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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9716 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Splice Redirection as a Convenient Assay to Monitor CPP-ON Efficiency and Mechanism

Authors:
Abes R, Arzumanov AA, Saleh AF, Said Hassane F, Gait MJ, Lebleu B
Citation:
Methods Mol Biol. 2011;683:307-20
Abstract:
Several strategies based on synthetic oligonucleotides (ON) have been proposed to control gene expression. As for most...
Delivery Method:
peptide-coupled
Citation Extract:
Abes R, Arzumanov AA, Saleh AF, Said Hassane F, Gait MJ, Lebleu B. Splice Redirection as a Convenient Assay to Monitor CPP-ON Efficiency and Mechanism. Methods Mol Biol. 2011;683:307-20.

Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia

Authors:
Arniges M, Vazquez E, Fernandez-Fernandez JM, Valverde MA
Citation:
J Biol Chem. 2004 Dec 24;279(52):54062-8. Epub 2004 Oct 15
Abstract:
The vertebrate transient receptor potential cationic channel TRPV4 has been proposed as an osmo- and mechanosensor channel....
Delivery Method:
transfection
Organism or Cell Type:
cell culture: CFT1 cells
Citation Extract:
Arniges M, Vazquez E, Fernandez-Fernandez JM, Valverde MA. Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia. J Biol Chem. 2004 Dec 24;279(52):54062-8. Epub 2004 Oct 15.

Synthesis and Properties of Nucleic Acid Methylene Carboxamide Mimics Derived from Morpholine Nucleosides

Authors:
Abramova TV, Kassakin MF, Tarasenko YV, Lomzov AA, Koval VV, Pyshnyi DV, Silnikov VN
Citation:
Russian Journal of Bioorganic Chemistry, 2012, Vol. 38, No. 4, pp. 400–411.
Abstract:
Uracyl and adenine containing oligomers derived from carboxymethyl derivatives of morpholine nucleoside analogues (MorGly) were...
Citation Extract:
Abramova TV, Kassakin MF, Tarasenko YV, Lomzov AA, Koval VV, Pyshnyi DV, Silnikov VN. Synthesis and Properties of Nucleic Acid Methylene Carboxamide Mimics Derived from Morpholine Nucleosides. Russian Journal of Bioorganic Chemistry, 2012, Vol. 38, No. 4, pp. 400–411..

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

Authors:
Alter J, Lou F, Rabinowitz A, Yin H, Rosenfeld J, Wilton SD, Partridge TA, Lu QL
Citation:
Nat Med. 2006 Feb;12(2):175-7. Epub 2006 Jan 29
Abstract:
For the majority of Duchenne muscular dystrophy (DMD) mutations, antisense oligonucleotide (AON)-mediated exon skipping has the...
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Alter J, Lou F, Rabinowitz A, Yin H, Rosenfeld J, Wilton SD, Partridge TA, Lu QL. Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology. Nat Med. 2006 Feb;12(2):175-7. Epub 2006 Jan 29.

T-box gene tbx5 is essential for formation of the pectoral limb bud.

Authors:
Ahn DG, Kourakis MJ, Rohde LA, Silver LM, Ho RK
Citation:
Nature 2002 Jun 13;417(6890):754-8
Abstract:
The T-box genes Tbx4 and Tbx5 have been shown to have key functions in the specification of the identity of the vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahn DG, Kourakis MJ, Rohde LA, Silver LM, Ho RK. T-box gene tbx5 is essential for formation of the pectoral limb bud.. Nature 2002 Jun 13;417(6890):754-8.

The expression profile and function of Satb2 in zebrafish embryonic development

Authors:
Ahn HJ, Park Y, Kim S, Park HC, Seo SK, Yeo SY, Geum D
Citation:
Mol Cells. 2010 Aug 31. [Epub ahead of print]
Abstract:
The present study shows the expression profile and function of the homeobox gene, satb2 during zebrafish embryonic development...
Organism or Cell Type:
zebrafish
Citation Extract:
Ahn HJ, Park Y, Kim S, Park HC, Seo SK, Yeo SY, Geum D. The expression profile and function of Satb2 in zebrafish embryonic development. Mol Cells. 2010 Aug 31. [Epub ahead of print].

The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis

Authors:
Almeida AD, Wise HM, Hindley CJ, Slevin MK, Hartley RS, Philpott A
Citation:
Neural Dev. 2010 Jan 4;5(1):1
Abstract:
ABSTRACT: BACKGROUND: The neural crest is a unique population of cells that arise in the vertebrate ectoderm at the neural...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Almeida AD, Wise HM, Hindley CJ, Slevin MK, Hartley RS, Philpott A. The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis. Neural Dev. 2010 Jan 4;5(1):1.

The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration

Authors:
Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Lori Sussel L
Citation:
Development. 2011;138:3213-3224; doi:10.1242/dev.058693
Abstract:
The homeodomain transcription factor Nkx2.2 is essential for pancreatic development and islet cell type differentiation. We...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Lori Sussel L. The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development. 2011;138:3213-3224; doi:10.1242/dev.058693.

The Liver X-Receptor (Lxr) Governs Lipid Homeostasis in Zebrafish during Development

Authors:
Archer A, Srinivas Kitambi S, Hallgren SL, Pedrelli M, Håkan Olsén K, Mode A, Gustafsson J
Citation:
Open J Endocrine Metabolic Dis. 2012;2(4):74-81. doi: 10.4236/ojemd.2012.24012
Abstract:
The liver X-receptors (LXRs) act as cholesterol sensors and participate in the regulation of lipid and cholesterol metabolism....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Archer A, Srinivas Kitambi S, Hallgren SL, Pedrelli M, Håkan Olsén K, Mode A, Gustafsson J. The Liver X-Receptor (Lxr) Governs Lipid Homeostasis in Zebrafish during Development. Open J Endocrine Metabolic Dis. 2012;2(4):74-81. doi: 10.4236/ojemd.2012.24012.

The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1

Authors:
Agrawal R, Tran U, Wessely O
Citation:
Development. 2009 Dec;136(23):3927-36
Abstract:
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They are...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Agrawal R, Tran U, Wessely O. The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1. Development. 2009 Dec;136(23):3927-36.

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