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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Splice switching oligonucleotide mediated gene knockdown in B cells and plasma cells.

Authors:
Marchalot A, Lambert J-M, Boyer F, Pollet J, Moreau J, Feuillard J, Faumont N, Delpy L
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.18.302984
Epub:
Not Epub
Abstract:
The need to identify new therapeutic approaches to the treatment of cancers of the B lymphoid lineage is crucial. Unlike CRISPR...
Link:
https://www.biorxiv.org/content/10.1101/2020.09.18.302984v1
Delivery Method:
Vivo-Morpholino versus "transfection" of standard Morpholinos
Organism or Cell Type:
cell culture: SUDHL4 and OCILY10 (DLBCL) lines, primary Human Peripheral Blood Mononuclear B Cells (PBMC)
Citation Extract:
Marchalot A, Lambert J-M, Boyer F, Pollet J, Moreau J, Feuillard J, Faumont N, Delpy L. Splice switching oligonucleotide mediated gene knockdown in B cells and plasma cells.. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.18.302984 .

Molluscan dorsal-ventral patterning relying on BMP2/4 and Chordin provides insights into spiralian development and bilaterian body plan evolution

Authors:
Tan S, Huan P, Liu B
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.11.245670
Epub:
Not Epub
Abstract:
The molecular mechanisms of dorsal-ventral (DV) patterning in Spiralia are poorly understood. The few available studies...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.11.245670v1
Delivery Method:
microinjection
Organism or Cell Type:
Lottia goshimai (limpet)
Citation Extract:
Tan S, Huan P, Liu B. Molluscan dorsal-ventral patterning relying on BMP2/4 and Chordin provides insights into spiralian development and bilaterian body plan evolution. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.11.245670 .

Role of matrix metalloproteinase-9 in neurodevelopmental disorders and experience-dependent plasticity in Xenopus tadpoles

Authors:
Gore S, James EJ, Huang L-C, Park JJ, Berghella A, Thompson A, Cline HT, Aizenman CD
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.123661
Epub:
Not Epub
Abstract:
Matrix metalloproteinase-9 (MMP-9) is a secreted endopeptidase targeting extracellular matrix proteins, creating permissive...
Link:
https://www.biorxiv.org/content/10.1101/2020.05.29.123661v2
Delivery Method:
whole-brain electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gore S, James EJ, Huang L-C, Park JJ, Berghella A, Thompson A, Cline HT, Aizenman CD. Role of matrix metalloproteinase-9 in neurodevelopmental disorders and experience-dependent plasticity in Xenopus tadpoles. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.123661.

Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1

Authors:
Lee M, Betz C, Paatero I, Schellinx N, Yin J, Wilson CW, Ye W, Affolter M, Belting H-G
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.27.269977
Epub:
Not Epub
Abstract:
Organ morphogenesis is driven by a wealth of tightly orchestrated cellular behaviors, which ensure proper organ assembly and...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.27.269977v2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee M, Betz C, Paatero I, Schellinx N, Yin J, Wilson CW, Ye W, Affolter M, Belting H-G. Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.27.269977 .

Planar polarization of cilia in the zebrafish floor-plate involves Par3-mediated posterior localization of highly motile basal bodies

Authors:
Donati A, Schneider-Maunoury S, Vesque C
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/702282
Epub:
Not Epub
Abstract:
To produce a directional flow, ciliated epithelia display a uniform orientation of ciliary beating. Oriented beating requires...
Link:
https://www.biorxiv.org/content/10.1101/702282v2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Donati A, Schneider-Maunoury S, Vesque C. Planar polarization of cilia in the zebrafish floor-plate involves Par3-mediated posterior localization of highly motile basal bodies. bioRxiv. 2020;[preprint] doi:10.1101/702282.

Cell-Cell Adhesion During Nephron Development Is Driven by Wnt/PCP Formin Daam1

Authors:
Krneta-Stankic V, Corkins M, Paulucci-Holthauzen A, Kloc M, Gladden A, Miller R
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.18.256123
Epub:
Not Epub
Abstract:
E-cadherin junctions facilitate the assembly and disassembly of cell-cell contacts that drive development and homeostasis of...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.18.256123v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Krneta-Stankic V, Corkins M, Paulucci-Holthauzen A, Kloc M, Gladden A, Miller R. Cell-Cell Adhesion During Nephron Development Is Driven by Wnt/PCP Formin Daam1. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.18.256123 .

Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk

Authors:
Grimm L, Nakajima H, Chaudhury S, Bower NI, Okuda KS, Cox AG, Harvey NL, Koltowska K, Mochizuki N, Hogan BM
Citation:
Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881
Epub:
Not Epub
Abstract:
Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting...
Link:
https://elifesciences.org/articles/42881
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grimm L, Nakajima H, Chaudhury S, Bower NI, Okuda KS, Cox AG, Harvey NL, Koltowska K, Mochizuki N, Hogan BM. Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk. Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881.

Functional assessment of the “two-hit” model for neurodevelopmental defects in Drosophila and X. laevis

Authors:
Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Inshya Desai, Karthikeyan S, Dagny J. Gould DJ, Yennawar S, Weiner AT, Krishnan A, Rolls M, Lowery LA, Girirajan S
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.14.295923
Epub:
Not Epub
Abstract:
We previously identified a deletion on chromosome 16p12.1 that is mostly inherited and associated with multiple...
Link:
https://www.biorxiv.org/content/10.1101/2020.09.14.295923v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Inshya Desai, Karthikeyan S, Dagny J. Gould DJ, Yennawar S, Weiner AT, Krishnan A, Rolls M, Lowery LA, Girirajan S. Functional assessment of the “two-hit” model for neurodevelopmental defects in Drosophila and X. laevis. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.14.295923 .

TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit

Authors:
Wang Y, Singh AR, Zhao Y, Du T, Huang Y, Wan X, Mukhopadhyay D, Wang Y, Wang N, Zhang P
Citation:
FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print
Epub:
Yes
Abstract:
Sprouting angiogenesis is a highly coordinately process controlled by vascular endothelial growth factor receptor (VEGFR)-Notch...
Link:
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202000186RRR
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang Y, Singh AR, Zhao Y, Du T, Huang Y, Wan X, Mukhopadhyay D, Wang Y, Wang N, Zhang P. TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit. FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print.

Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord

Authors:
Danesin C, Darche-Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, Ohayon D, Glise B, Soula C
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.258707
Epub:
Not Epub
Abstract:
Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates...
Link:
https://www.biorxiv.org/content/10.1101/2020.08.20.258707v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Danesin C, Darche-Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, Ohayon D, Glise B, Soula C. Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.258707.

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