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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Transforming growth factor-β1/Thrombospondin-1/CD47 axis mediates dysfunction in CD34+ cells derived from diabetic older adults
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Citation:
Eur J Pharmacol. 2022 Feb 23;920:174842. doi: 10.1016/j.ejphar.2022.174842. Online ahead of print Epub:
Not Epub Abstract:
Aging with diabetes is associated with impaired vasoprotective functions and decreased nitric oxide (NO) generation in CD34+... Organism or Cell Type:
cell culture: CD34+ (diabetic/non-diabetic) Citation Extract: Jahan J, Monte de Oca I, Meissner B, Joshi S, Maghrabi A, Quiroz-Olvera J, Lopez-Yang C, Bartelmez SH, Garcia C, Jarajapu YP. Transforming growth factor-β1/Thrombospondin-1/CD47 axis mediates dysfunction in CD34+ cells derived from diabetic older adults. Eur J Pharmacol. 2022 Feb 23;920:174842. doi: 10.1016/j.ejphar.2022.174842. Online ahead of print. |
In Vitro Delivery of PMOs in Myoblasts by Electroporation
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Citation:
Methods Mol Biol. 2022;2434:191-205. doi: 10.1007/978-1-0716-2010-6_12 Epub:
Not Epub Abstract:
Antisense oligonucleotides (AONs) are small synthetic molecules of therapeutic interest for a variety of human disease. Their... Delivery Method:
electroporation Organism or Cell Type:
cell culture: myoblasts Citation Extract: Goossens R, Aartsma-Rus A. In Vitro Delivery of PMOs in Myoblasts by Electroporation. Methods Mol Biol. 2022;2434:191-205. doi: 10.1007/978-1-0716-2010-6_12. |
Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen
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Citation:
Methods Mol Biol. 2022;2434:129-141. Humana, New York, NY. doi:10.1007/978-1-0716-2010-6_8 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) offer great promise as therapeutic agents for translation blocking or splice... Delivery Method:
peptide-linked Citation Extract: Palacio-Castañeda V, Brock R, Verdurmen WPR. Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen. Methods Mol Biol. 2022;2434:129-141. Humana, New York, NY. doi:10.1007/978-1-0716-2010-6_8. |
Zygotic hypoxia-inducible factor alpha regulates spicule elongation in the sea urchin embryo
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Citation:
Dev Biol. 2022 Feb 17;484:63-74. doi: 10.1016/j.ydbio.2022.02.004. Online ahead of print Epub:
Not Epub Abstract:
Sea urchin larval skeletons are produced by skeletogenic primary mesenchyme cells (PMCs), which migrate to form two... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Chang WL, Su YH. Zygotic hypoxia-inducible factor alpha regulates spicule elongation in the sea urchin embryo. Dev Biol. 2022 Feb 17;484:63-74. doi: 10.1016/j.ydbio.2022.02.004. Online ahead of print. |
Development of DG9 peptide-conjugated single- and multi-exon skipping therapies for the treatment of Duchenne muscular dystrophy
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Citation:
Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2112546119. doi: 10.1073/pnas.2112546119 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is primarily caused by out-of-frame deletions in the dystrophin gene. Exon skipping using... Delivery Method:
peptide-linked Organism or Cell Type:
mice hDMDdel52;mdx Citation Extract: Lim KRQ, Woo S, Melo D, Huang Y, Dzierlega K, Shah MNA, Aslesh T, Roshmi RR, Echigoya Y, Maruyama R, Moulton HM, Yokota T. Development of DG9 peptide-conjugated single- and multi-exon skipping therapies for the treatment of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2112546119. doi: 10.1073/pnas.2112546119. |
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders
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Citation:
Science. 2022 Feb 18;375(6582):eabm4459. doi:10.1126/science.abm4459 Epub:
Not Epub Abstract:
The blood-brain barrier (BBB) protects the central nervous system (CNS) from harmful blood-borne factors. Although BBB... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Martin M, Vermeiren S, Bostaille N, Eubelen M, Spitzer D, Vermeersch M, Profaci CP, Pozuelo E, Toussay X, Vanhollebeke B. Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders. Science. 2022 Feb 18;375(6582):eabm4459. doi:10.1126/science.abm4459. |
Label-Free Detection of Morpholino-DNA Hybridization Using a Silicon Photonics Suspended Slab Micro-Ring Resonator
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Citation:
IEEE Photon J. 2021;14(4):6600809. doi:10.1109/JPHOT.2021.3098680 Epub:
Not Epub Abstract:
In this study, deoxyribonucleic acid (DNA) hybridization was demonstrated using a suspended silicon photonics micro-ring... Citation Extract: Yousuf S, Kim J, Orozaliev A, Dahlem MS, Song Y-A, Viegas J. Label-Free Detection of Morpholino-DNA Hybridization Using a Silicon Photonics Suspended Slab Micro-Ring Resonator. IEEE Photon J. 2021;14(4):6600809. doi:10.1109/JPHOT.2021.3098680. |
Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells
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Citation:
Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2122030119. doi: 10.1073/pnas.2122030119 Epub:
Yes Abstract:
Tension of the actomyosin cell cortex plays a key role in determining cell-cell contact growth and size. The level of cortical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Slováková J, Sikora M, Arslan FN, Caballero-Mancebo S, Krens SFG, Kaufmann WA, Merrin J, Heisenberg CP. Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2122030119. doi: 10.1073/pnas.2122030119. |
A female carrier of spinal and bulbar muscular atrophy diagnosed with DNAJB6-related distal myopathy
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Citation:
J Hum Genet. 2022 Feb 15. doi: 10.1038/s10038-022-01022-3. Online ahead of print Epub:
Not Epub Abstract:
Mutations in the DNAJB6 gene cause limb girdle muscular dystrophy D1 (LGMD D1) and distal myopathy with rimmed vacuoles. With... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu L, Geng H, Lv X, Wang G, Yan C, Zhang D, Lin P. A female carrier of spinal and bulbar muscular atrophy diagnosed with DNAJB6-related distal myopathy. J Hum Genet. 2022 Feb 15. doi: 10.1038/s10038-022-01022-3. Online ahead of print. |
Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism
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Citation:
Molecules. 2022;27(4):1290. doi:10.3390/molecules27041290 Epub:
Not Epub Abstract:
Zebrafish (ZF; Danio rerio) larvae have become a popular in vivo model in drug metabolism studies. Here, we investigated the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Park YM, Dahlem C, Meyer MR, Kiemer AK, Müller R, Herrmann J. Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism. Molecules. 2022;27(4):1290. doi:10.3390/molecules27041290. |