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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Proper Activity of Histone H3 Lysine 4 (H3K4) Methyltransferase Is Required for Morphogenesis during Zebrafish Cardiogenesis

Authors:
Kim JD, Kim E, Koun S, Ham HJ, Rhee M, Kim MJ, Huh TL
Citation:
Mol Cells. 2015 May 22. doi: 10.14348/molcells.2015.0053. [Epub ahead of print]
Epub:
Yes
Abstract:
While increasing evidence indicate the important function of histone methylation during development, how this process influence...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JD, Kim E, Koun S, Ham HJ, Rhee M, Kim MJ, Huh TL. Proper Activity of Histone H3 Lysine 4 (H3K4) Methyltransferase Is Required for Morphogenesis during Zebrafish Cardiogenesis. Mol Cells. 2015 May 22. doi: 10.14348/molcells.2015.0053. [Epub ahead of print].

Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation

Authors:
Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, Moley K, Schedl T, Wang Q
Citation:
J Cell Sci. 2015;128:2319-29. doi:10.1242/​jcs.167049
Epub:
Not Epub
Abstract:
Pyruvate dehydrogenase kinases (PDKs) modulate energy homeostasis in multiple tissues/cell types, under various nutrient...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, Moley K, Schedl T, Wang Q. Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation. J Cell Sci. 2015;128:2319-29. doi:10.1242/​jcs.167049.

Nitric Oxide Synthase Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay

Authors:
Ridnour LA, Cheng RY, Weiss JM, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart A, DeGraff WG, Sowers A, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, Trinchieri G, Wiltrout RH, Wink DA
Citation:
Cancer Res. 2015 Jul 15;75(14):2788-99. doi: 10.1158/0008-5472.CAN-14-3011. Epub 2015 May 19.
Epub:
Yes
Abstract:
Nitric oxide synthases (NOS) are important mediators of pro-growth signaling in tumor cells, as they regulate angiogenesis,...
Delivery Method:
injection (mice)
Organism or Cell Type:
cell culture: Raw 267.4, mouse
Citation Extract:
Ridnour LA, Cheng RY, Weiss JM, Soto-Pantoja DR, Basudhar D, Heinecke JL, Stewart A, DeGraff WG, Sowers A, Thetford A, Kesarwala AH, Roberts DD, Young HA, Mitchell JB, Trinchieri G, Wiltrout RH, Wink DA. Nitric Oxide Synthase Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay. Cancer Res. 2015 Jul 15;75(14):2788-99. doi: 10.1158/0008-5472.CAN-14-3011. Epub 2015 May 19..

Xenopus Claudin-6 is required for embryonic pronephros morphogenesis and terminal differentiation

Authors:
Sun J, Wang X, Li C, Mao B
Citation:
Biochem Biophys Res Commun. 2015 May 13. pii: S0006-291X(15)00755-X. doi: 10.1016/j.bbrc.2015.04.065. [Epub ahead of print]
Epub:
Yes
Abstract:
Claudins are tetratransmembrane tight junction proteins and play important roles in regulating paracellular permeability of...
Organism or Cell Type:
Xenopus
Citation Extract:
Sun J, Wang X, Li C, Mao B. Xenopus Claudin-6 is required for embryonic pronephros morphogenesis and terminal differentiation. Biochem Biophys Res Commun. 2015 May 13. pii: S0006-291X(15)00755-X. doi: 10.1016/j.bbrc.2015.04.065. [Epub ahead of print].

The c-Cbl Ubiquitin Ligase Regulates Nuclear β-Catenin and Angiogenesis by Its Tyrosine Phosphorylation Mediated through the Wnt Signaling Pathway

Authors:
Shivanna S, Harrold I, Shashar M, Meyer R, Kiang C, Francis J, Zhao Q, Feng H, Edelman ER, Rahimi N, Chitalia VC
Citation:
J Biol Chem. 2015;290:12537-46. doi:10.1074/jbc.M114.616623
Epub:
Not Epub
Abstract:
Wnt signaling plays important roles in both the tumor-induced angiogenesis and tumorigenesis through the transcriptionally...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shivanna S, Harrold I, Shashar M, Meyer R, Kiang C, Francis J, Zhao Q, Feng H, Edelman ER, Rahimi N, Chitalia VC. The c-Cbl Ubiquitin Ligase Regulates Nuclear β-Catenin and Angiogenesis by Its Tyrosine Phosphorylation Mediated through the Wnt Signaling Pathway. J Biol Chem. 2015;290:12537-46. doi:10.1074/jbc.M114.616623.

Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart, and brain development

Authors:
Van Laarhoven PM, Neitzel LR, Quintana AM, Geiger EA, Zackai EH, Clouthier DE, Artinger KB, Ming JE, Shaikh TH
Citation:
Hum Mol Genet. 2015 May 13. pii: ddv180. [Epub ahead of print]
Epub:
Yes
Abstract:
Kabuki syndrome (KS) is a rare multiple congenital anomaly syndrome characterized by distinctive facial features, global...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Laarhoven PM, Neitzel LR, Quintana AM, Geiger EA, Zackai EH, Clouthier DE, Artinger KB, Ming JE, Shaikh TH. Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart, and brain development. Hum Mol Genet. 2015 May 13. pii: ddv180. [Epub ahead of print].

Two zebrafish hsd3b genes are distinct in function, expression and evolution

Authors:
Lin JC, Hu S, Ho PH, Hsu HJ, Postlethwait J, Chung BC
Citation:
Endocrinology. 2015 May 14:en20141584. [Epub ahead of print]
Epub:
Not Epub
Abstract:
HSD3B catalyzes the synthesis of delta 4 steroids such as progesterone in the adrenals and gonads. Individuals lacking HSD3B2...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin JC, Hu S, Ho PH, Hsu HJ, Postlethwait J, Chung BC. Two zebrafish hsd3b genes are distinct in function, expression and evolution. Endocrinology. 2015 May 14:en20141584. [Epub ahead of print].

Volume changes during active shape fluctuations in cells

Authors:
Taloni A, Kardash E, Salman OU, Truskinovsky L, Zapperi S, La Porta CAM
Citation:
Phys Rev Lett. 2015;[Epub ahead of print]
Epub:
Yes
Abstract:
Cells modify their volume in response to changes in osmotic pressure but it is usually assumed that other active shape...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taloni A, Kardash E, Salman OU, Truskinovsky L, Zapperi S, La Porta CAM. Volume changes during active shape fluctuations in cells. Phys Rev Lett. 2015;[Epub ahead of print].

YAP is essential for tissue tension to ensure vertebrate 3D body shape

Authors:
Porazinski S, Wang H, Asaoka Y, Behrndt M, Miyamoto T, Morita H, Hata S, Sasaki T, Krens SF, Osada Y, Asaka S, Momoi A, Linton S, Miesfeld JB, Link BA, Senga T, Castillo-Morales A, Urrutia AO, Shimizu N, Nagase H, Matsuura S, Bagby S, Kondoh H, Nishina H, Heisenberg CP, Furutani-Seiki M
Citation:
Nature. 2015 Mar 16. doi: 10.1038/nature14215. [Epub ahead of print]
Epub:
Yes
Abstract:
Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Porazinski S, Wang H, Asaoka Y, Behrndt M, Miyamoto T, Morita H, Hata S, Sasaki T, Krens SF, Osada Y, Asaka S, Momoi A, Linton S, Miesfeld JB, Link BA, Senga T, Castillo-Morales A, Urrutia AO, Shimizu N, Nagase H, Matsuura S, Bagby S, Kondoh H, Nishina H, Heisenberg CP, Furutani-Seiki M. YAP is essential for tissue tension to ensure vertebrate 3D body shape. Nature. 2015 Mar 16. doi: 10.1038/nature14215. [Epub ahead of print].

Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis

Authors:
Gago-Rodrigues I, Fernández-Miñán A, Letelier J, Naranjo S, Tena JJ, Gómez-Skarmeta JL, Martinez-Morales JR
Citation:
Nat Commun. 2015 May 12;6:7054. doi: 10.1038/ncomms8054
Epub:
Not Epub
Abstract:
The self-organized morphogenesis of the vertebrate optic cup entails coupling the activation of the retinal gene regulatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gago-Rodrigues I, Fernández-Miñán A, Letelier J, Naranjo S, Tena JJ, Gómez-Skarmeta JL, Martinez-Morales JR. Analysis of opo cis-regulatory landscape uncovers Vsx2 requirement in early eye morphogenesis. Nat Commun. 2015 May 12;6:7054. doi: 10.1038/ncomms8054.

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