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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies

Authors:
Zheng S, Gillespie E, Naqvi AS, Hayer KE, Ang Z, Torres-Diz M, Quesnel-Vallieres M, Hottman DA, Bagashev A, Chukinas J, Schmidt C, Asnani M, Shraim R, Taylor DM, Rheingold SR, O'Brien MM, Singh N, Lynch KW, Ruella M, Barash Y, Tasian SK, Thomas-Tikhonenko A
Citation:
Blood Cancer Discov. 2022:3(2):103–15. doi:10.1158/2643-3230.BCD-21-0087
Epub:
Not Epub
Abstract:
Downregulation of surface epitopes causes post-immunotherapy relapses in B-lymphoblastic leukemia (B-ALL). Here we demonstrate...
Link:
https://bloodcancerdiscov.aacrjournals.org/content/early/2021/11/12/2643-3230.BCD-21-0087
Organism or Cell Type:
cell culture
Citation Extract:
Zheng S, Gillespie E, Naqvi AS, Hayer KE, Ang Z, Torres-Diz M, Quesnel-Vallieres M, Hottman DA, Bagashev A, Chukinas J, Schmidt C, Asnani M, Shraim R, Taylor DM, Rheingold SR, O'Brien MM, Singh N, Lynch KW, Ruella M, Barash Y, Tasian SK, Thomas-Tikhonenko A. Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies. Blood Cancer Discov. 2022:3(2):103–15. doi:10.1158/2643-3230.BCD-21-0087.

Distinct Frizzled receptors independently mediate endomesoderm specification and primary archenteron invagination during gastrulation in Nematostella

Authors:
Wijesena N, Sun H, Kumburegama S, Wikramanayake AH
Citation:
Dev Biol. 2021 Nov 9:S0012-1606(21)00234-7. doi: 10.1016/j.ydbio.2021.11.002. Online ahead of print
Epub:
Yes
Abstract:
Endomesodermal cell fate specification and archenteron formation during gastrulation are tightly linked developmental processes...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160621002347
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Wijesena N, Sun H, Kumburegama S, Wikramanayake AH. Distinct Frizzled receptors independently mediate endomesoderm specification and primary archenteron invagination during gastrulation in Nematostella. Dev Biol. 2021 Nov 9:S0012-1606(21)00234-7. doi: 10.1016/j.ydbio.2021.11.002. Online ahead of print.

Nanog regulates primordial germ cell migration through Cxcr4b

Authors:
Sánchez-Sánchez AV, Camp E, Leal-Tassias A, Atkinson SP, Armstrong L, Díaz-Llopis M, Mullor JL
Citation:
Stem Cells. 2010 Sep;28(9):1457-64. doi: 10.1002/stem.469. PMID: 20578184
Epub:
Not Epub
Abstract:
Gonadal development in vertebrates depends on the early determination of primordial germ cells (PGCs) and their correct...
Link:
https://academic.oup.com/stmcls/article-abstract/28/9/1457/6400994
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Sánchez-Sánchez AV, Camp E, Leal-Tassias A, Atkinson SP, Armstrong L, Díaz-Llopis M, Mullor JL. Nanog regulates primordial germ cell migration through Cxcr4b. Stem Cells. 2010 Sep;28(9):1457-64. doi: 10.1002/stem.469. PMID: 20578184.

IFATS collection: Stem cell antigen-1-positive ear mesenchymal stem cells display enhanced adipogenic potential

Authors:
Staszkiewicz J, Gimble JM, Manuel JA, Gawronska-Kozak B
Citation:
Stem Cells. 2008 Oct;26(10):2666-73. doi: 10.1634/stemcells.2008-0270. Epub 2008 Jul 3
Epub:
Not Epub
Abstract:
Hyperplasia is a major contributor to the increase in adipose tissue mass that is characteristic of obesity. However, the...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC2761741/
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse ear mesenchymal stem cells (EMSC)
Citation Extract:
Staszkiewicz J, Gimble JM, Manuel JA, Gawronska-Kozak B. IFATS collection: Stem cell antigen-1-positive ear mesenchymal stem cells display enhanced adipogenic potential. Stem Cells. 2008 Oct;26(10):2666-73. doi: 10.1634/stemcells.2008-0270. Epub 2008 Jul 3.

Shared Segment Analysis and Next-Generation Sequencing Implicates the Retinoic Acid Signaling Pathway in Total Anomalous Pulmonary Venous Return (TAPVR)

Authors:
Nash D, Arrington CB, Kennedy BJ, Yandell M, Wu W, Zhang W, Ware S, Jorde LB, Gruber PJ, Yost HJ, Bowles NE, Bleyl SB
Citation:
PLoS ONE. 2015;10(6):e0131514. doi:10.1371/journal.pone.0131514
Epub:
Not Epub
Abstract:
Most isolated congenital heart defects are thought to be sporadic and are often ascribed to multifactorial mechanisms with...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131514
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nash D, Arrington CB, Kennedy BJ, Yandell M, Wu W, Zhang W, Ware S, Jorde LB, Gruber PJ, Yost HJ, Bowles NE, Bleyl SB. Shared Segment Analysis and Next-Generation Sequencing Implicates the Retinoic Acid Signaling Pathway in Total Anomalous Pulmonary Venous Return (TAPVR). PLoS ONE. 2015;10(6):e0131514. doi:10.1371/journal.pone.0131514.

Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish

Authors:
Anderson EB, Mao Q, Ho RK
Citation:
Dev Biol. 2021 Oct 28:S0012-1606(21)00231-1. doi: 10.1016/j.ydbio.2021.10.008. Online ahead of print
Epub:
Yes
Abstract:
The T-box containing family member, TBX5, has been shown to play important functional roles in the pectoral appendages of a...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160621002311
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson EB, Mao Q, Ho RK. Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish. Dev Biol. 2021 Oct 28:S0012-1606(21)00231-1. doi: 10.1016/j.ydbio.2021.10.008. Online ahead of print.

The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function

Authors:
Koltowska K, Okuda KS, Gloger M, Rondon-Galeano M, Mason E, Xuan J, Dudczig S, Chen H, Arnold H, Skoczylas R, Bower NI, Paterson S, Lagendijk AK, Baillie GJ,Leshchiner I, Simons C, Smith KA, Goessling W, Heath JK, Pearson RB, Sanij E, Schulte-Merker S, Hogan BM
Citation:
Nat Cell Biol. 2021;23(11):1136-47. doi:10.1038/s41556-021-00784-w
Epub:
Not Epub
Abstract:
The development of a functional vasculature requires the coordinated control of cell fate, lineage differentiation and network...
Link:
https://www.nature.com/articles/s41556-021-00784-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Koltowska K, Okuda KS, Gloger M, Rondon-Galeano M, Mason E, Xuan J, Dudczig S, Chen H, Arnold H, Skoczylas R, Bower NI, Paterson S, Lagendijk AK, Baillie GJ,Leshchiner I, Simons C, Smith KA, Goessling W, Heath JK, Pearson RB, Sanij E, Schulte-Merker S, Hogan BM. The RNA helicase Ddx21 controls Vegfc-driven developmental lymphangiogenesis by balancing endothelial cell ribosome biogenesis and p53 function. Nat Cell Biol. 2021;23(11):1136-47. doi:10.1038/s41556-021-00784-w.

MT1 but not MT2 melatonin receptor knockout decreases biliary damage and liver fibrosis during cholestatic liver injury

Authors:
Wu N, Carpino G, Ceci L, Baiocchi L, Francis H, Kennedy L, Zhou T, Chen L, Sato K, Kyritsi K, Meadows V, Ekser B, Franchitto A, Mancinelli R, Onori P, Gaudio E, Glaser S, Alpini G
Citation:
Hepatology. 2021 Nov 7. doi: 10.1002/hep.32233. Online ahead of print
Epub:
Yes
Abstract:
Background & aims: Melatonin reduces biliary damage and liver fibrosis in cholestatic models by interaction with melatonin...
Link:
https://aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep.32233
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Wu N, Carpino G, Ceci L, Baiocchi L, Francis H, Kennedy L, Zhou T, Chen L, Sato K, Kyritsi K, Meadows V, Ekser B, Franchitto A, Mancinelli R, Onori P, Gaudio E, Glaser S, Alpini G. MT1 but not MT2 melatonin receptor knockout decreases biliary damage and liver fibrosis during cholestatic liver injury. Hepatology. 2021 Nov 7. doi: 10.1002/hep.32233. Online ahead of print.

Proper Balance of Small GTPase rab10 Is Critical for PGC Migration in Zebrafish

Authors:
Mo C, Li W, Jia K, Liu W, Yi M
Citation:
Int J Mol Sci. 2021;22(21):11962. doi:10.3390/ijms222111962
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) play important roles in post−transcriptional repression in nearly every biological process including germ...
Link:
https://www.mdpi.com/1422-0067/22/21/11962
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mo C, Li W, Jia K, Liu W, Yi M. Proper Balance of Small GTPase rab10 Is Critical for PGC Migration in Zebrafish. Int J Mol Sci. 2021;22(21):11962. doi:10.3390/ijms222111962.

Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes

Authors:
Swartz SZ, Tan TH, Perillo M, Fakhri N, Wessel GM, Wikramanayake AH, Cheeseman IM
Citation:
Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.10.022
Epub:
Yes
Abstract:
The organismal body axes that are formed during embryogenesis are intimately linked to intrinsic asymmetries established at the...
Link:
https://www.cell.com/current-biology/fulltext/S0960-9822(21)01411-1
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Swartz SZ, Tan TH, Perillo M, Fakhri N, Wessel GM, Wikramanayake AH, Cheeseman IM. Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes. Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.10.022.

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