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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors
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Citation:
Nat Cell Biol. 2015 Apr 27. doi: 10.1038/ncb3160. [Epub ahead of print] Epub:
Yes Abstract:
The genomic regulatory programmes that underlie human organogenesis are poorly understood. Pancreas development, in particular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cebola I, Rodríguez-Seguí SA, Cho CH, Bessa J, Rovira M, Luengo M, Chhatriwala M, Berry A, Ponsa-Cobas J, Maestro MA, Jennings RE, Pasquali L, Morán I, Castro N, Hanley NA, Gomez-Skarmeta JL, Vallier L, Ferrer J. TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors. Nat Cell Biol. 2015 Apr 27. doi: 10.1038/ncb3160. [Epub ahead of print]. |
Exome sequencing of patients with histiocytoid cardiomyopathy reveals a de novo NDUFB11 mutation that plays a role in the pathogenesis of histiocytoid cardiomyopathy
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Citation:
Am J Med Genet A. 2015 Apr 29. doi: 10.1002/ajmg.a.37138. [Epub ahead of print] Epub:
Yes Abstract:
Histiocytoid cardiomyopathy (Histiocytoid CM) is a rare form of cardiomyopathy observed predominantly in newborn females that... Organism or Cell Type:
zebrafish Citation Extract: Shehata BM, Cundiff CA, Lee K, Sabharwal A, Lalwani MK, Davis AK, Agarwal V, Sivasubbu S, Iannucci GJ, Gibson G. Exome sequencing of patients with histiocytoid cardiomyopathy reveals a de novo NDUFB11 mutation that plays a role in the pathogenesis of histiocytoid cardiomyopathy. Am J Med Genet A. 2015 Apr 29. doi: 10.1002/ajmg.a.37138. [Epub ahead of print]. |
scaRNAs Regulate Splicing and Vertebrate Heart Development
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Citation:
Biochim Biophys Acta. 2015 Apr 23. pii: S0925-4439(15)00122-2. doi: 10.1016/j.bbadis.2015.04.016. [Epub ahead of print] Epub:
Yes Abstract:
Alternative splicing (AS) plays an important role in regulating mammalian heart development, but a link between misregulated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Patil P, Kibiryeva N, Uechi T, Marshall J, O'Brien JE Jr, Artman M, Kenmochi N, Bittel DC. scaRNAs Regulate Splicing and Vertebrate Heart Development. Biochim Biophys Acta. 2015 Apr 23. pii: S0925-4439(15)00122-2. doi: 10.1016/j.bbadis.2015.04.016. [Epub ahead of print]. |
PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development
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Citation:
Dev Biol. 2015 Apr 23. pii: S0012-1606(15)00213-4. doi: 10.1016/j.ydbio.2015.04.013. [Epub ahead of print] Epub:
Not Epub Abstract:
The Zmiz2 (Zimp7) protein and its homolog Zmiz1 (Zimp10) were initially identified in humans as androgen receptor co-activators... Organism or Cell Type:
zebrafish Citation Extract: Moreno-Ayala R, Schnabel D, Salas-Vidal E, Lomelí H. PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development. Dev Biol. 2015 Apr 23. pii: S0012-1606(15)00213-4. doi: 10.1016/j.ydbio.2015.04.013. [Epub ahead of print]. |
Eteplirsen, a Phosphorodiamidate Morpholino Oligomer (PMO) for the Treatment of Duchenne Muscular Dystrophy (DMD): 168 Week Update on Six-Minute Walk Test (6MWT), Pulmonary Function Testing (PFT), and Safety
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Citation:
European Journal of Paediatric Neurology. 2015;V19(Supp 1):S69 Epub:
Not Epub Abstract:
Background/Objective: DMD is a rare, degenerative, X-linked recessive genetic disease that results in progressive muscle loss... Delivery Method:
intravenous infusion Organism or Cell Type:
human Citation Extract: Mendell JR, Rodino-Klapac L, Sahenk Z, Rouch K, Bird L, Lowes L, Alfano L, Berry K, Lewis S, Shontz K, Flanigan K, Shilling C, Duda P, Saoud J. Eteplirsen, a Phosphorodiamidate Morpholino Oligomer (PMO) for the Treatment of Duchenne Muscular Dystrophy (DMD): 168 Week Update on Six-Minute Walk Test (6MWT), Pulmonary Function Testing (PFT), and Safety. European Journal of Paediatric Neurology. 2015;V19(Supp 1):S69. |
Tight junction protein 1a regulates pigment cell organisation during zebrafish colour patterning
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Citation:
eLife. 2015;10.7554/eLife.06545. doi:10.7554/eLife.06545 Epub:
Not Epub Abstract:
Zebrafish display a prominent pattern of alternating dark and light stripes generated by the precise positioning of pigment... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fadeev A, Krauss J, Frohnhöfer HG, Irion U, Nüsslein-Volhard C. Tight junction protein 1a regulates pigment cell organisation during zebrafish colour patterning. eLife. 2015;10.7554/eLife.06545. doi:10.7554/eLife.06545. |
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
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Citation:
J Clin Invest. 2015;[Epub ahead of print] doi:10.1172/JCI75836 Epub:
Yes Abstract:
Glutaminase (GLS), which converts glutamine to glutamate, plays a key role in cancer cell metabolism, growth, and proliferation... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: P493 cells; mouse xenograft p493 tumors Citation Extract: Xiang Y, Stine ZE, Xia J, Lu Y, O’Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, Ooi LL, Lee CGL, Mancuso A, McCallion AS, Le A, Milone MC, Rayport S, Felsher DW, Dang CV. Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. J Clin Invest. 2015;[Epub ahead of print] doi:10.1172/JCI75836. |
Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase
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Citation:
J Cell Biol. 2015;209:275-88. doi:10.1083/jcb.201409001 Epub:
Not Epub Abstract:
Cells polarize to a single front and rear to achieve rapid actin-based motility, but the mechanisms preventing the formation of... Organism or Cell Type:
zebrafish keratocytes Citation Extract: Lou SS, Diz-Muñoz A, Weiner OD, Fletcher DA, Theriot JA. Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase. J Cell Biol. 2015;209:275-88. doi:10.1083/jcb.201409001. |
A Two-Step Pretargeted Nanotherapy for CD20 Crosslinking May Achieve Superior Anti-Lymphoma Efficacy to Rituximab
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Citation:
Theranostics. 2015;5(8):834-46. doi:10.7150/thno.12040 Epub:
Not Epub Abstract:
The use of rituximab, an anti-CD20 mAb, in combination with chemotherapy is the current standard for the treatment of B-cell... Delivery Method:
culture: cell bathing, mouse: injection Organism or Cell Type:
cell culture: patient mantle cell lymphoma Citation Extract: Chu TW, Zhang R, Yang J, Chao MP, Shami PJ, Kopeček J. A Two-Step Pretargeted Nanotherapy for CD20 Crosslinking May Achieve Superior Anti-Lymphoma Efficacy to Rituximab. Theranostics. 2015;5(8):834-46. doi:10.7150/thno.12040. |
Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling
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Citation:
Hum Mol Genet. 2014 Apr 1;23(7):1869-78. doi: 10.1093/hmg/ddt579. Epub 2013 Nov 13 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is caused by a lack of the dystrophin protein and has no effective treatment at present.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kawahara G, Gasperini MJ, Myers JA, Widrick JJ, Eran A, Serafini PR, Alexander MS, Pletcher MT, Morris CA, Kunkel LM. Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling. Hum Mol Genet. 2014 Apr 1;23(7):1869-78. doi: 10.1093/hmg/ddt579. Epub 2013 Nov 13. |