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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Annexin A3 Regulates Early Blood Vessel Formation

Authors:
Meadows SM, Cleaver O
Citation:
PLoS ONE. 2015;10(7):e0132580. doi:10.1371/journal.pone.0132580
Epub:
Not Epub
Abstract:
Annexins are a large family of calcium binding proteins that associate with cell membrane phospholipids and are involved in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Meadows SM, Cleaver O. Annexin A3 Regulates Early Blood Vessel Formation. PLoS ONE. 2015;10(7):e0132580. doi:10.1371/journal.pone.0132580.

Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor

Authors:
Hor H, Francescatto L, Bartesaghi L, Ortega-Cubero S, Kousi M, Lorenzo-Betancor O, Jiménez-Jiménez FJ, Gironell A, Clarimón J, Drechsel O, Agúndez JAG, Kenzelmann Broz D, Chiquet-Ehrismann R, Lleó A, Coria F, García-Martin E, Alonso-Navarro H, Martí MJ, Kulisevsky J, Hor CN, Ossowski S, Chrast R, Katsanis N, Pastor P, Estivill X
Citation:
Hum Mol Genet. 2015;[Epub ahead of print] doi: 10.1093/hmg/ddv281
Epub:
Yes
Abstract:
Essential tremor (ET) is a common movement disorder with an estimated prevalence of 5% of the population aged over 65 years. In...
Organism or Cell Type:
zebrafish
Citation Extract:
Hor H, Francescatto L, Bartesaghi L, Ortega-Cubero S, Kousi M, Lorenzo-Betancor O, Jiménez-Jiménez FJ, Gironell A, Clarimón J, Drechsel O, Agúndez JAG, Kenzelmann Broz D, Chiquet-Ehrismann R, Lleó A, Coria F, García-Martin E, Alonso-Navarro H, Martí MJ, Kulisevsky J, Hor CN, Ossowski S, Chrast R, Katsanis N, Pastor P, Estivill X. Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor. Hum Mol Genet. 2015;[Epub ahead of print] doi: 10.1093/hmg/ddv281.

Zebrafish TARP Cacng2 is required for the expression and normal development of AMPA receptors at excitatory synapses

Authors:
Roy B, Ahmed KT, Cunningham ME, Ferdous J, Mukherjee R, Zeng W, Chen XZ, Ali DW
Citation:
Dev Neurobiol. 2015 Jul 16. doi: 10.1002/dneu.22327. [Epub ahead of print]
Epub:
Yes
Abstract:
Fast excitatory synaptic transmission in the CNS is mediated by the neurotransmitter glutamate, binding to and activating AMPA...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roy B, Ahmed KT, Cunningham ME, Ferdous J, Mukherjee R, Zeng W, Chen XZ, Ali DW. Zebrafish TARP Cacng2 is required for the expression and normal development of AMPA receptors at excitatory synapses. Dev Neurobiol. 2015 Jul 16. doi: 10.1002/dneu.22327. [Epub ahead of print].

Expression and Misexpression of the miR-183 Family in the Developing Hearing Organ of the Chicken

Authors:
Zhang KD, Stoller ML, Fekete DM
Citation:
PLoS ONE. 2015;10(7):e0132796. doi:10.1371/journal.pone.0132796
Epub:
Not Epub
Abstract:
The miR-183 family consists of 3 related microRNAs (miR-183, miR-96, miR-182) that are required to complete maturation of...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Zhang KD, Stoller ML, Fekete DM. Expression and Misexpression of the miR-183 Family in the Developing Hearing Organ of the Chicken. PLoS ONE. 2015;10(7):e0132796. doi:10.1371/journal.pone.0132796.

Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides

Authors:
Burki U, Keane J, Blain A, O'Donovan L, Gait MJ, Laval SH, Straub V
Citation:
Nucleic Acid Ther. 2015 Jul 15. [Epub ahead of print]
Epub:
Yes
Abstract:
Antisense oligonucleotide (AON)-induced exon skipping is one of the most promising strategies for treating Duchenne muscular...
Delivery Method:
peptide-linked
Citation Extract:
Burki U, Keane J, Blain A, O'Donovan L, Gait MJ, Laval SH, Straub V. Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides. Nucleic Acid Ther. 2015 Jul 15. [Epub ahead of print].

Betaglycan knock-down causes embryonic angiogenesis defects in zebrafish

Authors:
Kamaid A, Molina-Villa T, Mendoza V, Pujades C, Maldonado E, Ispizua Belmonte JC, López-Casillas F
Citation:
Genesis. 2015 Jul 15. doi: 10.1002/dvg.22876. [Epub ahead of print]
Epub:
Yes
Abstract:
Angiogenesis is an essential requirement for embryonic development and adult homeostasis. Its deregulation is a key feature of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kamaid A, Molina-Villa T, Mendoza V, Pujades C, Maldonado E, Ispizua Belmonte JC, López-Casillas F. Betaglycan knock-down causes embryonic angiogenesis defects in zebrafish. Genesis. 2015 Jul 15. doi: 10.1002/dvg.22876. [Epub ahead of print].

Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae

Authors:
Wang H, Semenova S, Kuusela S, Panula P, Lehtonen S
Citation:
FASEB J. 2015 Jul 13. pii: fj.15-271817. [Epub ahead of print]
Epub:
Yes
Abstract:
The central melanocortin system is a key regulator of energy homeostasis. Recent studies indicate that tankyrases (TNKSs),...
Organism or Cell Type:
zebrafish
Citation Extract:
Wang H, Semenova S, Kuusela S, Panula P, Lehtonen S. Tankyrases regulate glucoregulatory mechanisms and somatic growth via the central melanocortin system in zebrafish larvae. FASEB J. 2015 Jul 13. pii: fj.15-271817. [Epub ahead of print].

Mutations within the LINC-HELLP noncoding RNA differentially bind ribosomal and RNA splicing complexes and negatively affect trophoblast differentiation

Authors:
van Dijk M, Visser A, Buabeng KML, Poutsma A, van der Schors RC, Oudejans CBM
Citation:
Hum Mol Genet. 2015;[Epub ahead of print] doi:10.1093/hmg/ddv274
Epub:
Yes
Abstract:
LINC-HELLP, showing chromosomal linkage with the pregnancy-specific HELLP-syndrome in Dutch families, reduces differentiation...
Citation Extract:
van Dijk M, Visser A, Buabeng KML, Poutsma A, van der Schors RC, Oudejans CBM. Mutations within the LINC-HELLP noncoding RNA differentially bind ribosomal and RNA splicing complexes and negatively affect trophoblast differentiation. Hum Mol Genet. 2015;[Epub ahead of print] doi:10.1093/hmg/ddv274.

An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes

Authors:
Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen T-MT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, Horn N, Boldt K, Parry DA, Letteboer SJF, Roosing S, Adams M, Bell SA, Bond J, Higgins J, Morrison EE, Tomlinson DC, Slaats GG, van Dam TJP, Huang L, Kessler K, Giessl A, Logan CV, Boyle EA, Shendure J, Anazi S, Aldahmesh M, Al Hazzaa S, Hegele RA, Ober C, Frosk P, Mhanni AA, Chodirker BN, Chudley AE, Lamont R, Bernier FP, Beaulieu CL, Gordon P, UK10K Consortium, University of Washington Center for Mendelian Genomics, <database limit - authors omitted> Webster AR, Ueffing M, Blacque O, Gleeson JG, Wolfrum U, Beales PL, Gibson T, Doherty D, Mitchison HM, Roepman R, Johnson CA
Citation:
Nat Cell Biol. 2015;[Epub ahead of print] doi:10.1038/ncb3201
Epub:
Yes
Abstract:
Defects in primary cilium biogenesis underlie the ciliopathies, a growing group of genetic disorders. We describe a whole-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen T-MT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, Horn N, Boldt K, Parry DA, Letteboer SJF, Roosing S, Adams M, Bell SA, Bond J, Higgins J, Morrison EE, Tomlinson DC, Slaats GG, van Dam TJP, Huang L, Kessler K, Giessl A, Logan CV, Boyle EA, Shendure J, Anazi S, Aldahmesh M, Al Hazzaa S, Hegele RA, Ober C, Frosk P, Mhanni AA, Chodirker BN, Chudley AE, Lamont R, Bernier FP, Beaulieu CL, Gordon P, UK10K Consortium, University of Washington Center for Mendelian Genomics, <database limit - authors omitted> Webster AR, Ueffing M, Blacque O, Gleeson JG, Wolfrum U, Beales PL, Gibson T, Doherty D, Mitchison HM, Roepman R, Johnson CA. An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nat Cell Biol. 2015;[Epub ahead of print] doi:10.1038/ncb3201.

Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model

Authors:
Chen X, Wang J, Cao Z, Hosaka K, Jensen L, Yang H, Sun Y, Zhuang R, Liu Y, Cao Y
Citation:
Sci Rep. 2015;5:10351. doi:10.1038/srep10351
Epub:
Not Epub
Abstract:
Retinoblastoma is a highly invasive malignant tumor that often invades the brain and metastasizes to distal organs through the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Wang J, Cao Z, Hosaka K, Jensen L, Yang H, Sun Y, Zhuang R, Liu Y, Cao Y. Invasiveness and metastasis of retinoblastoma in an orthotopic zebrafish tumor model. Sci Rep. 2015;5:10351. doi:10.1038/srep10351.

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