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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9876 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Redirection of drug metabolism using antisense technology

Authors:
Arora V, Iversen PL
Citation:
Curr Opin Mol Ther. 2001 Jun;3(3):249-57. Review.
Abstract:
The cytochrome P450 (CYP) family is the most catalytically versatile component of the phase I oxidation metabolic pathway and...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Arora V, Iversen PL. Redirection of drug metabolism using antisense technology. Curr Opin Mol Ther. 2001 Jun;3(3):249-57. Review..

Responses of Human Cells to PAH-Induced DNA Damage

Authors:
Baird WM, Hooven LA, Mahadevan B, Luch A, Seidel A, Iversen PL
Citation:
Polycyclic Aromatic Compounds . 2002; 22(3-4): 771 - 780
Abstract:
Benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) induce cytochrome P450 (CYP) CYP1A1 and CYP1B1, which metabolize these...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: human MCF-7 cells
Citation Extract:
Baird WM, Hooven LA, Mahadevan B, Luch A, Seidel A, Iversen PL. Responses of Human Cells to PAH-Induced DNA Damage. Polycyclic Aromatic Compounds . 2002; 22(3-4): 771 - 780.

roundabout4 is essential for angiogenesis in vivo

Authors:
Bedell VM, Yeo SY, Park KW, Chung J, Seth P, Shivalingappa V, Zhao J, Obara T, Sukhatme VP, Drummond IA, Li DY, Ramchandran R
Citation:
Proc Natl Acad Sci U S A. 2005 May 3;102(18):6373-8. Epub 2005 Apr 22
Abstract:
Stereotypical patterns of vascular and neuronal networks suggest that specific genetic programs tightly control path...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bedell VM, Yeo SY, Park KW, Chung J, Seth P, Shivalingappa V, Zhao J, Obara T, Sukhatme VP, Drummond IA, Li DY, Ramchandran R. roundabout4 is essential for angiogenesis in vivo. Proc Natl Acad Sci U S A. 2005 May 3;102(18):6373-8. Epub 2005 Apr 22.

Scaling of the BMP activation gradient in Xenopus embryos

Authors:
Ben-Zvi D, Shilo BZ, Fainsod A, Barkai N
Citation:
Nature. 2008 Jun 26;453(7199):1205-11
Abstract:
In groundbreaking experiments, Hans Spemann demonstrated that the dorsal part of the amphibian embryo can generate a well-...
Organism or Cell Type:
Xenopus
Citation Extract:
Ben-Zvi D, Shilo BZ, Fainsod A, Barkai N. Scaling of the BMP activation gradient in Xenopus embryos. Nature. 2008 Jun 26;453(7199):1205-11.

Sdc2 and Tbx16 regulate Fgf2-dependent epithelial cell morphogenesis in the ciliated organ of asymmetry

Authors:
Arrington CB, Peterson AG, Yost HJ
Citation:
Development. 2013 Oct;140(19):4102-9. doi: 10.1242/dev.096933
Abstract:
Heparan sulfate proteoglycans (HSPGs) control many cellular processes and have been implicated in the regulation of left-right...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Arrington CB, Peterson AG, Yost HJ. Sdc2 and Tbx16 regulate Fgf2-dependent epithelial cell morphogenesis in the ciliated organ of asymmetry. Development. 2013 Oct;140(19):4102-9. doi: 10.1242/dev.096933.

Semaphorin 3d promotes cell proliferation and neural crest cell development downstream of TCF in the zebrafish hindbrain

Authors:
Berndt JD, Halloran MC
Citation:
Development. 2006 Oct;133(20):3983-92. Epub 2006 Sep 13.
Abstract:
Neural crest cells (NCCs) are pluripotent migratory cells that are crucial to the development of the peripheral nervous system...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berndt JD, Halloran MC. Semaphorin 3d promotes cell proliferation and neural crest cell development downstream of TCF in the zebrafish hindbrain. Development. 2006 Oct;133(20):3983-92. Epub 2006 Sep 13..

Short-chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development

Authors:
Belyaeva OV, Lee SA, Adams MK, Chang C, Kedishvili NY
Citation:
J. Biol. Chem. 2012;[Epub ahead of print] doi:10.1074/jbc.M111.336727
Abstract:
The enzymes responsible for the rate-limiting step in retinoic acid biosynthesis, the oxidation of retinol to retinaldehyde,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Belyaeva OV, Lee SA, Adams MK, Chang C, Kedishvili NY. Short-chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development. J. Biol. Chem. 2012;[Epub ahead of print] doi:10.1074/jbc.M111.336727.

Siamois and Twin are redundant and essential in formation of the Spemann organizer

Authors:
Bae S, Reid CD, Kessler DS
Citation:
Dev Biol. 2011 Apr 15;352(2):367-81. Epub 2011 Feb 3
Abstract:
The Spemann organizer is an essential signaling center in Xenopus germ layer patterning and axis formation. Organizer formation...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Bae S, Reid CD, Kessler DS. Siamois and Twin are redundant and essential in formation of the Spemann organizer. Dev Biol. 2011 Apr 15;352(2):367-81. Epub 2011 Feb 3.

SMIF, a Smad4-interacting protein that functions as a co-activator in TGF [beta] signalling

Authors:
Bai RY, Koester C, Ouyang T, Hahn SA, Hammerschmidt M, Peschel C, Duyster J
Citation:
Nat Cell Biol 2002 Mar;4 (3):181-90
Abstract:
Proteins of the transforming growth factor beta(TGFbeta) superfamily regulate diverse cellular responses, including cell growth...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bai RY, Koester C, Ouyang T, Hahn SA, Hammerschmidt M, Peschel C, Duyster J. SMIF, a Smad4-interacting protein that functions as a co-activator in TGF [beta] signalling. Nat Cell Biol 2002 Mar;4 (3):181-90.

Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord

Authors:
Belgacem YH, Borodinsky LN
Citation:
Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4482-7. Epub 2011 Feb 28.
Abstract:
Evolutionarily conserved hedgehog proteins orchestrate the patterning of embryonic tissues, and dysfunctions in their signaling...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Belgacem YH, Borodinsky LN. Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4482-7. Epub 2011 Feb 28..

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