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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish
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Citation:
Nat Commun. 2022 Nov 11;13(1):6841. doi: 10.1038/s41467-022-34354-x Epub:
Not Epub Abstract:
Vesicle biogenesis, trafficking and signaling via Endoplasmic reticulum-Golgi network support essential developmental processes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fasano G, Muto V, Radio FC, Venditti M, Mosaddeghzadeh N, Coppola S, Paradisi G, Zara E, Bazgir F, Ziegler A, Chillemi G, Bertuccini L, Tinari A, Vetro A, Pantaleoni F, Pizzi S, Conti LA, Petrini S, Bruselles A, Prandi IG, Mancini C, Chandramouli B, Barth M, Bris C, Milani D, Selicorni A, Macchiaiolo M, Gonfiantini MV, Bartuli A, Mariani R, Curry CJ, Guerrini R, Slavotinek A, Iascone M, Dallapiccola B, Ahmadian MR, Lauri A, Tartaglia M. Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish. Nat Commun. 2022 Nov 11;13(1):6841. doi: 10.1038/s41467-022-34354-x. |
The circadian rhythm regulates branched-chain amino acids metabolism in fast muscle of Chinese perch (Siniperca chuatsi) during short-term fasting by Clock-KLF15-Bcat2 pathway
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Citation:
Br J Nutr. 2022 Nov 14:1-31. doi: 10.1017/S0007114522003646. Online ahead of print Epub:
Not Epub Abstract:
As an internal time keeping mechanism, circadian rhythm plays crucial role in maintaining homeostasis when in response to... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Siniperca chuatsi (Chinese perch) Citation Extract: Zhu X, Liu J, Cai M, Bao L, Pan Y, Wu P, Chu W, Zhang J. The circadian rhythm regulates branched-chain amino acids metabolism in fast muscle of Chinese perch (Siniperca chuatsi) during short-term fasting by Clock-KLF15-Bcat2 pathway. Br J Nutr. 2022 Nov 14:1-31. doi: 10.1017/S0007114522003646. Online ahead of print. |
A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience
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Citation:
Nat Comm. 2022;13:6805. doi:10.1038/s41467-022-34450-y Epub:
Not Epub Abstract:
Cells adapt to cold by increasing levels of unsaturated phospholipids and membrane fluidity through conserved homeostatic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang C, Wang B, Pandey T, Long Y, Zhang J, Oh F, Sima J, Guo R, Liu Y, Zhang C, Mukherjee S, Bassik M, Lin W, Deng H, Vale G, McDonald J, Shen K, Ma DK. A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience. Nat Comm. 2022;13:6805. doi:10.1038/s41467-022-34450-y. |
Planar polarized force propagation integrates cell behavior and tissue morphogenesis during convergent extension
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.11.08.515701 Epub:
Not Epub Abstract:
Convergent extension (CE) is an evolutionarily conserved developmental process whereby polarized collective cell movements... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Weng S, Huebner R, Devitt C, Nyaoga B, Alvarado J, Wallingford J. Planar polarized force propagation integrates cell behavior and tissue morphogenesis during convergent extension. bioRxiv. 2022;[preprint] doi:10.1101/2022.11.08.515701 . |
Syntaxin 4 is essential for hearing in human and zebrafish
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Citation:
Hum Mol Genet. 2022 Nov 10:ddac257. doi: 10.1093/hmg/ddac257. Online ahead of print Epub:
Not Epub Abstract:
Congenital hearing impairment is a genetically highly heterogenous disorder in which prompt recognition and intervention are... Organism or Cell Type:
zebrafish Citation Extract: Schrauwen I, Ghaffar A, Bharadwaj T, Shah K, Rehman S, Acharya A, Liaqat K, Lin NS, Everard JL, Khan A, Ahmed ZM, Ahmad W, Riazuddin S, Leal SM. Syntaxin 4 is essential for hearing in human and zebrafish. Hum Mol Genet. 2022 Nov 10:ddac257. doi: 10.1093/hmg/ddac257. Online ahead of print. |
The apical ciliary adhesion complex is established at the basal foot of motile cilia and depends on the microtubule network
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Citation:
Sci Rep. 2022 Nov 8;12(1):19028. doi: 10.1038/s41598-022-22871-0 Epub:
Not Epub Abstract:
The Ciliary Adhesion (CA) complex forms in close association with the basal bodies of cilia during the early stages of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Chatzifrangkeskou M, Skourides PA. The apical ciliary adhesion complex is established at the basal foot of motile cilia and depends on the microtubule network. Sci Rep. 2022 Nov 8;12(1):19028. doi: 10.1038/s41598-022-22871-0. |
Acupuncture Needle-Based Transistor Neuroprobe for In Vivo Monitoring of Neurotransmitter
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Citation:
Small. 2022 Dec;18(52):e2204142. doi: 10.1002/smll.202204142. Epub 2022 Nov 7. PMID: 36344461 Epub:
Not Epub Abstract:
Chemical communication via neurotransmitters is central to brain functions. Nevertheless, in vivo real-time monitoring of... Organism or Cell Type:
rat Citation Extract: Zhou Y, Liu B, Lei Y, Tang L, Li T, Yu S, Zhang GJ, Li YT. Acupuncture Needle-Based Transistor Neuroprobe for In Vivo Monitoring of Neurotransmitter. Small. 2022 Dec;18(52):e2204142. doi: 10.1002/smll.202204142. Epub 2022 Nov 7. PMID: 36344461. |
osr1 Maintains Renal Progenitors and Regulates Podocyte Development by Promoting wnt2ba via the Antagonism of hand2
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Citation:
Biomedicines. 2022;10(11):2868. doi:10.3390/biomedicines10112868 Epub:
Not Epub Abstract:
Knowledge about the genetic pathways that control nephron development is essential for better understanding the basis of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Drummond BE, Chambers BE, Wesselman HM, Gibson S, Arceri L, Ulrich MN, Gerlach GF, Kroeger PT, Leshchiner I, Goessling W, Wingert RA. osr1 Maintains Renal Progenitors and Regulates Podocyte Development by Promoting wnt2ba via the Antagonism of hand2. Biomedicines. 2022;10(11):2868. doi:10.3390/biomedicines10112868. |
Antibody-oligonucleotide conjugate achieves central nervous system delivery in animal models for spinal muscular atrophy
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Citation:
JCI Insight. 2022 Nov 8:e154142. doi: 10.1172/jci.insight.154142. Online ahead of print Epub:
Yes Abstract:
Antisense oligonucleotides (ASOs) have emerged as one of the most innovative new genetic drug modalities. However, their high... Delivery Method:
antibody-linked Organism or Cell Type:
mice Citation Extract: Hammond SM, Abendroth F, Goli L, Stoodley J, Burrell M, Thom G, Gurrell I, Ahlskog N, Gait MJ, Wood MJ, Webster CI. Antibody-oligonucleotide conjugate achieves central nervous system delivery in animal models for spinal muscular atrophy. JCI Insight. 2022 Nov 8:e154142. doi: 10.1172/jci.insight.154142. Online ahead of print. |
Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR
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Citation:
Nat Commun. 2022 Nov 5;13(1):6681. doi: 10.1038/s41467-022-34363-w Epub:
Not Epub Abstract:
Transitioning from pluripotency to differentiated cell fates is fundamental to both embryonic development and adult tissue... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK. Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. Nat Commun. 2022 Nov 5;13(1):6681. doi: 10.1038/s41467-022-34363-w. |