You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models

Authors:
Siegerist F, Lange T, Iervolino A, Koppe TM, Zhou W, Capasso G, Endlich K, Endlich N
Citation:
Sci Rep. 2021;11(1):22894. doi:10.1038/s41598-021-00075-2
Epub:
Not Epub
Abstract:
The majority of kidney diseases arise from the loss of podocytes and from morphological changes of their highly complex foot...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Siegerist F, Lange T, Iervolino A, Koppe TM, Zhou W, Capasso G, Endlich K, Endlich N. Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models. Sci Rep. 2021;11(1):22894. doi:10.1038/s41598-021-00075-2.

RGS2 Suppresses Melanoma Growth via Inhibiting MAPK and AKT Signaling Pathways

Authors:
Lin SJ, Huang YC, Chen HY, Fang JY, Hsu SY, Shih HY, Liu YC, Cheng YC
Citation:
Anticancer Res. 2021 Dec;41(12):6135-6145. doi: 10.21873/anticanres.15433
Epub:
Not Epub
Abstract:
Background/Aim: This study aimed to explore RGS2 as a regulator of melanoma cell growth. Materials and Methods: Effect of RGS2...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin SJ, Huang YC, Chen HY, Fang JY, Hsu SY, Shih HY, Liu YC, Cheng YC. RGS2 Suppresses Melanoma Growth via Inhibiting MAPK and AKT Signaling Pathways. Anticancer Res. 2021 Dec;41(12):6135-6145. doi: 10.21873/anticanres.15433.

A Dystrophin Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping

Authors:
Echigoya Y, Trieu N, Duddy W, Moulton HM, Yin H, Partridge TA, Hoffman EP, Kornegay JN, Rohret FA, Rogers CS, Yokota T
Citation:
Int J Mol Sci. 2021;22(23):13065. doi:10.3390/ijms222313065
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a lethal X-linked recessive disorder caused by mutations in the DMD gene and the...
Delivery Method:
peptide-linked, Endo-Porter
Organism or Cell Type:
Sus scrofa domestica (pig)
Citation Extract:
Echigoya Y, Trieu N, Duddy W, Moulton HM, Yin H, Partridge TA, Hoffman EP, Kornegay JN, Rohret FA, Rogers CS, Yokota T. A Dystrophin Exon-52 Deleted Miniature Pig Model of Duchenne Muscular Dystrophy and Evaluation of Exon Skipping. Int J Mol Sci. 2021;22(23):13065. doi:10.3390/ijms222313065 .

Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development

Authors:
Bresciani E, Carrington B, Yu K, Kim EM, Zhen T, Guzman VS, Broadbridge E, Bishop K, Kirby M, Harper U, Wincovitch S, Dell'Orso S, Sartorelli V, Sood R, Liu P
Citation:
Blood Adv. 2021 Dec 14;5(23):4949-4962. doi: 10.1182/bloodadvances.2020003969
Epub:
Not Epub
Abstract:
RUNX1 is essential for the generation of hematopoietic stem cells (HSCs). Runx1-null mouse embryos lack definitive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bresciani E, Carrington B, Yu K, Kim EM, Zhen T, Guzman VS, Broadbridge E, Bishop K, Kirby M, Harper U, Wincovitch S, Dell'Orso S, Sartorelli V, Sood R, Liu P. Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development. Blood Adv. 2021 Dec 14;5(23):4949-4962. doi: 10.1182/bloodadvances.2020003969.

Hapln1b, a central organizer of the ECM, modulates kit signaling to control developmental hematopoiesis in zebrafish

Authors:
Mahony CB, Cacialli P, Pasche C, Monteiro R, Savvides SN, Bertrand JY
Citation:
Blood Adv. 2021 Dec 14;5(23):4935-4948. doi: 10.1182/bloodadvances.2020001524
Epub:
Not Epub
Abstract:
During early vertebrate development, hematopoietic stem and progenitor cells (HSPCs) are produced in hemogenic endothelium...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahony CB, Cacialli P, Pasche C, Monteiro R, Savvides SN, Bertrand JY. Hapln1b, a central organizer of the ECM, modulates kit signaling to control developmental hematopoiesis in zebrafish. Blood Adv. 2021 Dec 14;5(23):4935-4948. doi: 10.1182/bloodadvances.2020001524.

Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration

Authors:
Marsay KS, Greaves S, Mahabaleshwar H, Ho CM, Roehl H, Monk PN, Carney TJ, Partridge LJ
Citation:
PLoS ONE. 2021;16(11):e0260372. doi:10.1371/journal.pone.0260372
Epub:
Not Epub
Abstract:
Collective cell migration is essential for embryonic development and homeostatic processes. During zebrafish development, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marsay KS, Greaves S, Mahabaleshwar H, Ho CM, Roehl H, Monk PN, Carney TJ, Partridge LJ. Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration. PLoS ONE. 2021;16(11):e0260372. doi:10.1371/journal.pone.0260372.

Carbonic anhydrase inhibitor induces otic hair cell apoptosis via an intrinsic pathway and ER stress in zebrafish larvae

Authors:
Matsumoto H, Miyagi H, Nakamura N, Shiga Y, Ohta T, Fujiwara S, Tsuzuki M
Citation:
Toxicol Rep. 2021;[Epub ahead of print] doi:10.1016/j.toxrep.2021.11.018
Epub:
Not Epub
Abstract:
Carbonic anhydrase (CA) catalyzes reversible hydration of CO2 to HCO3− to mediate pH and ion homeostasis. Some chemical...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matsumoto H, Miyagi H, Nakamura N, Shiga Y, Ohta T, Fujiwara S, Tsuzuki M. Carbonic anhydrase inhibitor induces otic hair cell apoptosis via an intrinsic pathway and ER stress in zebrafish larvae. Toxicol Rep. 2021;[Epub ahead of print] doi:10.1016/j.toxrep.2021.11.018.

Vertebrate hemicentin-1 interacts physically and genetically with nidogen-2

Authors:
Zhang J-L, Richetti S, Ramezani T, Welcker D, Lütke S, Pogoda H-M, Hatzold J, Zaucke F, Keene DR, Bloch W, Sengle G, Hammerschmidt M
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.11.24.469833
Epub:
Not Epub
Abstract:
Hemicentins are large proteins of the extracellular matrix that belong to the fibulin family and play pivotal roles during...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang J-L, Richetti S, Ramezani T, Welcker D, Lütke S, Pogoda H-M, Hatzold J, Zaucke F, Keene DR, Bloch W, Sengle G, Hammerschmidt M. Vertebrate hemicentin-1 interacts physically and genetically with nidogen-2. bioRxiv. 2021;[preprint] doi:10.1101/2021.11.24.469833.

Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome

Authors:
Lee S, Shin CH, Lee J, Jeong SD, Hong CR, Kim J-D, Kim A-R, Park B, Son SJ, Kokhan O, Yoo T, Ko JS, Sohn YB, Kim O-H, Ko JM, Cho T-J, Wright NT, Seong JK, Jin S-W, Kang HJ, Kim HH, Choi M.
Citation:
Blood. 2021;138(21):217-28. doi:10.1182/blood.2021010913
Epub:
Not Epub
Abstract:
Shwachman-Diamond syndrome (SDS; OMIM #260400) is caused by variants in SBDS (Shwachman-Bodian-Diamond syndrome gene), which...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee S, Shin CH, Lee J, Jeong SD, Hong CR, Kim J-D, Kim A-R, Park B, Son SJ, Kokhan O, Yoo T, Ko JS, Sohn YB, Kim O-H, Ko JM, Cho T-J, Wright NT, Seong JK, Jin S-W, Kang HJ, Kim HH, Choi M.. Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome. Blood. 2021;138(21):217-28. doi:10.1182/blood.2021010913.

Systematic mapping of rRNA 2’-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis

Authors:
Delhermite J, Tafforeau L, Sharma S, Marchand V, Wacheul L, Lattuca R, Desiderio S, Motorin Y, Bellefroid E, Lafontaine DLJ
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.11.25.469989
Epub:
Not Epub
Abstract:
Ribosomes are essential nanomachines responsible for protein production. Although ribosomes are present in every living cell,...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Delhermite J, Tafforeau L, Sharma S, Marchand V, Wacheul L, Lattuca R, Desiderio S, Motorin Y, Bellefroid E, Lafontaine DLJ. Systematic mapping of rRNA 2’-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis. bioRxiv. 2021;[preprint] doi:10.1101/2021.11.25.469989.

Pages