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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis
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Citation:
Biol Open. 2015 Aug 14. pii: bio.010835. doi: 10.1242/bio.010835. [Epub ahead of print] Epub:
Not Epub Abstract:
The paradigm of developmental regulation by Polycomb group (PcG) proteins posits that they maintain silencing outside the... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis Citation Extract: Le Goff E, Martinand-Mari C, Martin M, Feuillard J, Boublik Y, Godefroy N, Mangeat P, Baghdiguian S, Cavalli G. Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis. Biol Open. 2015 Aug 14. pii: bio.010835. doi: 10.1242/bio.010835. [Epub ahead of print]. |
Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum
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Citation:
Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11935-40. doi: 10.1073/pnas.1515864112. Epub 2015 Sep 8. Epub:
Yes Abstract:
Identification and genetic validation of new targets from available genome sequences are critical steps toward the development... Delivery Method:
Vivo-Morpholino & peptide-linked Organism or Cell Type:
Plasmodium falciparum Citation Extract: Garg A, Wesolowski D, Alonso D, Deitsch KW, Ben Mamoun C, Altman S. Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11935-40. doi: 10.1073/pnas.1515864112. Epub 2015 Sep 8.. |
Recoverin depletion accelerates cone photoresponse recovery
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Citation:
Open Biol. 2015 Aug;5(8). pii: 150086. doi: 10.1098/rsob.150086 Epub:
Not Epub Abstract:
The neuronal Ca(2+)-binding protein Recoverin has been shown to regulate phototransduction termination in mammalian rods. Here... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zang J, Keim J, Kastenhuber E, Gesemann M, Neuhauss SC. Recoverin depletion accelerates cone photoresponse recovery. Open Biol. 2015 Aug;5(8). pii: 150086. doi: 10.1098/rsob.150086. |
Conserved overlapping gene arrangement, restricted expression and biochemical activities of DNA polymerase ν; (POLN)
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Citation:
J Biol Chem. 2015 Aug 12. pii: jbc.M115.677419. [Epub ahead of print] Epub:
Yes Abstract:
DNA polymerase ν (POLN) is one of 16 DNA polymerases encoded in vertebrate genomes. It is important to determine its gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Takata KI, Tomida J, Reh S, Swanhart LM, Takata M, Hukriede NA, Wood RD. Conserved overlapping gene arrangement, restricted expression and biochemical activities of DNA polymerase ν; (POLN). J Biol Chem. 2015 Aug 12. pii: jbc.M115.677419. [Epub ahead of print]. |
Directed Alternative Splicing in Nijmegen Breakage Syndrome: Proof of Principle Concerning Its Therapeutical Application
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Citation:
Mol Ther. 2016 Feb;24(1):117-24. doi: 10.1038/mt.2015.144. Epub 2015 Aug 12. Epub:
Yes Abstract:
Over 90% of patients with Nijmegen breakage syndrome (NBS), a hereditary cancer disorder, are homoallelic for a 5bp deletion in... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Salewsky B, Hildebrand G, Rothe S, Parplys AC, Radszewski J, Kieslich M, Wessendorf P, Krenzlin H, Borgmann K, Nussenzweig A, Sperling K, Digweed M. Directed Alternative Splicing in Nijmegen Breakage Syndrome: Proof of Principle Concerning Its Therapeutical Application. Mol Ther. 2016 Feb;24(1):117-24. doi: 10.1038/mt.2015.144. Epub 2015 Aug 12.. |
Identification of genes expressed in the migrating primitive myeloid lineage of Xenopus laevis
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Citation:
Dev Dyn. 2015 Aug 12. doi: 10.1002/dvdy.24314. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: During primitive hematopoiesis in Xenopus, cebpa and spib expressing myeloid cells emerge from the anterior ventral... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Agricola ZN, Jagpal AK, Allbee AW, Prewitt AR, Shifley ET, Rankin SA, Zorn AM, Kenny AP. Identification of genes expressed in the migrating primitive myeloid lineage of Xenopus laevis. Dev Dyn. 2015 Aug 12. doi: 10.1002/dvdy.24314. [Epub ahead of print]. |
Mutations in DCHS1 cause mitral valve prolapse
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Citation:
Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10 Epub:
Not Epub Abstract:
Mitral valve prolapse (MVP) is a common cardiac valve disease that affects nearly 1 in 40 individuals. It can manifest as... Organism or Cell Type:
zebrafish Citation Extract: Durst R, Sauls K, Peal DS, deVlaming A, Toomer K, Leyne M, Salani M, Talkowski ME, Brand H, Perrocheau M, Simpson C, Jett C, Stone MR, Charles F, Chiang C, Lynch SN, Bouatia-Naji N, Delling FN, Freed LA, Tribouilloy C, Le Tourneau T, LeMarec H, Fernandez-Friera L, Solis J, Trujillano D, Ossowski S, Estivill X, Dina C, Bruneval P, Chester A, Schott JJ, Irvine KD, Mao Y, Wessels A, Motiwala T, Puceat M, Tsukasaki Y, Menick DR, Kasiganesan H, Nie X, Broome AM, Williams K, Johnson A, Markwald RR, Jeunemaitre X, Hagege A, Levine RA, Milan DJ, Norris RA, Slaugenhaupt SA. Mutations in DCHS1 cause mitral valve prolapse. Nature. 2015 Sep 3;525(7567):109-13. doi: 10.1038/nature14670. Epub 2015 Aug 10. |
The N-terminal acetyltransferase Naa10 is essential for zebrafish development
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Citation:
Biosci Rep. 2015 Aug 6. pii: BSR20150168. [Epub ahead of print] Epub:
Yes Abstract:
N-terminal acetylation, catalyzed by N-terminal acetyltransferases (NATs), is among the most common protein modifications in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ree RM, Myklebust LM, Thiel P, Foyn H, Fladmark KE, Arnesen T. The N-terminal acetyltransferase Naa10 is essential for zebrafish development. Biosci Rep. 2015 Aug 6. pii: BSR20150168. [Epub ahead of print]. |
Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis
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Citation:
Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4 Epub:
Not Epub Abstract:
Crohn's disease (CD) is associated with delayed neutrophil recruitment and bacterial clearance at sites of acute... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chew TS, O'Shea NR, Sewell GW, Oehlers SH, Mulvey CM, Crosier PS, Godovac-Zimmermann J, Bloom SL, Smith AM, Segal AW. Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis. Dis Model Mech. 2015 Aug 1;8(8):817-29. doi: 10.1242/dmm.020362. Epub 2015 Jun 4. |
Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces
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Citation:
Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012. Epub 2015 Jul 30 Epub:
Not Epub Abstract:
Contact inhibition of locomotion (CIL) is the process through which cells move away from each other after cell-cell contact,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scarpa E, Szabó A, Bibonne A, Theveneau E, Parsons M, Mayor R. Cadherin Switch during EMT in Neural Crest Cells Leads to Contact Inhibition of Locomotion via Repolarization of Forces. Dev Cell. 2015 Aug 24;34(4):421-34. doi: 10.1016/j.devcel.2015.06.012. Epub 2015 Jul 30. |