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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9743 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

Authors:
Alter J, Lou F, Rabinowitz A, Yin H, Rosenfeld J, Wilton SD, Partridge TA, Lu QL
Citation:
Nat Med. 2006 Feb;12(2):175-7. Epub 2006 Jan 29
Abstract:
For the majority of Duchenne muscular dystrophy (DMD) mutations, antisense oligonucleotide (AON)-mediated exon skipping has the...
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Alter J, Lou F, Rabinowitz A, Yin H, Rosenfeld J, Wilton SD, Partridge TA, Lu QL. Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology. Nat Med. 2006 Feb;12(2):175-7. Epub 2006 Jan 29.

T-box gene tbx5 is essential for formation of the pectoral limb bud.

Authors:
Ahn DG, Kourakis MJ, Rohde LA, Silver LM, Ho RK
Citation:
Nature 2002 Jun 13;417(6890):754-8
Abstract:
The T-box genes Tbx4 and Tbx5 have been shown to have key functions in the specification of the identity of the vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahn DG, Kourakis MJ, Rohde LA, Silver LM, Ho RK. T-box gene tbx5 is essential for formation of the pectoral limb bud.. Nature 2002 Jun 13;417(6890):754-8.

The expression profile and function of Satb2 in zebrafish embryonic development

Authors:
Ahn HJ, Park Y, Kim S, Park HC, Seo SK, Yeo SY, Geum D
Citation:
Mol Cells. 2010 Aug 31. [Epub ahead of print]
Abstract:
The present study shows the expression profile and function of the homeobox gene, satb2 during zebrafish embryonic development...
Organism or Cell Type:
zebrafish
Citation Extract:
Ahn HJ, Park Y, Kim S, Park HC, Seo SK, Yeo SY, Geum D. The expression profile and function of Satb2 in zebrafish embryonic development. Mol Cells. 2010 Aug 31. [Epub ahead of print].

The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis

Authors:
Almeida AD, Wise HM, Hindley CJ, Slevin MK, Hartley RS, Philpott A
Citation:
Neural Dev. 2010 Jan 4;5(1):1
Abstract:
ABSTRACT: BACKGROUND: The neural crest is a unique population of cells that arise in the vertebrate ectoderm at the neural...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Almeida AD, Wise HM, Hindley CJ, Slevin MK, Hartley RS, Philpott A. The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis. Neural Dev. 2010 Jan 4;5(1):1.

The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration

Authors:
Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Lori Sussel L
Citation:
Development. 2011;138:3213-3224; doi:10.1242/dev.058693
Abstract:
The homeodomain transcription factor Nkx2.2 is essential for pancreatic development and islet cell type differentiation. We...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Lori Sussel L. The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development. 2011;138:3213-3224; doi:10.1242/dev.058693.

The Liver X-Receptor (Lxr) Governs Lipid Homeostasis in Zebrafish during Development

Authors:
Archer A, Srinivas Kitambi S, Hallgren SL, Pedrelli M, Håkan Olsén K, Mode A, Gustafsson J
Citation:
Open J Endocrine Metabolic Dis. 2012;2(4):74-81. doi: 10.4236/ojemd.2012.24012
Abstract:
The liver X-receptors (LXRs) act as cholesterol sensors and participate in the regulation of lipid and cholesterol metabolism....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Archer A, Srinivas Kitambi S, Hallgren SL, Pedrelli M, Håkan Olsén K, Mode A, Gustafsson J. The Liver X-Receptor (Lxr) Governs Lipid Homeostasis in Zebrafish during Development. Open J Endocrine Metabolic Dis. 2012;2(4):74-81. doi: 10.4236/ojemd.2012.24012.

The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1

Authors:
Agrawal R, Tran U, Wessely O
Citation:
Development. 2009 Dec;136(23):3927-36
Abstract:
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They are...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Agrawal R, Tran U, Wessely O. The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1. Development. 2009 Dec;136(23):3927-36.

The molecular nature of the zebrafish tail organizer

Authors:
Agathon A, Thisse C, Thisse B
Citation:
Nature. 2003 Jul 24;424(6947):448-52.
Abstract:
Based on grafting experiments, Mangold and Spemann showed the dorsal blastopore lip of an amphibian gastrula to be able to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Agathon A, Thisse C, Thisse B. The molecular nature of the zebrafish tail organizer. Nature. 2003 Jul 24;424(6947):448-52..

The polypyrimidine tract binding protein (PTB) prevents the activity of an intronic regulatory element that promotes the usage of a composite 3' terminal exon

Authors:
Anquetil V, Le Sommer C, Méreau A, Hamon S, Lerivray H, Hardy S
Citation:
J Biol Chem. 2009 Sep 17. [Epub ahead of print]
Abstract:
Alternative splicing of 3' terminal exons plays a critical role in gene expression by producing mRNA with distinct 3...
Organism or Cell Type:
Xenopus
Citation Extract:
Anquetil V, Le Sommer C, Méreau A, Hamon S, Lerivray H, Hardy S. The polypyrimidine tract binding protein (PTB) prevents the activity of an intronic regulatory element that promotes the usage of a composite 3' terminal exon. J Biol Chem. 2009 Sep 17. [Epub ahead of print].

The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish

Authors:
Amigo JD, Ackermann GE, Cope JJ, Yu M, Cooney JD, Ma D, Langer NB, Shafizadeh E, Shaw GC, Horsely W, Trede NS, Davidson AJ, Barut BA, Zhou Y, Wojiski SA, Traver D, Moran TB, Kourkoulis G, Hsu K, Kanki JP, Shah DI, Lin HF, Handin RI, Cantor AB, Paw BH
Citation:
Blood. 2009 Nov 19;114(21):4654-63. Epub 2009 Sep 3
Abstract:
The nuclear protein FOG-1 binds transcription factor GATA-1 to facilitate erythroid and megakaryocytic maturation. However,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Amigo JD, Ackermann GE, Cope JJ, Yu M, Cooney JD, Ma D, Langer NB, Shafizadeh E, Shaw GC, Horsely W, Trede NS, Davidson AJ, Barut BA, Zhou Y, Wojiski SA, Traver D, Moran TB, Kourkoulis G, Hsu K, Kanki JP, Shah DI, Lin HF, Handin RI, Cantor AB, Paw BH. The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood. 2009 Nov 19;114(21):4654-63. Epub 2009 Sep 3.

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