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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

Suppression of macho-1-directed muscle fate by FGF and BMP is required for formation of posterior endoderm in ascidian embryos

Authors:
Kondoh K, Kobayashi K, Nishida H
Citation:
Development. 2003 Jul;130(14):3205-16
Epub:
Not Epub
Abstract:
Specification of germ layers is a crucial event in early embryogenesis. In embryos of the ascidian, Halocynthia roretzi,...
Delivery Method:
Microinjection
Organism or Cell Type:
Halocynthia roretzi (ascidian)
Citation Extract:
Kondoh K, Kobayashi K, Nishida H. Suppression of macho-1-directed muscle fate by FGF and BMP is required for formation of posterior endoderm in ascidian embryos. Development. 2003 Jul;130(14):3205-16.

Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

Authors:
Kloosterman WP, Lagendijk AK, Ketting RF, Moulton JD, Plasterk RH
Citation:
PLoS Biol. 2007 Jul 24;5(8):e203 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Several vertebrate microRNAs (miRNAs) have been implicated in cellular processes such as muscle differentiation, synapse...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kloosterman WP, Lagendijk AK, Ketting RF, Moulton JD, Plasterk RH. Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development. PLoS Biol. 2007 Jul 24;5(8):e203 [Epub ahead of print] .

Targeting mRNA Splicing as a Potential Treatment for Duchenne Muscular Dystrophy

Authors:
Kole R, Leppert BJ
Citation:
Discov Med. 2012;14(74):59-69
Epub:
Not Epub
Abstract:
Several clinical trials have recently demonstrated that oligonucleotide-based drugs induced targeted exon skipping in...
Delivery Method:
iv infusion
Organism or Cell Type:
human
Citation Extract:
Kole R, Leppert BJ. Targeting mRNA Splicing as a Potential Treatment for Duchenne Muscular Dystrophy. Discov Med. 2012;14(74):59-69.

The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds

Authors:
Kobayashi M, Li L, Iwamoto N, Nakajima-Takagi Y, Kaneko H, Nakayama Y, Eguchi M, Wada Y, Kumagai Y, Yamamoto M
Citation:
Mol Cell Biol. 2009 Jan;29(2):493-502. Epub 2008 Nov 10
Epub:
Not Epub
Abstract:
Animals have evolved defense systems for surviving in a chemically diverse environment. Such systems should demonstrate...
Organism or Cell Type:
zebrafish
Citation Extract:
Kobayashi M, Li L, Iwamoto N, Nakajima-Takagi Y, Kaneko H, Nakayama Y, Eguchi M, Wada Y, Kumagai Y, Yamamoto M. The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol Cell Biol. 2009 Jan;29(2):493-502. Epub 2008 Nov 10.

The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain

Authors:
Kizil C, Dudczig S, Kyritsis N, Machate A, Blaesche J, Kroehne V, Brand M
Citation:
Neural Dev. 2012;7:27 doi:10.1186/1749-8104-7-27
Epub:
Not Epub
Abstract:
Background Unlike mammals, zebrafish exhibits extensive neural regeneration after injury in adult stages of its lifetime due to...
Delivery Method:
injection, intracerebroventricular
Organism or Cell Type:
zebrafish
Citation Extract:
Kizil C, Dudczig S, Kyritsis N, Machate A, Blaesche J, Kroehne V, Brand M. The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain. Neural Dev. 2012;7:27 doi:10.1186/1749-8104-7-27.

The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development

Authors:
Kovacevic I, Hu J, Siehoff-Icking A, Opitz N, Griffin A, Perkins AC, Munn AL, Müller-Esterl W, Popp R, Fleming I, Jungblut B, Hoffmeister M, Oess S
Citation:
EMBO J. 2012 Aug 1;31(15):3309-22. doi: 10.1038/emboj.2012.176. Epub 2012 Jun 29
Epub:
Not Epub
Abstract:
F-BAR proteins are multivalent adaptors that link plasma membrane and cytoskeleton and coordinate cellular processes such as...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kovacevic I, Hu J, Siehoff-Icking A, Opitz N, Griffin A, Perkins AC, Munn AL, Müller-Esterl W, Popp R, Fleming I, Jungblut B, Hoffmeister M, Oess S. The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development. EMBO J. 2012 Aug 1;31(15):3309-22. doi: 10.1038/emboj.2012.176. Epub 2012 Jun 29.

The role of Mixer in patterning the early Xenopus embryo

Authors:
Kofron M, Wylie C, Heasman J
Citation:
Development. 2004 May;131(10):2431-41
Epub:
Not Epub
Abstract:
The transcription factor VegT, is required in early Xenopus embryos for the formation of both the mesoderm and endoderm germ...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kofron M, Wylie C, Heasman J. The role of Mixer in patterning the early Xenopus embryo. Development. 2004 May;131(10):2431-41.

The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis

Authors:
Kok FO, Oster E, Mentzer L, Hsieh JC, Henry CA, Sirotkin HI
Citation:
Dev Biol. 2007 Jul 15;307(2):214-26. Epub 2007 May 3
Epub:
Not Epub
Abstract:
Somitogenesis is a highly controlled process that results in segmentation of the paraxial mesoderm. Notch pathway activity in...
Organism or Cell Type:
zebrafish
Citation Extract:
Kok FO, Oster E, Mentzer L, Hsieh JC, Henry CA, Sirotkin HI. The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis. Dev Biol. 2007 Jul 15;307(2):214-26. Epub 2007 May 3.

The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos

Authors:
Kos R, Reedy MV, Johnson RL, Erickson CA
Citation:
Development 2001 128(8):1467-1479
Epub:
Not Epub
Abstract:
The winged-helix or forkhead class of transcription factors has been shown to play important roles in cell specification and...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Kos R, Reedy MV, Johnson RL, Erickson CA. The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development 2001 128(8):1467-1479.

The zebrafish band 4.1 member Mir is involved in cell movements associated with gastrulation

Authors:
Knowlton MN, Chan BM, Kelly GM
Citation:
Dev Biol. 2003 Dec 15;264(2):407-29
Epub:
Not Epub
Abstract:
Cellular processes rely on dynamic events occurring between the cortical cytoskeleton and plasma membrane. Members of the Band...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knowlton MN, Chan BM, Kelly GM. The zebrafish band 4.1 member Mir is involved in cell movements associated with gastrulation. Dev Biol. 2003 Dec 15;264(2):407-29.

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