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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9876 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Participation of Xenopus ELR-type proteins in vegetal mRNA localization during oogenesis

Authors:
Arthur PK, Claussen M, Koch S, Tarbashevich K, Jahn O, Pieler T
Citation:
J Biol Chem. 2009 Jul 24;284(30):19982-92. Epub 2009 May 20
Abstract:
Directional transport of specific mRNAs is of primary biological relevance. In Xenopus oo-cytes, mRNA localization to the...
Organism or Cell Type:
Xenopus
Citation Extract:
Arthur PK, Claussen M, Koch S, Tarbashevich K, Jahn O, Pieler T. Participation of Xenopus ELR-type proteins in vegetal mRNA localization during oogenesis. J Biol Chem. 2009 Jul 24;284(30):19982-92. Epub 2009 May 20.

Patterning of proneuronal and inter-proneuronal domains by hairy- and enhancer of split-related genes in zebrafish neuroectoderm

Authors:
Bae YK, Shimizu T, Hibi M
Citation:
Development. 2005 Mar;132(6):1375-85. Epub 2005 Feb 16.
Abstract:
In teleosts and amphibians, the proneuronal domains, which give rise to primary-motor, primary-inter and Rohon-Beard (RB)...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bae YK, Shimizu T, Hibi M. Patterning of proneuronal and inter-proneuronal domains by hairy- and enhancer of split-related genes in zebrafish neuroectoderm. Development. 2005 Mar;132(6):1375-85. Epub 2005 Feb 16..

Pax2 and Pea3 synergize to activate a novel regulatory enhancer for spalt4 in the developing ear

Authors:
Barembaum M, Bronner-Fraser M
Citation:
Dev Biol. 2009 Nov 10. [Epub ahead of print]
Abstract:
The transcription factor spalt4 is a key early-response gene in otic placode induction. Here, we characterize the cis-...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Barembaum M, Bronner-Fraser M. Pax2 and Pea3 synergize to activate a novel regulatory enhancer for spalt4 in the developing ear. Dev Biol. 2009 Nov 10. [Epub ahead of print].

Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons

Authors:
Batista MF, Lewis KE
Citation:
Dev Biol. 2008 Nov 1;323(1):88-97. Epub 2008 Aug 18
Abstract:
The spinal cord contains several distinct classes of neurons but it is still unclear how many of the functional characteristics...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Batista MF, Lewis KE. Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons. Dev Biol. 2008 Nov 1;323(1):88-97. Epub 2008 Aug 18.

Perturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system

Authors:
Azuma M, Toyama R, Laver E, Dawid IB
Citation:
J Biol Chem. 2006 May 12;281(19):13309-16. Epub 2006 Mar 10
Abstract:
Zebrafish is a powerful vertebrate model system for using forward genetics to elucidate mechanisms of early development. We...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Azuma M, Toyama R, Laver E, Dawid IB. Perturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system. J Biol Chem. 2006 May 12;281(19):13309-16. Epub 2006 Mar 10.

Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism

Authors:
Arora V, Cate ML, Ghosh C, Iversen PL
Citation:
Drug Metab Dispos. 2002 Jul 1;30(7):757-762
Abstract:
Antisense phosphorodiamidate morpholino oligomers (PMO) inhibit targeted gene expression by preventing ribosomal assembly, thus...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: hepatocytes (human primary cells), Caco-2/h3A4 cells
Citation Extract:
Arora V, Cate ML, Ghosh C, Iversen PL. Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism. Drug Metab Dispos. 2002 Jul 1;30(7):757-762.

Proliferation of embryonic cardiomyocytes in zebrafish requires the sodium channel scn5Lab

Authors:
Bennett J, Stroud D, Becker J, Roden D
Citation:
Genesis. 2013 May 3. doi: 10.1002/dvg.22400. [Epub ahead of print]
Abstract:
In mice, homozygous deletion of the cardiac sodium channel Scn5a results in defects in cardiac morphology and embryonic death...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bennett J, Stroud D, Becker J, Roden D. Proliferation of embryonic cardiomyocytes in zebrafish requires the sodium channel scn5Lab. Genesis. 2013 May 3. doi: 10.1002/dvg.22400. [Epub ahead of print].

Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours

Authors:
Azoitei N, Pusapati GV, Kleger A, Möller P, Küfer R, Genze F, Wagner M, van Lint J, Carmeliet P, Adler G, Seufferlein T
Citation:
Gut. 2010 Aug 23. [Epub ahead of print]
Abstract:
Background Tumour angiogenesis is crucially dependent on the communication between the tumour and the associated endothelium....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice, NMRI nu/nu
Citation Extract:
Azoitei N, Pusapati GV, Kleger A, Möller P, Küfer R, Genze F, Wagner M, van Lint J, Carmeliet P, Adler G, Seufferlein T. Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours. Gut. 2010 Aug 23. [Epub ahead of print].

Protein O-mannosylation is necessary for normal embryonic development in zebrafish

Authors:
Avsar-Ban E, Ishikawa H, Manya H, Watanabe M, Akiyama S, Miyake H, Endo T, Tamaru Y
Citation:
Glycobiology. 2010 May 10. [Epub ahead of print]
Abstract:
Two distinct cDNAs corresponding to two zebrafish protein O-mannosyltransferase genes, zPOMT1 and zPOMT2, were cloned from...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Avsar-Ban E, Ishikawa H, Manya H, Watanabe M, Akiyama S, Miyake H, Endo T, Tamaru Y. Protein O-mannosylation is necessary for normal embryonic development in zebrafish. Glycobiology. 2010 May 10. [Epub ahead of print].

Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5

Authors:
Berfield AK, Hansen K, Abrass CK
Citation:
Am J Physiol Cell Physiol. 2006 Oct;291(4):C589-99. Epub 2006 May 3.
Abstract:
Temporal and spatial differences in extracellular matrix play critical roles in cell proliferation, differentiation and...
Delivery Method:
Special Delivery
Organism or Cell Type:
Cell culture: Rat glomerular mesangial cells
Citation Extract:
Berfield AK, Hansen K, Abrass CK. Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5. Am J Physiol Cell Physiol. 2006 Oct;291(4):C589-99. Epub 2006 May 3..

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