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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus

Authors:
Beunders G, Voorhoeve E, Golzio C, Pardo LM, Rosenfeld JA, Talkowski ME, Simonic I, Lionel AC, Vergult S, Pyatt RE, van de Kamp J, Nieuwint A, Weiss MM, Rizzu P, Verwer LE, van Spaendonk RM, Shen Y, Wu BL, Yu T, Yu Y, Chiang C, Gusella JF, Lindgren AM, Morton CC, van Binsbergen E, Bulk S, van Rossem E, Vanakker O, Armstrong R, Park SM, Greenhalgh L, Maye U, Neill NJ, Abbott KM, Sell S, Ladda R, Farber DM, Bader PI, Cushing T, Drautz JM, Konczal L, Nash P, de Los Reyes E, Carter MT, Hopkins E, Marshall CR, Osborne LR, Gripp KW, Thrush DL, Hashimoto S, Gastier-Foster JM, Astbury C, Ylstra B, Meijers-Heijboer H, Posthuma D, Menten B, Mortier G, Scherer SW, Eichler EE, Girirajan S, Katsanis N, Groffen AJ, Sistermans EA.
Citation:
Am J Hum Genet. 2013 Feb 7;92(2):210-20. doi: 10.1016/j.ajhg.2012.12.011. Epub 2013 Jan 17.
Epub:
Not Epub
Abstract:
Genomic rearrangements involving AUTS2 (7q11.22) are associated with autism and intellectual disability (ID), although evidence...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Beunders G, Voorhoeve E, Golzio C, Pardo LM, Rosenfeld JA, Talkowski ME, Simonic I, Lionel AC, Vergult S, Pyatt RE, van de Kamp J, Nieuwint A, Weiss MM, Rizzu P, Verwer LE, van Spaendonk RM, Shen Y, Wu BL, Yu T, Yu Y, Chiang C, Gusella JF, Lindgren AM, Morton CC, van Binsbergen E, Bulk S, van Rossem E, Vanakker O, Armstrong R, Park SM, Greenhalgh L, Maye U, Neill NJ, Abbott KM, Sell S, Ladda R, Farber DM, Bader PI, Cushing T, Drautz JM, Konczal L, Nash P, de Los Reyes E, Carter MT, Hopkins E, Marshall CR, Osborne LR, Gripp KW, Thrush DL, Hashimoto S, Gastier-Foster JM, Astbury C, Ylstra B, Meijers-Heijboer H, Posthuma D, Menten B, Mortier G, Scherer SW, Eichler EE, Girirajan S, Katsanis N, Groffen AJ, Sistermans EA. . Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus. Am J Hum Genet. 2013 Feb 7;92(2):210-20. doi: 10.1016/j.ajhg.2012.12.011. Epub 2013 Jan 17..

Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish

Authors:
Bolli N, Payne EM, Grabher C, Lee JS, Johnston AB, Falini B, Kanki JP, Look AT
Citation:
Blood. 2010 Apr 22;115(16):3329-40. Epub 2010 Mar 2
Epub:
Not Epub
Abstract:
Mutations in the human nucleophosmin (NPM1) gene are the most frequent genetic alteration in adult acute myeloid leukemias (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bolli N, Payne EM, Grabher C, Lee JS, Johnston AB, Falini B, Kanki JP, Look AT. Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish. Blood. 2010 Apr 22;115(16):3329-40. Epub 2010 Mar 2.

Expression of the Ku70 subunit (XRCC6) and protection from low dose ionizing radiation during zebrafish embryogenesis

Authors:
Bladen CL, Navarre S, Dynan WS, Kozlowski DJ
Citation:
Neurosci Lett. 2007 Jul 11;422(2):97-102. Epub 2007 Jun 2.
Epub:
Not Epub
Abstract:
The Ku70 protein, a product of the XRCC6 gene, is a component of the nonhomologous end-joining (NHEJ) pathway of DNA repair,...
Organism or Cell Type:
zebrafish
Citation Extract:
Bladen CL, Navarre S, Dynan WS, Kozlowski DJ. Expression of the Ku70 subunit (XRCC6) and protection from low dose ionizing radiation during zebrafish embryogenesis. Neurosci Lett. 2007 Jul 11;422(2):97-102. Epub 2007 Jun 2..

Factor Associated with Neutral Sphingomyelinase Activity Mediates Navigational Capacity of Leukocytes Responding to Wounds and Infection: Live Imaging Studies in Zebrafish Larvae

Authors:
Boecke A, Sieger D, Neacsu CD, Kashkar H, Krönke M
Citation:
J Immunol. 2012 Jul 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Factor associated with neutral sphingomyelinase activity (FAN) is an adaptor protein that specifically binds to the p55...
Organism or Cell Type:
zebrafish
Citation Extract:
Boecke A, Sieger D, Neacsu CD, Kashkar H, Krönke M. Factor Associated with Neutral Sphingomyelinase Activity Mediates Navigational Capacity of Leukocytes Responding to Wounds and Infection: Live Imaging Studies in Zebrafish Larvae. J Immunol. 2012 Jul 16. [Epub ahead of print].

