-4126) was shown to inhibit c-myc expression and intimal...
Delivery Method:
in vivo: coated coronary stent
Organism or Cell Type:
pig
Citation Extract:
Kipshidze NN, Iversen P, Kim HS, Yiazdi H, Dangas G, Seaborn R, New G, Tio F, Waksman R, Mehran R, Tsapenko M, Stone GW, Roubin GS, Iyer S, Leon MB, Moses JW. Advanced c-myc antisense (AVI-4126)-eluting phosphorylcholine-coated stent implantation is associated with complete vascular healing and reduced neointimal formation in the porcine coronary restenosis model. Catheter Cardiovasc Interv. 2004 Apr;61(4):518-27.

Agrin is Required for Posterior Development and Motor Axon Outgrowth and Branching in Embryonic Zebrafish

Authors:
Kim MJ, Liu IH, Song Y, Lee JA, Halfter W, Balice-Gordon RJ, Linney E, Cole GJ
Citation:
Glycobiology. 2007 Feb;17(2):231-47. Epub 2006 Nov 16
Epub:
Not Epub
Abstract:
Although recent studies have extended our understanding of agrin's function during development, its function in the CNS is...
Organism or Cell Type:
zebrafish
Citation Extract:
Kim MJ, Liu IH, Song Y, Lee JA, Halfter W, Balice-Gordon RJ, Linney E, Cole GJ. Agrin is Required for Posterior Development and Motor Axon Outgrowth and Branching in Embryonic Zebrafish. Glycobiology. 2007 Feb;17(2):231-47. Epub 2006 Nov 16.

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