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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia

Authors:
Blechman J, Borodovsky N, Eisenberg M, Nabel-Rosen H, Grimm J, Levkowitz G
Citation:
Development. 2007 Dec;134(24):4417-26. Epub 2007 Nov 14
Epub:
Not Epub
Abstract:
In the developing hypothalamus, a variety of neurons are generated adjacent to each other in a highly coordinated, but poorly...
Organism or Cell Type:
zebrafish
Citation Extract:
Blechman J, Borodovsky N, Eisenberg M, Nabel-Rosen H, Grimm J, Levkowitz G. Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia. Development. 2007 Dec;134(24):4417-26. Epub 2007 Nov 14.

Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development

Authors:
Blaschke RJ, Hahurij ND, Kuijper S, Just S, Wisse LJ, Deissler K, Maxelon T, Anastassiadis K, Spitzer J, Hardt SE, Scholer H, Feitsma H, Rottbauer W, Blum M, Meijlink F, Rappold G, Gittenberger-de Groot AC
Citation:
Circulation. 2007 Apr 10;115(14):1830-8. Epub 2007 Mar 19
Epub:
Not Epub
Abstract:
BACKGROUND: Identifying molecular pathways regulating the development of pacemaking and coordinated heartbeat is crucial for a...
Organism or Cell Type:
zebrafish
Citation Extract:
Blaschke RJ, Hahurij ND, Kuijper S, Just S, Wisse LJ, Deissler K, Maxelon T, Anastassiadis K, Spitzer J, Hardt SE, Scholer H, Feitsma H, Rottbauer W, Blum M, Meijlink F, Rappold G, Gittenberger-de Groot AC. Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development. Circulation. 2007 Apr 10;115(14):1830-8. Epub 2007 Mar 19.

The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling

Authors:
Borgal L, Habbig S, Hatzold J, Liebau MC, Dafinger C, Sacarea I, Hammerschmidt M, Benzing T, Schermer B
Citation:
J Biol Chem. 2012 Jul 20;287(30):25370-80. doi: 10.1074/jbc.M112.385658. Epub 2012 May 31
Epub:
Not Epub
Abstract:
Nephronophthisis (NPH) is an autosomal-recessive cystic kidney disease and represents the most common genetic cause for end-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Borgal L, Habbig S, Hatzold J, Liebau MC, Dafinger C, Sacarea I, Hammerschmidt M, Benzing T, Schermer B. The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling. J Biol Chem. 2012 Jul 20;287(30):25370-80. doi: 10.1074/jbc.M112.385658. Epub 2012 May 31.

The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization

Authors:
Bonacci G, Fletcher J, Devani M, Dwivedi H, Keller R, Chang C
Citation:
Dev Biol. 2012 Apr 1;364(1):42-55. doi: 10.1016/j.ydbio.2012.01.008. Epub 2012 Jan 18
Epub:
Not Epub
Abstract:
Coordinated cell movements are crucial for vertebrate gastrulation and are controlled by multiple signals. Although many...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Bonacci G, Fletcher J, Devani M, Dwivedi H, Keller R, Chang C. The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization. Dev Biol. 2012 Apr 1;364(1):42-55. doi: 10.1016/j.ydbio.2012.01.008. Epub 2012 Jan 18.

The E3 ubiquitin ligase skp2 regulates neural differentiation independent from the cell cycle

Authors:
Boix-Perales H, Horan I, Wise H, Lin HR, Chuang LC, Yew PR, Philpott A
Citation:
Neural Develop. 2007 Dec 14;2:27
Epub:
Not Epub
Abstract:
BACKGROUND: The SCFskp2 complex is an E3 ubiquitin ligase that is known to target a number of cell cycle regulators, including...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Boix-Perales H, Horan I, Wise H, Lin HR, Chuang LC, Yew PR, Philpott A. The E3 ubiquitin ligase skp2 regulates neural differentiation independent from the cell cycle. Neural Develop. 2007 Dec 14;2:27.

The Metabolic Regulator PGC-1α Directly Controls the Expression of the Hypothalamic Neuropeptide Oxytocin

Authors:
Blechman J, Amir-Zilberstein L, Gutnick A, Ben-Dor S, Levkowitz G
Citation:
J Neurosci. 2011;31(42):14835-14840 doi:10.1523/JNEUROSCI.1798-11.2011
Epub:
Not Epub
Abstract:
The transcriptional coactivator PGC-1α is a key regulator of cellular energy expenditure in peripheral tissues. Recent studies...
Organism or Cell Type:
zebrafish
Citation Extract:
Blechman J, Amir-Zilberstein L, Gutnick A, Ben-Dor S, Levkowitz G. The Metabolic Regulator PGC-1α Directly Controls the Expression of the Hypothalamic Neuropeptide Oxytocin. J Neurosci. 2011;31(42):14835-14840 doi:10.1523/JNEUROSCI.1798-11.2011.

The RNA binding protein CPEB regulates dendrite morphogenesis and neuronal circuit assembly in vivo

Authors:
Bestman JE, Cline HT
Citation:
Proc Natl Acad Sci U S A. 2008 Dec 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Visual system development requires experience-dependent mechanisms that regulate neuronal structure and function, including...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bestman JE, Cline HT. The RNA binding protein CPEB regulates dendrite morphogenesis and neuronal circuit assembly in vivo. Proc Natl Acad Sci U S A. 2008 Dec 12. [Epub ahead of print].

The Role of the Aryl Hydrocarbon Receptor Pathway in Mediating Synergistic Developmental Toxicity of Polycyclic Aromatic Hydrocarbons to Zebrafish

Authors:
Billiard S, Timme-Laragy AR, Wassenberg DM, Cockman C, Di Giulio RT
Citation:
Toxicol Sci. 2006 Aug;92(2):526-36. Epub 2006 May 9
Epub:
Not Epub
Abstract:
Planar halogenated aromatic hydrocarbons (pHAH), such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin), show strong binding...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Billiard S, Timme-Laragy AR, Wassenberg DM, Cockman C, Di Giulio RT. The Role of the Aryl Hydrocarbon Receptor Pathway in Mediating Synergistic Developmental Toxicity of Polycyclic Aromatic Hydrocarbons to Zebrafish. Toxicol Sci. 2006 Aug;92(2):526-36. Epub 2006 May 9.

The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling

Authors:
Bottcher RT, Pollet N, Delius H, Niehrs C
Citation:
Nat Cell Biol. 2004 Jan;6(1):38-44.
Epub:
Not Epub
Abstract:
Fibroblast growth factors (FGFs) signal through high-affinity tyrosine kinase receptors to regulate a diverse range of cellular...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bottcher RT, Pollet N, Delius H, Niehrs C. The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling. Nat Cell Biol. 2004 Jan;6(1):38-44..

Tip-1 induces filopodia growth and is important for gastrulation movements during zebrafish development

Authors:
Besser J, Leito JT, van der Meer DL, Bagowski CP
Citation:
Dev Growth Differ. 2007 Apr;49(3):205-14
Epub:
Not Epub
Abstract:
Wnt signaling is essential during animal development and also plays important roles in pathological conditions. Two mayor...
Organism or Cell Type:
zebrafish
Citation Extract:
Besser J, Leito JT, van der Meer DL, Bagowski CP. Tip-1 induces filopodia growth and is important for gastrulation movements during zebrafish development. Dev Growth Differ. 2007 Apr;49(3):205-14.

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