You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Integrating Genetic, Transcriptional, and Functional Analyses to Identify Five Novel Genes for Atrial Fibrillation

Authors:
Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, MacFarlane P, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden A, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR; METASTROKE Consortium; AFGen Consortium, Benjamin EJ, Milan DJ, Melander O, Heckbert S, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT
Citation:
Circulation. 2014 Aug 14. pii: CIRCULATIONAHA.114.009892. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Atrial fibrillation (AF) affects over 30 million individuals worldwide and is associated with an increased risk of...
Link:
http://circ.ahajournals.org/content/130/15/1225.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, MacFarlane P, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden A, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR; METASTROKE Consortium; AFGen Consortium, Benjamin EJ, Milan DJ, Melander O, Heckbert S, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT. Integrating Genetic, Transcriptional, and Functional Analyses to Identify Five Novel Genes for Atrial Fibrillation. Circulation. 2014 Aug 14. pii: CIRCULATIONAHA.114.009892. [Epub ahead of print].

Nkx2.5 is involved in myeloid cell differentiation at anterior ventral blood islands in the Xenopus embryo

Authors:
Sakata H, Maéno M
Citation:
Dev Growth Differ. 2014 Oct 3. doi: 10.1111/dgd.12155. [Epub ahead of print]
Epub:
Yes
Abstract:
We have shown previously that two populations of myeloid cells emerge in the anterior and posterior ventral blood islands (aVBI...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/dgd.12155/abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sakata H, Maéno M. Nkx2.5 is involved in myeloid cell differentiation at anterior ventral blood islands in the Xenopus embryo. Dev Growth Differ. 2014 Oct 3. doi: 10.1111/dgd.12155. [Epub ahead of print].

Evolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation

Authors:
Uy BR, Simoes-Costa M, Koo DE, Sauka-Spengler T, Bronner ME
Citation:
Dev Biol. 2014 Oct 3. pii: S0012-1606(14)00479-5. doi: 10.1016/j.ydbio.2014.09.022. [Epub ahead of print]
Epub:
Yes
Abstract:
Members of the Sox family of transcription factors play a variety of critical developmental roles in both vertebrates and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160614004795
Organism or Cell Type:
Xenopus laevis and Petromyzon marinus
Citation Extract:
Uy BR, Simoes-Costa M, Koo DE, Sauka-Spengler T, Bronner ME. Evolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation. Dev Biol. 2014 Oct 3. pii: S0012-1606(14)00479-5. doi: 10.1016/j.ydbio.2014.09.022. [Epub ahead of print].

The epigenetic factor Kmt2a/Mll1 regulates neural progenitor proliferation and neuronal and glial differentiation

Authors:
Huang Y-C, Shih H-Y, Lin S-J, Chiu C-C, Ma T-L, Yeh T-H, Cheng Y-C
Citation:
Dev Neurobiol. 2014;[Epub ahead of print] doi:10.1002/dneu.22235
Epub:
Yes
Abstract:
Multiple epigenetic factors play a critical role in cell proliferation and differentiation. However, their function in...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dneu.22235/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Huang Y-C, Shih H-Y, Lin S-J, Chiu C-C, Ma T-L, Yeh T-H, Cheng Y-C. The epigenetic factor Kmt2a/Mll1 regulates neural progenitor proliferation and neuronal and glial differentiation. Dev Neurobiol. 2014;[Epub ahead of print] doi:10.1002/dneu.22235.

