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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Calcineurin Interacts with PERK and Dephosphorylates Calnexin to Relieve ER Stress in Mammals and Frogs

Authors:
Bollo M, Paredes RM, Holstein D, Zheleznova N, Camacho P, Lechleiter JD
Citation:
PLoS One. 2010 Aug 5;5(8). pii: e11925
Epub:
Not Epub
Abstract:
The accumulation of misfolded proteins within the endoplasmic reticulum (ER) triggers a cellular process known as the Unfolded...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bollo M, Paredes RM, Holstein D, Zheleznova N, Camacho P, Lechleiter JD. Calcineurin Interacts with PERK and Dephosphorylates Calnexin to Relieve ER Stress in Mammals and Frogs. PLoS One. 2010 Aug 5;5(8). pii: e11925.

Caveolin-1 upregulation in diabetic fibroblasts and wounded tissues: implication for understanding the underlying mechanisms of non-healing diabetic ulcers

Authors:
Bitar MS, Abdel-Halim SM, Al-Mulla F
Citation:
Am J Physiol Endocrinol Metab. 2013 Aug 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
A heightened state of oxidative stress and senescence of fibroblasts constitute potential therapeutic targets in non-healing...
Delivery Method:
Vivo-Morpholino
Citation Extract:
Bitar MS, Abdel-Halim SM, Al-Mulla F. Caveolin-1 upregulation in diabetic fibroblasts and wounded tissues: implication for understanding the underlying mechanisms of non-healing diabetic ulcers. Am J Physiol Endocrinol Metab. 2013 Aug 13. [Epub ahead of print].

Cell Penetrating Peptide Delivery of Splice Directing Oligonucleotides as a Treatment for Duchenne Muscular Dystrophy

Authors:
Betts CA, Wood MJ
Citation:
Curr Pharm Des. 2013;19(16):2948-62. doi: 10.2174/1381612811319160009. PMID: 23140454
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy is a severe, X-linked muscle wasting disorder caused by the absence of an integral structural...
Link:
https://www.eurekaselect.com/article/50268
Delivery Method:
peptide-coupled
Citation Extract:
Betts CA, Wood MJ. Cell Penetrating Peptide Delivery of Splice Directing Oligonucleotides as a Treatment for Duchenne Muscular Dystrophy. Curr Pharm Des. 2013;19(16):2948-62. doi: 10.2174/1381612811319160009. PMID: 23140454.

Chromatin immunoprecipitation in early Xenopus laevis embryos

Authors:
Blythe SA, Reid CD, Kessler DS, Klein PS
Citation:
Dev Dyn. 2009 Jun;238(6):1422-32
Epub:
Not Epub
Abstract:
Chromatin immunoprecipitation (ChIP) is a powerful method for analyzing the interaction of regulatory proteins with genomic...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Blythe SA, Reid CD, Kessler DS, Klein PS. Chromatin immunoprecipitation in early Xenopus laevis embryos. Dev Dyn. 2009 Jun;238(6):1422-32.

Connexin26-mediated transfer of laterality cues in Xenopus

Authors:
Beyer T, Thumberger T, Schweickert A, Blum M
Citation:
Biology Open. 2012; [Epub ahead of print] doi:10.1242/bio.2012760
Epub:
Not Epub
Abstract:
A cilia-driven leftward flow of extracellular fluid breaks bilateral symmetry in the dorsal midline of the neurula stage...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Beyer T, Thumberger T, Schweickert A, Blum M. Connexin26-mediated transfer of laterality cues in Xenopus. Biology Open. 2012; [Epub ahead of print] doi:10.1242/bio.2012760 .

Conserved and acquired features of neurogenin1 regulation

Authors:
Blader P, Lam CS, Rastegar S, Scardigli R, Nicod JC, Simplicio N, Plessy C, Fischer N, Schuurmans C, Guillemot F, Strähle U
Citation:
Development. 2004 Nov;131(22):5627-37. Epub 2004 Oct 20
Epub:
Not Epub
Abstract:
The telencephalon shows vast morphological variations among different vertebrate groups. The transcription factor neurogenin1 (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blader P, Lam CS, Rastegar S, Scardigli R, Nicod JC, Simplicio N, Plessy C, Fischer N, Schuurmans C, Guillemot F, Strähle U. Conserved and acquired features of neurogenin1 regulation. Development. 2004 Nov;131(22):5627-37. Epub 2004 Oct 20.

Control of chemokine-guided cell migration by ligand sequestration

Authors:
Boldajipour B, Mahabaleshwar H, Kardash E, Reichman-Fried M, Blaser H, Minina S, Wilson D, Xu Q, Raz E
Citation:
Cell. 2008 Feb 8;132(3):463-73
Epub:
Not Epub
Abstract:
Primordial germ cell (PGC) migration in zebrafish is directed by the chemokine SDF-1a that activates its receptor CXCR4b....
Organism or Cell Type:
zebrafish
Citation Extract:
Boldajipour B, Mahabaleshwar H, Kardash E, Reichman-Fried M, Blaser H, Minina S, Wilson D, Xu Q, Raz E. Control of chemokine-guided cell migration by ligand sequestration. Cell. 2008 Feb 8;132(3):463-73.

cpsf1 is required for definitive hematopoietic stem cell survival in zebrafish

Authors:
Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT
Citation:
Blood. 2011 Apr 14;117(15):3996-4007. doi: 10.1182/blood-2010-08-304030. Epub 2011 Feb 17
Epub:
Not Epub
Abstract:
A comprehensive understanding of genes and pathways regulating hematopoiesis is needed to identify genes causally related to...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087528/
Organism or Cell Type:
zebrafish
Citation Extract:
Bolli N, Payne EM, Rhodes J, Gjini E, Johnston AB, Guo F, Lee JS, Stewart RA, Kanki JP, Chen AT, Zhou Y, Zon LI, Look AT. cpsf1 is required for definitive hematopoietic stem cell survival in zebrafish. Blood. 2011 Apr 14;117(15):3996-4007. doi: 10.1182/blood-2010-08-304030. Epub 2011 Feb 17.

Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis

Authors:
Blanca L, Ciciotteb SL, Gwynnb B, Hildick-Smithc GJ, Piercec EL, Soltisc KA, Cooneyc JD, Pawc BH, Petersa LL
Citation:
PNAS 2012 July 6 [Epub ahead of print] doi: 10.1073/pnas.1204948109
Epub:
Not Epub
Abstract:
Phenotype-driven approaches to gene discovery using inbred mice have been instrumental in identifying genetic determinants of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blanca L, Ciciotteb SL, Gwynnb B, Hildick-Smithc GJ, Piercec EL, Soltisc KA, Cooneyc JD, Pawc BH, Petersa LL. Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis. PNAS 2012 July 6 [Epub ahead of print] doi: 10.1073/pnas.1204948109.

CVAK104 is a Novel Regulator of Clathrin-mediated SNARE Sorting

Authors:
Borner GH, Rana AA, Forster R, Harbour M, Smith JC, Robinson MS
Citation:
Traffic. 2007 Jul;8(7):893-903
Epub:
Not Epub
Abstract:
Clathrin-coated vesicles (CCVs) mediate transport between the plasma membrane, endosomes and the trans Golgi network. Using...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Borner GH, Rana AA, Forster R, Harbour M, Smith JC, Robinson MS. CVAK104 is a Novel Regulator of Clathrin-mediated SNARE Sorting. Traffic. 2007 Jul;8(7):893-903.

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