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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells

Authors:
Lobo S, Pereira C, Oliveira C, Almeida GM
Citation:
Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378
Epub:
Not Epub
Abstract:
De novo expressed CD44 isoforms containing exon-v6 are frequently associated with gastric cancer (GC) aggressiveness, and may...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human gastric cancer, MKN45 & GP202
Citation Extract:
Lobo S, Pereira C, Oliveira C, Almeida GM. Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells. Cancers. 2020;12(9):2072-6694 doi:10.3390/cancers12092378.

Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development

Authors:
Landi E, Karabatas L, Scaglia P, Pisciottano F, Gutierrez M, Ramirez L, Bergadá I, Rey R, Guillermo Jasper H, Mario Domené H, Viviana Plazas P, Domené S
Citation:
Gen Comp Endocrinol. 2020 Aug 20:113591. doi:10.1016/j.ygcen.2020.113591. Online ahead of print
Epub:
Yes
Abstract:
Mammalian acid-labile subunit (ALS) is a serum protein that binds binary complexes between Insulin-like growth factors (IGFs)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Landi E, Karabatas L, Scaglia P, Pisciottano F, Gutierrez M, Ramirez L, Bergadá I, Rey R, Guillermo Jasper H, Mario Domené H, Viviana Plazas P, Domené S. Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development. Gen Comp Endocrinol. 2020 Aug 20:113591. doi:10.1016/j.ygcen.2020.113591. Online ahead of print.

Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons

Authors:
Hahn I, Voelzmann A, Parkin J, Fuelle JB, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.19.257808
Epub:
Not Epub
Abstract:
Axons are the enormously long cable-like cellular processes of neurons that wire nervous systems and have to survive for up to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hahn I, Voelzmann A, Parkin J, Fuelle JB, Slater PG, Lowery LA, Sanchez-Soriano N, Prokop A. Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.19.257808 .

Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein

Authors:
Li D, Adams AM, Johnsen RD, Fletcher S, Wilton SD
Citation:
Molec Ther. 2020 Aug 21;22:263-272. doi:10.1016/j.omtn.2020.08.019
Epub:
Not Epub
Abstract:
Dystrophin plays a crucial role in maintaining sarcolemma stability during muscle contractions, and mutations that prevent the...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: murine H2K mdx myogenic cells, mice
Citation Extract:
Li D, Adams AM, Johnsen RD, Fletcher S, Wilton SD. Morpholino Oligomer-Induced Dystrophin Isoforms to Map the Functional Domains in the Dystrophin Protein. Molec Ther. 2020 Aug 21;22:263-272. doi:10.1016/j.omtn.2020.08.019.

Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development

Authors:
Farley-Barnes KI, Deniz E, Overton MM, Khokha MK, Baserga SJ
Citation:
PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967
Epub:
Not Epub
Abstract:
Dysregulation of ribosome production can lead to a number of developmental disorders called ribosomopathies. Despite the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Farley-Barnes KI, Deniz E, Overton MM, Khokha MK, Baserga SJ. Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development. PLoS Genet. 2020;16(8):e1008967. doi:10.1371/journal.pgen.1008967.

In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence

Authors:
Chou C-H, Wu C-Y, Chen C-L, Zhou J-Q, Kao Y-C, Chen H-Y, Lin P-C
Citation:
Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B
Epub:
Yes
Abstract:
This study monitors dynamic progress of newly developed background-free, target responsive strategy; 2,3-dihydroquinolin-4-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chou C-H, Wu C-Y, Chen C-L, Zhou J-Q, Kao Y-C, Chen H-Y, Lin P-C. In Vivo Monitoring of Carbonic Anhydrases Expression on Growth of Larval Zebrafish: A New Environment-Sensitive Fluorophore for Responsive Turn-On Fluorescence. Chem Comm. 2020;[Epub ahead pf print] doi:10.1039/D0CC03090B.

The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish

Authors:
Zhu J, Wang HT, Chen YR, Yan LY, Han YY, Liu LY, Cao Y, Liu ZZ, Xu HA
Citation:
Neurosci Bull. 2020 Aug 18. doi: 10.1007/s12264-020-00554-y. Online ahead of print.
Epub:
Yes
Abstract:
Joubert syndrome is characterized by unique malformation of the cerebellar vermis. More than thirty Joubert syndrome genes have...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu J, Wang HT, Chen YR, Yan LY, Han YY, Liu LY, Cao Y, Liu ZZ, Xu HA. The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish. Neurosci Bull. 2020 Aug 18. doi: 10.1007/s12264-020-00554-y. Online ahead of print..

Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis

Authors:
Okuda K, Keyser M, Gurevich DB, Sturtzel C, Paterson S, Chen H, Scott M, Condon N, Martin PB, Distel M, Hogan BM
Citation:
bioRxiv 2020;[preprint] doi:10.1101/2020.08.17.254912
Epub:
Not Epub
Abstract:
The formation of new blood vessel networks occurs via angiogenesis during development, tissue repair and disease. Angiogenesis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Okuda K, Keyser M, Gurevich DB, Sturtzel C, Paterson S, Chen H, Scott M, Condon N, Martin PB, Distel M, Hogan BM. Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis. bioRxiv 2020;[preprint] doi:10.1101/2020.08.17.254912.

Production of common carp donor-derived offspring from goldfish surrogate broodstock

Authors:
Franěk R, Kašpar V, Gela D, Pšenička M
Citation:
Research Square. 2020:[preprint] doi:10.21203/rs.3.rs-57467/v1+
Epub:
Not Epub
Abstract:
Background: Common carp is the fourth most-produced species in worldwide aquaculture. Significant efforts are invested in...
Delivery Method:
microinjection
Organism or Cell Type:
Carassius auratus (goldfish)
Citation Extract:
Franěk R, Kašpar V, Gela D, Pšenička M. Production of common carp donor-derived offspring from goldfish surrogate broodstock. Research Square. 2020:[preprint] doi:10.21203/rs.3.rs-57467/v1+.

Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome

Authors:
Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen J-R, Zhang B, Grossfeld P, Mital S, Chitayat D, Wu JC, Rabinovitch M, Nelson TJ, Nie S, Wu SM, Gu M
Citation:
Cell Stem Cell. 2020;[Epub ahead of print] doi:10.1016/j.stem.2020.07.015
Epub:
Not Epub
Abstract:
Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease characterized by abnormalities in the left...
Delivery Method:
injection
Organism or Cell Type:
Xenopus
Citation Extract:
Miao Y, Tian L, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, Moonen J-R, Zhang B, Grossfeld P, Mital S, Chitayat D, Wu JC, Rabinovitch M, Nelson TJ, Nie S, Wu SM, Gu M. Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome. Cell Stem Cell. 2020;[Epub ahead of print] doi:10.1016/j.stem.2020.07.015.

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