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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Calcium-Mediated In Vitro Transfection Technique of Oligonucleotides with Broad Chemical Modification Compatibility
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Citation:
Methods Mol Biol. 2020;2176:141-154. doi: 10.1007/978-1-0716-0771-8_10 Epub:
Not Epub Abstract:
Oligonucleotide drugs (ODs) have gained increasing attention owing to their promising therapeutic potential. One major obstacle... Delivery Method:
calcium enrichment method (CEM) Organism or Cell Type:
cell culture Citation Extract: Wada F, Hori SI, Obika S, Yamamoto T. Calcium-Mediated In Vitro Transfection Technique of Oligonucleotides with Broad Chemical Modification Compatibility. Methods Mol Biol. 2020;2176:141-154. doi: 10.1007/978-1-0716-0771-8_10. |
Inhibition of GABAA-ρ receptors induces retina regeneration in zebrafish
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Citation:
Neural Regen Res. 2021 Feb;16(2):367-374. doi: 10.4103/1673-5374.286972 Epub:
Not Epub Abstract:
A potential treatment for retinal diseases is to induce an endogenous Müller glia (MG)-derived regenerative response to replace... Organism or Cell Type:
zebrafish Citation Extract: Kent MR, Kara N, Patton JG. Inhibition of GABAA-ρ receptors induces retina regeneration in zebrafish. Neural Regen Res. 2021 Feb;16(2):367-374. doi: 10.4103/1673-5374.286972. |
Physiology and morphological correlates of excitatory transmission are preserved in glutamine transporter SN1- depleted mouse frontal cortex
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Citation:
Neurosci. 2020;[Epub] doi:10.1016/j.neuroscience.2020.08.019 Epub:
Not Epub Abstract:
Glutamine is an astroglia-derived precursor of the neurotransmitter glutamate, and its astroglia-to-neuron transfer is... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Popek M, Bobula B, Sowa J, Hess G, Frontczak-Baniewicz M, Albrecht J, Zielińska M. Physiology and morphological correlates of excitatory transmission are preserved in glutamine transporter SN1- depleted mouse frontal cortex. Neurosci. 2020;[Epub] doi:10.1016/j.neuroscience.2020.08.019. |
Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes
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Citation:
Development. 2020 Aug 25;147(16):dev193581. doi: 10.1242/dev.193581 Epub:
Not Epub Abstract:
The Hippo-Yap pathway regulates multiple cellular processes in response to mechanical and other stimuli. In Drosophila, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Flinn MA, Otten C, Brandt ZJ, Bostrom JR, Kenarsary A, Wan TC, Auchampach JA, Abdelilah-Seyfried S, O'Meara CC, Link BA. Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes. Development. 2020 Aug 25;147(16):dev193581. doi: 10.1242/dev.193581. |
Molecular Contribution to Embryonic Aneuploidy and Genotypic Complexity During Initial Cleavage Divisions of Mammalian Development
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.24.220475 Epub:
Not Epub Abstract:
Embryonic aneuploidy is highly complex, often leading to developmental arrest, implantation failure, or spontaneous miscarriage... Delivery Method:
Endo-Porter DMSO, microinjection Organism or Cell Type:
cell culture: Madin-Darby Bovine Kidney (MDBK) epithelial line, Bos Taurus (cattle) embryo Citation Extract: Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Carbone L, Chavez SL. Molecular Contribution to Embryonic Aneuploidy and Genotypic Complexity During Initial Cleavage Divisions of Mammalian Development. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.24.220475 . |
BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis
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Citation:
Sci Rep. 2020:(10)1:14167. doi:10.1038/s41598-020-70806-4 Epub:
Not Epub Abstract:
BVES is a transmembrane protein, our previous work demonstrated that single nucleotide mutations of BVES in tetralogy of fallot... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shi Y, Li Y, Wang Y, Zhu P, Chen Y, Wang H, Yue S, Xia X, Chen J, Jiang Z, Zhou C, Cai W, Yuan H, Wu Y, Wan Y, Li X, Zhu X, Zhou Z, Dai G, Li F, Mo X, Ye X, Fan X, Zhuang J, Wu X, Yuan W. BVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis. Sci Rep. 2020:(10)1:14167. doi:10.1038/s41598-020-70806-4. |
Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.21.260216 Epub:
Not Epub Abstract:
Meiosis is a specialized cell cycle that requires sequential changes to the cell division machinery to facilitate changing... Delivery Method:
microinjection Organism or Cell Type:
Patiria miniata (sea star) Citation Extract: Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN. Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.21.260216 . |
Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.26.010405 Epub:
Not Epub Abstract:
Defects in mitophagy, the selective recycling of mitochondria through autophagy, are linked to aging, sarcopenia, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Goessling W. Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.26.010405. |
The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.259663 Epub:
Not Epub Abstract:
Lymphangiogenesis, the formation of lymphatic vessels is tightly linked to the development of the venous vasculature, both at... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Veloso A, Bleuart A, Orban T, Bruyr J, Cabochette P, Germano RFV, Bernard A, Vanhollebeke B, Martin M, Dequiedt F. The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.259663 . |
Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.
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Citation:
Military Medical Sciences. 2017;41(8):662-666 (Chinese) Epub:
Not Epub Abstract:
Objective: To explore and optimize the processes for synthesis of key intermediates of phosphorodiamidate morpholino... Citation Extract: Chen RX, Guo JY, Song BY, Zhang ND, Xu KL, Wang GB, Dou YY, Wang QH. Exploration and optimization of processes for key intermediates of phosphorodiamidate morpholino oligonucleotides.. Military Medical Sciences. 2017;41(8):662-666 (Chinese). |