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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12179 scientific papers returned from the database with the search filters currently being used below.
There are 12179 scientific papers returned from the database with the search filters currently being used below.
LIM Homeobox 9 Knockdown by Morpholino does not Affect Zebrafish Retinal Development
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Citation:
Bio Open. 2021:bio.056382 doi:10.1242/bio.056382 Epub:
Not Epub Abstract:
LIM homeobox 9 (Lhx9) is a member of the LIM homeodomain transcription factor family, which expresses and functions in various... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guo R, Li F, Lu M, Ge K, Gan L, Sheng D. LIM Homeobox 9 Knockdown by Morpholino does not Affect Zebrafish Retinal Development. Bio Open. 2021:bio.056382 doi:10.1242/bio.056382. |
Transformed notochordal cells trigger chronic wounds in zebrafish, destabilizing the vertebral column and bone homeostasis
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Citation:
Dis Model Mech. 2021 Mar 1;14(3):dmm047001. doi: 10.1242/dmm.047001. Epub 2021 Mar 19. PMID: 33579726; PMCID: PMC7988777 Epub:
Yes Abstract:
Notochordal cells play a pivotal role in vertebral column patterning, contributing to the formation of the inner architecture... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: López-Cuevas P, Deane L, Yang Y, Hammond CL, Kague E. Transformed notochordal cells trigger chronic wounds in zebrafish, destabilizing the vertebral column and bone homeostasis. Dis Model Mech. 2021 Mar 1;14(3):dmm047001. doi: 10.1242/dmm.047001. Epub 2021 Mar 19. PMID: 33579726; PMCID: PMC7988777. |
Chemokine-biased robust self-organizing polarization of migrating cells in vivo
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Citation:
Proc Natl Acad Sci USA. 2021;118(7);e2018480118 doi:10.1073/pnas.2018480118 Epub:
Not Epub Abstract:
To study the mechanisms controlling front-rear polarity in migrating cells, we used zebrafish primordial germ cells (PGCs) as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Olguin-Olguin A, Aalto A, Maugis B, Boquet-Pujadas A, Hoffmann D, Ermlich L, Betz T, Gov NS, Reichman-Fried M, Raz E. Chemokine-biased robust self-organizing polarization of migrating cells in vivo. Proc Natl Acad Sci USA. 2021;118(7);e2018480118 doi:10.1073/pnas.2018480118. |
Retinol Binding Protein 1 Affects Xenopus Anterior Neural Development via All-trans Retinoic Acid Signalling
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Citation:
Dev Dyn. 2021 Feb 11. doi: 10.1002/dvdy.313. Online ahead of print Epub:
Not Epub Abstract:
Background: Retinol binding protein 1 (Rbp1) acts as an intracellular regulator of vitamin A metabolism and retinoid transport... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Flach H, Basten T, Schreiner C, Dietmann P, Greco S, Nies L, Roßmanith N, Walter S, Kühl M, Kühl SJ. Retinol Binding Protein 1 Affects Xenopus Anterior Neural Development via All-trans Retinoic Acid Signalling. Dev Dyn. 2021 Feb 11. doi: 10.1002/dvdy.313. Online ahead of print. |
sGC activity and regulation of blood flow in a Zebrafish model system
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Citation:
Front Physiol. 2021;[provisional] doi: 10.3389/fphys.2021.633171 Epub:
Yes Abstract:
Soluble guanylyl cyclase (sGC) protein is a heterodimer formed by two subunits encoded by the GUCY1A1 and GUCY1B1 genes. The... Organism or Cell Type:
zebrafish Citation Extract: Vishnolia KK, Rakovic A, Hoene C, Tarhbalouti K, Aherrahrou Z, Erdmann J. sGC activity and regulation of blood flow in a Zebrafish model system. Front Physiol. 2021;[provisional] doi: 10.3389/fphys.2021.633171. |
Computational simulations of the 4D micro-circulatory network in zebrafish tail amputation and regeneration
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Citation:
J R Soc Interface. 2022 Feb;19(187):20210898. doi: 10.1098/rsif.2021.0898. Epub 2022 Feb 16. PMID: 35167770; PMCID: PMC8848759 Epub:
Not Epub Abstract:
Wall shear stress (WSS) contributes to the mechanotransduction underlying microvascular development and regeneration. Using... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roustaei M, In Baek K, Wang Z, Cavallero S, Satta S, Lai A, O'Donnell R, Vedula V, Ding Y, Marsden AL, Hsiai TK. Computational simulations of the 4D micro-circulatory network in zebrafish tail amputation and regeneration. J R Soc Interface. 2022 Feb;19(187):20210898. doi: 10.1098/rsif.2021.0898. Epub 2022 Feb 16. PMID: 35167770; PMCID: PMC8848759. |
Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning
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Citation:
Nat Methods. 2021. doi:10.1038/s41592-021-01058-x Epub:
Not Epub Abstract:
Light-field microscopy has emerged as a technique of choice for high-speed volumetric imaging of fast biological processes.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Z, Zhu L, Zhang H, Li G, Yi C, Li Y, Yang Y, Ding Y, Zhen M, Gao S, Hsiai TK, Fei P. Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning. Nat Methods. 2021. doi:10.1038/s41592-021-01058-x. |
Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish
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Citation:
Front Cell Devel Biol. 2021;9:34. doi:10.3389/fcell.2021.627409 Epub:
Not Epub Abstract:
Mutations in the CCN6 (WISP3) gene are linked with a debilitating musculoskeletal disorder, termed progressive pseudorheumatoid... Delivery Method:
injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Sengupta A, Padhan DK, Ganguly A, Sen M. Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish. Front Cell Devel Biol. 2021;9:34. doi:10.3389/fcell.2021.627409. |
Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation
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Citation:
Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w Epub:
Not Epub Abstract:
Neurofibromatosis Type 1 (NF1) is a genetic condition affecting approximately 1:3500 persons worldwide. The NF1 gene codes for... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: PC12 Citation Extract: Biayna J, Mazuelas H, Gel B, Terribas E, Dumbovic G, Rosas I, Fernández-Rodriguez J, Blanco I, Castellanos E, Carrió M, Lazaro C, Serra E. Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation. Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w. |
Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides
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Citation:
Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disease caused by frameshift or nonsense mutations in the DMD gene... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture:CXMDJ immortalized myoblasts Citation Extract: Tone Y, Mamchaoui K, Tsoumpra MK, Hashimoto Y, Terada R, Maruyama R, Gait MJ, Arzumanov AA, McClorey G, Imamura M, Takeda S, Yokota T, Wood MJA, Mouly V, Aoki Y. Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides. Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print. |
