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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10344 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway

Authors:
Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W
Citation:
J Biol Chem. 2009 Dec 11;284(50):35040-8. Epub 2009 Oct 2
Abstract:
Wnt ligands conduct their functions in canonical Wnt signaling by binding to two receptors, the single transmembrane low...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen M, Philipp M, Wang J, Premont RT, Garrison TR, Caron MG, Lefkowitz RJ, Chen W. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway. J Biol Chem. 2009 Dec 11;284(50):35040-8. Epub 2009 Oct 2.

Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System

Authors:
Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan LY, Tristani-Firouzi M, Stainier DY
Citation:
PLoS Biol. 2008 May 13;6(5):e109. [Epub ahead of print]
Abstract:
Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan LY, Tristani-Firouzi M, Stainier DY. Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System. PLoS Biol. 2008 May 13;6(5):e109. [Epub ahead of print].

Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition

Authors:
Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M
Citation:
Genes Dev. 2011 Apr 1;25(7):755-66
Abstract:
Oocyte maturation, fertilization, and early embryonic development occur in the absence of gene transcription. Therefore, it is...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M. Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 1;25(7):755-66.

Genomic selection identifies vertebrate transcription factor Fezf2 binding sites and target genes

Authors:
Chen L, Zheng J, Yang N, Li H, Guo S
Citation:
J Biol Chem. 2011 May 27;286(21):18641-9. Epub 2011 Apr 6
Abstract:
Identification of transcription factor targets is critical to understanding gene regulatory networks. Here, we uncover...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen L, Zheng J, Yang N, Li H, Guo S. Genomic selection identifies vertebrate transcription factor Fezf2 binding sites and target genes. J Biol Chem. 2011 May 27;286(21):18641-9. Epub 2011 Apr 6.

Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays

Authors:
Cheung HC, Baggerly KA, Tsavachidis S, Bachinski LL, Neubauer VL, Nixon TJ, Aldape KD, Cote GJ, Krahe R
Citation:
BMC Genomics. 2008 May 12;9:216
Abstract:
BACKGROUND: Tumor-predominant splice isoforms were identified during comparative in silico sequence analysis of EST clones,...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: human glioma lines, tumors and non-tumor barin
Citation Extract:
Cheung HC, Baggerly KA, Tsavachidis S, Bachinski LL, Neubauer VL, Nixon TJ, Aldape KD, Cote GJ, Krahe R. Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays. BMC Genomics. 2008 May 12;9:216.

Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish

Authors:
Chen Q, Jiang L, Li C, Hu D, Bu J, Cai D, Du J
Citation:
PLoS Biol. 2012;10(8): e1001374. doi:10.1371/journal.pbio.1001374
Abstract:
Although the brain comprises only 2% of body weight, it receives 15% of cardiac output and consumes 20% of total body oxygen...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Q, Jiang L, Li C, Hu D, Bu J, Cai D, Du J. Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish. PLoS Biol. 2012;10(8): e1001374. doi:10.1371/journal.pbio.1001374.

Histone Deacetylase (HDAC) Activity Is Critical for Embryonic Kidney Gene Expression, Growth, and Differentiation

Authors:
Chen S, Bellew C, Yao X, Stefkova J, Dipp S, Saifudeen Z, Bachvarov D, El-Dahr SS
Citation:
J Biol Chem. 2011 Sep 16;286(37):32775-89. Epub 2011 Jul 21
Abstract:
Histone deacetylases (HDACs) regulate fundamental biological processes such as cellular proliferation, differentiation, and...
Delivery Method:
Endo-Porter
Organism or Cell Type:
organ culture: mouse kidney
Citation Extract:
Chen S, Bellew C, Yao X, Stefkova J, Dipp S, Saifudeen Z, Bachvarov D, El-Dahr SS. Histone Deacetylase (HDAC) Activity Is Critical for Embryonic Kidney Gene Expression, Growth, and Differentiation. J Biol Chem. 2011 Sep 16;286(37):32775-89. Epub 2011 Jul 21.

HNF factors form a network to regulate liver-enriched genes in zebrafish

Authors:
Cheng W, Guo L, Zhang Z, Soo HM, Wen C, Wu W, Peng J
Citation:
Dev Biol. 2006 Jun 15;294(2):482-96. Epub 2006 Apr 24.
Abstract:
Defects in some of liver-enriched genes in mammals will cause liver- and/or blood-related diseases. However, due to the fact...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng W, Guo L, Zhang Z, Soo HM, Wen C, Wu W, Peng J. HNF factors form a network to regulate liver-enriched genes in zebrafish. Dev Biol. 2006 Jun 15;294(2):482-96. Epub 2006 Apr 24..

hnf1b genes in zebrafish hindbrain development

Authors:
Choe SK, Hirsch N, Zhang X, Sagerström CG
Citation:
Zebrafish. 2008 Sep;5(3):179-87
Abstract:
The Hnf1b transcription factor acts during formation of rhombomeres (r) 5 and 6 in the hindbrain. To determine if hnf1b is...
Organism or Cell Type:
zebrafish
Citation Extract:
Choe SK, Hirsch N, Zhang X, Sagerström CG. hnf1b genes in zebrafish hindbrain development. Zebrafish. 2008 Sep;5(3):179-87.

Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11)

Authors:
Chiang AP, Beck JS, Yen HJ, Tayeh MK, Scheetz TE, Swiderski RE, Nishimura DY, Braun TA, Kim KY, Huang J, Elbedour K, Carmi R, Slusarski DC, Casavant TL, Stone EM, Sheffield VC
Citation:
Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6287-92. Epub 2006 Apr 10
Abstract:
The identification of mutations in genes that cause human diseases has largely been accomplished through the use of positional...
Organism or Cell Type:
zebrafish
Citation Extract:
Chiang AP, Beck JS, Yen HJ, Tayeh MK, Scheetz TE, Swiderski RE, Nishimura DY, Braun TA, Kim KY, Huang J, Elbedour K, Carmi R, Slusarski DC, Casavant TL, Stone EM, Sheffield VC. Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6287-92. Epub 2006 Apr 10.

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