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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Patterning of phase-separated condensates by Dnd1 controls cell fate
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.20.512863 Epub:
Not Epub Abstract:
Germ granules, condensates of phase-separated RNA and protein, are essential for germline development, but how these molecules... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Westerich KJ, Tarbashevich K, Gupta A, Zhu M, Hull K, Daniel Romo, Gross-Thebing T, Raz E. Patterning of phase-separated condensates by Dnd1 controls cell fate. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.20.512863 . |
Alternative splicing of apoptosis genes promotes human T cell survival
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Citation:
eLife. 2022;11:e80953. doi:10.7554/eLife.80953 Epub:
Not Epub Abstract:
Alternative splicing occurs in the vast majority of human genes, giving rise to distinct mRNA and protein isoforms. We, and... Delivery Method:
electroporation Organism or Cell Type:
cell culture: Jurkat Citation Extract: Blake D, Radens CM, Ferretti MB, Gazzara MR, Lynch KW. Alternative splicing of apoptosis genes promotes human T cell survival. eLife. 2022;11:e80953. doi:10.7554/eLife.80953. |
Lmo7 recruits myosin II heavy chain to regulate actomyosin contractility and apical domain size in Xenopus ectoderm
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Citation:
Development. 2022 May 15;149(10):dev200236. doi: 10.1242/dev.200236. Epub 2022 May 16 Epub:
Not Epub Abstract:
Apical constriction, or a reduction in size of the apical domain, underlies many morphogenetic events during development.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Matsuda M, Chu CW, Sokol SY. Lmo7 recruits myosin II heavy chain to regulate actomyosin contractility and apical domain size in Xenopus ectoderm. Development. 2022 May 15;149(10):dev200236. doi: 10.1242/dev.200236. Epub 2022 May 16. |
Functional testing of BMP pathway variants identified on whole exome sequencing in a patient with delayed-onset fibrodysplasia ossificans progressiva (FOP) using ACVR1R206H -specific human cellular and zebrafish models
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Citation:
J Bone Miner Res. 2022 Sep 25. doi: 10.1002/jbmr.4711. Online ahead of print Epub:
Not Epub Abstract:
Bone morphogenetic protein (BMP) signaling is critical in skeletal development. Over-activation can trigger heterotopic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wentworth KL, Lalonde RL, Groppe JC, Brewer N, Moody T, Hansberry S, Taylor K, Shore EM, Kaplan FS, Pignolo RJ, Yelick PC, Hsiao EC. Functional testing of BMP pathway variants identified on whole exome sequencing in a patient with delayed-onset fibrodysplasia ossificans progressiva (FOP) using ACVR1R206H -specific human cellular and zebrafish models. J Bone Miner Res. 2022 Sep 25. doi: 10.1002/jbmr.4711. Online ahead of print. |
Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona
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Citation:
Development. 2022;149(21):dev200215. doi:10.1242/dev.200215 Epub:
Not Epub Abstract:
Ventral tail bending, which is transient but pronounced, is found in many chordate embryos and constitutes an interesting model... Delivery Method:
microinjection Organism or Cell Type:
Ciona robusta (ascidian) Citation Extract: Kogure YS, Muraoka H, Koizumi WC, Gelin-alessi R, Godard B, Oka K, Heisenberg C-P, Hotta K. Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona. Development. 2022;149(21):dev200215. doi:10.1242/dev.200215. |
NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart
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Citation:
Nat Commun. 2022;13:6209. doi:10.1038/s41467-022-33658-2 Epub:
Not Epub Abstract:
To adapt to changing hemodynamic demands, regulatory mechanisms modulate actin-myosin-kinetics by calcium-dependent and -... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Müller M, Eghbalian R, Boeckel J-N, Frese KS, Haas J, Kayvanpour E, Sedaghat-Hamedani F, Lackner MK, Tugrul OF, Ruppert T, Tappu R, Martins BD, Kneuer JM, Piekarek A, Herch S, Schudy S, Keller A, Grammes N, Bischof C, Klinke A, Cardoso-Moreira M, Kaessmann H, Katus HA, Frey N, Steinmetz LM, Meder B. NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart. Nat Commun. 2022;13:6209. doi:10.1038/s41467-022-33658-2. |
Recent reconfiguration of an ancient developmental gene regulatory network in Heliocidaris sea urchins
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Citation:
Nat Ecol Evol. 2022;[Epub] doi:10.1038/s41559-022-01906-9 Epub:
Not Epub Abstract:
Changes in developmental gene regulatory networks (dGRNs) underlie much of the diversity of life, but the evolutionary... Delivery Method:
microinjection Organism or Cell Type:
Heliocidaris erythrogramma (sea urchin) Citation Extract: Davidson PL, Guo H, Swart JS, Massri AJ, Edgar A, Wang L, Berrio A, Devens HR, Koop D, Cisternas P, Zhang H, Zhang Y, Byrne M, Fan G, Wray GA. Recent reconfiguration of an ancient developmental gene regulatory network in Heliocidaris sea urchins. Nat Ecol Evol. 2022;[Epub] doi:10.1038/s41559-022-01906-9. |
Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells
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Citation:
Adv Sci (Weinh). 2022 Oct 18:e2203631. doi: 10.1002/advs.202203631. Online ahead of print Epub:
Not Epub Abstract:
Maintenance and differentiation of germline stem and progenitor cells (GSPCs) is important for sexual reproduction. Here, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang R, Tu YX, Ye D, Gu Z, Chen ZX, Sun Y. Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells. Adv Sci (Weinh). 2022 Oct 18:e2203631. doi: 10.1002/advs.202203631. Online ahead of print. |
5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons
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Citation:
Proc Nat Acad Sci USA. 2022;119(42):e2123338119 doi:10.1073/pnas.2123338119 Epub:
Not Epub Abstract:
5-methylcytosine (m5C) is one of the most prevalent modifications of RNA, playing important roles in RNA metabolism, nuclear... Delivery Method:
Vivo-Morpholino intranasal & i.v. injection Organism or Cell Type:
mice Citation Extract: Zhang Y, Zhang L-S, Dai Q, Chen P, Lu M, Kairis EL, Murugaiah V, Xu J, Shukla RK, Liang X, Zou Z, Cormet-Boyaka E, Qiu J, Peeples ME, Sharma A, He C, Li J. 5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons. Proc Nat Acad Sci USA. 2022;119(42):e2123338119 doi:10.1073/pnas.2123338119. |
Brain milieu induces early microglial maturation through the BAX-Notch axis
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Citation:
Nat Commun. 2022;13(1):6117. doi:10.1038/s41467-022-33836-2 Epub:
Not Epub Abstract:
Microglia are derived from primitive myeloid cells and gain their early identity in the embryonic brains. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao F, He J, Tang J, Cui N, Shi Y, Li Z, Liu S, Wang Y, Ma M, Zhao C, Luo L, Li L. Brain milieu induces early microglial maturation through the BAX-Notch axis. Nat Commun. 2022;13(1):6117. doi:10.1038/s41467-022-33836-2. |