Fibroblast Growth Factor (FGF) Signaling during Gastrulation Negatively Modulates the Abundance of MicroRNAs That Regulate Proteins Required for Cell Migration and Embryo Patterning

Authors:
Bobbs AS, Saarela AV, Yatskievych TA, Antin PB
Citation:
J Biol Chem. 2012;287:38505-38514. doi:10.1074/jbc.M112.400598
Epub:
Not Epub
Abstract:
FGF signaling plays a pivotal role in regulating cell movements and lineage induction during gastrulation. Here we identify 44...
Organism or Cell Type:
chick embryo
Citation Extract:
Bobbs AS, Saarela AV, Yatskievych TA, Antin PB. Fibroblast Growth Factor (FGF) Signaling during Gastrulation Negatively Modulates the Abundance of MicroRNAs That Regulate Proteins Required for Cell Migration and Embryo Patterning. J Biol Chem. 2012;287:38505-38514. doi:10.1074/jbc.M112.400598.

Functional Analysis of Wnt Signaling in the Early Sea Urchin Embryo Using mRNA Microinjection

Authors:
Bince JM, Wikramanayake AH
Citation:
Methods Mol Biol. 2009;469:213-222
Epub:
Not Epub
Abstract:
The Wnt pathway is a highly conserved signal transduction pathway that plays many critical roles in early animal development....
Delivery Method:
Microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Bince JM, Wikramanayake AH. Functional Analysis of Wnt Signaling in the Early Sea Urchin Embryo Using mRNA Microinjection. Methods Mol Biol. 2009;469:213-222.

Gene Knock-down in Rainbow Trout Embryos Using Antisense Morpholino Phosphorodiamidate Oligonucleotides

Authors:
Boonanuntanasarn S, Yoshizaki G, Takeuchi Y, Morita T, and Takeuchi T
Citation:
Marine Biotechnology 2002. 4:256-266
Epub:
Not Epub
Abstract:
Gene knock-down technology using antisense molecules has many applications for studying gene function, disrupting undesirable...
Delivery Method:
Microinjection
Organism or Cell Type:
rainbow trout
Citation Extract:
Boonanuntanasarn S, Yoshizaki G, Takeuchi Y, Morita T, and Takeuchi T. Gene Knock-down in Rainbow Trout Embryos Using Antisense Morpholino Phosphorodiamidate Oligonucleotides. Marine Biotechnology 2002. 4:256-266.

Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest

Authors:
Betancur P, Bronner-Fraser M, Sauka-Spengler T
Citation:
Proc Natl Acad Sci U S A. 2010 Feb 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The neural crest is a multipotent, stem cell-like population that migrates extensively in the embryo and forms a wide array of...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Betancur P, Bronner-Fraser M, Sauka-Spengler T. Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest. Proc Natl Acad Sci U S A. 2010 Feb 5. [Epub ahead of print].

Heparan sulfate 6-O-sulfotransferase is essential for muscle development in Zebrafish

Authors:
Bink RJ, Habuchi H, Lele Z, Dolk E, Joore J, Rauch GJ, Geisler R, Wilson SW, Den Hertog J, Kimata K, Zivkovic D
Citation:
J Biol Chem. 2003 Aug 15;278(33):31118-27. Epub 2003 Jun 01.
Epub:
Not Epub
Abstract:
Heparan sulfate proteoglycans function in development and disease. They consist of a core protein with attached heparan sulfate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bink RJ, Habuchi H, Lele Z, Dolk E, Joore J, Rauch GJ, Geisler R, Wilson SW, Den Hertog J, Kimata K, Zivkovic D. Heparan sulfate 6-O-sulfotransferase is essential for muscle development in Zebrafish. J Biol Chem. 2003 Aug 15;278(33):31118-27. Epub 2003 Jun 01..

Homozygosity Mapping and Candidate Prioritization Identify Mutations, Missed by Whole-Exome Sequencing, in SMOC2, Causing Major Dental Developmental Defects

Authors:
Bloch-Zupan A, Jamet X, Etard C, Laugel V, Muller J, Geoffroy V, Strauss J-P, Pelletier V, Marion V, Poch O, Strahle U, Stoetzel C, Hélène Dollfus H
Citation:
Am J Hum Genet. 2011 December 9; 89(6): 773–781. doi: 10.1016/j.ajhg.2011.11.002
Epub:
Not Epub
Abstract:
Inherited dental malformations constitute a clinically and genetically heterogeneous group of disorders. Here, we report on a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bloch-Zupan A, Jamet X, Etard C, Laugel V, Muller J, Geoffroy V, Strauss J-P, Pelletier V, Marion V, Poch O, Strahle U, Stoetzel C, Hélène Dollfus H. Homozygosity Mapping and Candidate Prioritization Identify Mutations, Missed by Whole-Exome Sequencing, in SMOC2, Causing Major Dental Developmental Defects. Am J Hum Genet. 2011 December 9; 89(6): 773–781. doi: 10.1016/j.ajhg.2011.11.002.

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