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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery

Authors:
Bai H, Xue X, Hou Z, Zhou Y, Meng J, Luo X
Citation:
Curr Drug Discov Technol. 2010 Sep 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The nightmare of multi-drug resistant bacteria will still haunt if no panacea is ever found. Efforts on seeking desirable...
Organism or Cell Type:
Bacteria (review)
Citation Extract:
Bai H, Xue X, Hou Z, Zhou Y, Meng J, Luo X. Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery. Curr Drug Discov Technol. 2010 Sep 14. [Epub ahead of print].

Antisense oligonucleotides targeted to the p53 gene modulate rat liver regeneration

Authors:
Arora V, Iversen PL
Citation:
Drug Metab. And Disp. 2000. 28(2):131-138
Epub:
Not Epub
Abstract:
The rapidly proliferating cells of the regenerating liver after partial hepatectomy (PH) present a reproducible in vivo model...
Delivery Method:
in vivo: injection
Organism or Cell Type:
rats, Sprague Dawley
Citation Extract:
Arora V, Iversen PL. Antisense oligonucleotides targeted to the p53 gene modulate rat liver regeneration. Drug Metab. And Disp. 2000. 28(2):131-138.

ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1

Authors:
Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, Rogachev I, Wan W, Murphy PM, Farber SA, Carmel L, Shelness GS, Iruela-Arispe ML, Weinstein BM, Yaniv K
Citation:
Nat Med. 2012;[Epub ahead of print] doi:10.1038/nm.2759
Epub:
Not Epub
Abstract:
Despite the clear major contribution of hyperlipidemia to the prevalence of cardiovascular disease in the developed world, the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, Rogachev I, Wan W, Murphy PM, Farber SA, Carmel L, Shelness GS, Iruela-Arispe ML, Weinstein BM, Yaniv K. ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nat Med. 2012;[Epub ahead of print] doi:10.1038/nm.2759.

Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats

Authors:
Arora V, Knapp DC, Reddy MT, Weller DD, Iversen PL.
Citation:
J Pharm Sci. 2002 Apr;91(4):1009-18
Epub:
Not Epub
Abstract:
Antisense phosphorodiamidate Morpholino oligomers (PMO) are resistant to degradation by cellular hydrolases, DNases, RNases,...
Delivery Method:
in vivo: injection
Organism or Cell Type:
rats, Sprague Dawley
Citation Extract:
Arora V, Knapp DC, Reddy MT, Weller DD, Iversen PL.. Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats. J Pharm Sci. 2002 Apr;91(4):1009-18.

Brain selective transgene expression in zebrafish using an NRSE derived motif

Authors:
Bergeron SA, Hannan MC, Codore H, Fero K, Li G, Moak ZB, Yokogawa T, Burgess HA
Citation:
Front Neur Circuits. 2012;6(00110). doi:10.3389/fncir.2012.00110
Epub:
Not Epub
Abstract:
Transgenic technologies enable the manipulation and observation of circuits controlling behavior by permitting expression of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bergeron SA, Hannan MC, Codore H, Fero K, Li G, Moak ZB, Yokogawa T, Burgess HA. Brain selective transgene expression in zebrafish using an NRSE derived motif. Front Neur Circuits. 2012;6(00110). doi:10.3389/fncir.2012.00110.

Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish

Authors:
Bergeron SA, Tyurina OV, Miller E, Bagas A, Karlstrom RO
Citation:
Development. 2011 Jan;138(1):75-85. Epub 2010 Nov 29
Epub:
Not Epub
Abstract:
The transmembrane protein Brother of Cdo (Boc) has been implicated in Shh-mediated commissural axon guidance, and can both...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bergeron SA, Tyurina OV, Miller E, Bagas A, Karlstrom RO. Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish. Development. 2011 Jan;138(1):75-85. Epub 2010 Nov 29.

c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity

Authors:
Arora V, Knapp DC, Smith BL, Statdfield ML, Stein DA, Reddy MT, Weller DD, Iversen PL
Citation:
Exp Ther 2000 Mar 292(3):921-8
Epub:
Not Epub
Abstract:
Expression of c-myc protein is associated with cell proliferation. The present study uses antisense oligomers to inhibit c-myc...
Delivery Method:
Injection
Organism or Cell Type:
rats, Sprague Dawley
Citation Extract:
Arora V, Knapp DC, Smith BL, Statdfield ML, Stein DA, Reddy MT, Weller DD, Iversen PL. c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity. Exp Ther 2000 Mar 292(3):921-8.

Cadherin-2 participates in the morphogenesis of the zebrafish inner ear

Authors:
Babb-Clendenon S, Shen YC, Liu Q, Turner KE, Mills MS, Cook GW, Miller CA, Gattone VH 2nd, Barald KF, Marrs JA
Citation:
J Cell Sci. 2006 Dec 15;119(Pt 24):5169-77
Epub:
Not Epub
Abstract:
Molecular mechanisms that control inner ear morphogenesis from the placode to the three-dimensional functional organ are not...
Organism or Cell Type:
zebrafish
Citation Extract:
Babb-Clendenon S, Shen YC, Liu Q, Turner KE, Mills MS, Cook GW, Miller CA, Gattone VH 2nd, Barald KF, Marrs JA. Cadherin-2 participates in the morphogenesis of the zebrafish inner ear. J Cell Sci. 2006 Dec 15;119(Pt 24):5169-77.

Cadherin2 (N-cadherin) plays an essential role in zebrafish cardiovascular development

Authors:
Bagatto B, Francl J, Liu B, Liu Q
Citation:
BMC Dev Biol. 2006 May 23;6:23
Epub:
Not Epub
Abstract:
ABSTRACT: Cadherins are cell surface adhesion molecules that play important roles in development of vertebrate tissues and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bagatto B, Francl J, Liu B, Liu Q. Cadherin2 (N-cadherin) plays an essential role in zebrafish cardiovascular development. BMC Dev Biol. 2006 May 23;6:23.

CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis

Authors:
Bertrand JY, Kim AD, Teng S, Traver D
Citation:
Development. 2008 May;135(10):1853-62. Epub 2008 Apr 16
Epub:
Not Epub
Abstract:
Development of the vertebrate blood lineages is complex, with multiple waves of hematopoietic precursors arising in different...
Organism or Cell Type:
zebrafish
Citation Extract:
Bertrand JY, Kim AD, Teng S, Traver D. CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis. Development. 2008 May;135(10):1853-62. Epub 2008 Apr 16.

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