Mutations in SGOL1 cause a novel cohesinopathy affecting heart and gut rhythm

Authors:
Chetaille P, Preuss C, Burkhard S, Côté JM, Houde C, Castilloux J, Piché J, Gosset N, Leclerc S, Wünnemann F, Thibeault M, Gagnon C, Galli A, Tuck E, Hickson GR, Amine NE, Boufaied I, Lemyre E, de Santa Barbara P, Faure S, Jonzon A, Cameron M, Dietz HC, Gallo-McFarlane E, Benson DW, Moreau C, Labuda D; FORGE Canada Consortium, Zhan SH, Shen Y, Jomphe M, Jones SJ, Bakkers J, Andelfinger G
Citation:
Nat Genet. 2014 Oct 5. doi: 10.1038/ng.3113. [Epub ahead of print]
Epub:
Yes
Abstract:
The pacemaking activity of specialized tissues in the heart and gut results in lifelong rhythmic contractions. Here we describe...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3113.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chetaille P, Preuss C, Burkhard S, Côté JM, Houde C, Castilloux J, Piché J, Gosset N, Leclerc S, Wünnemann F, Thibeault M, Gagnon C, Galli A, Tuck E, Hickson GR, Amine NE, Boufaied I, Lemyre E, de Santa Barbara P, Faure S, Jonzon A, Cameron M, Dietz HC, Gallo-McFarlane E, Benson DW, Moreau C, Labuda D; FORGE Canada Consortium, Zhan SH, Shen Y, Jomphe M, Jones SJ, Bakkers J, Andelfinger G. Mutations in SGOL1 cause a novel cohesinopathy affecting heart and gut rhythm. Nat Genet. 2014 Oct 5. doi: 10.1038/ng.3113. [Epub ahead of print].

ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish

Authors:
Rasighaemi P, Onnebo SM, Liongue C, Ward AC
Citation:
Haematologica. 2015 Jan; 100(1): 23–31.
Epub:
Yes
Abstract:
Chromosomal translocations involving fusions of the human ETV6 (TEL1) gene occur frequently in hematological malignancies....
Link:
http://www.haematologica.org/content/early/2014/09/29/haematol.2014.104091
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rasighaemi P, Onnebo SM, Liongue C, Ward AC. ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish. Haematologica. 2015 Jan; 100(1): 23–31. .

RING finger protein RNF207, a novel regulator of cardiac excitation

Authors:
Roder K, Werdich AA, Li W, Liu M, Kim TY, Organ-Darling LE, Moshal KS, Hwang JM, Lu Y, Choi BR, MacRae CA, Koren G
Citation:
J Biol Chem. 2014 Dec 5;289(49):33730-40. doi: 10.1074/jbc.M114.592295. Epub 2014 Oct 3. PMID: 25281747; PMCID: PMC4256309
Epub:
Yes
Abstract:
Two recent studies [Newton-Cheh et al., Nature Genetics 41, 399-406 (2009); Pfeufer et al., Nature Genetics 41, 407-414 (2009...
Link:
https://www.jbc.org/article/S0021-9258(20)47325-9/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roder K, Werdich AA, Li W, Liu M, Kim TY, Organ-Darling LE, Moshal KS, Hwang JM, Lu Y, Choi BR, MacRae CA, Koren G. RING finger protein RNF207, a novel regulator of cardiac excitation. J Biol Chem. 2014 Dec 5;289(49):33730-40. doi: 10.1074/jbc.M114.592295. Epub 2014 Oct 3. PMID: 25281747; PMCID: PMC4256309.

Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency

Authors:
Ruparelia AA, Oorschot V, Vaz R, Ramm G, Bryson-Richardson RJ
Citation:
Acta Neuropathol. 2014 Oct 2. [Epub ahead of print]
Epub:
Yes
Abstract:
Mutations in the co-chaperone Bcl2-associated athanogene 3 (BAG3) can cause myofibrillar myopathy (MFM), a childhood-onset...
Link:
http://link.springer.com/article/10.1007%2Fs00401-014-1344-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ruparelia AA, Oorschot V, Vaz R, Ramm G, Bryson-Richardson RJ. Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency. Acta Neuropathol. 2014 Oct 2. [Epub ahead of print].

Ethanol-induced upregulation of 10-formyltetrahydrofolate dehydrogenase helps relieve ethanol-induced oxidative stress

Authors:
Hsiao TH, Lin CJ, Chung YS, Lee GH, Kao TT, Chang WN, Chen BH, Hung JJ, Fu TF
Citation:
Mol Cell Biol. 2014 Feb;34(3):498-509. doi: 10.1128/MCB.01427-13. Epub 2013 Nov 25
Epub:
Not Epub
Abstract:
Alcoholism induces folate deficiency and increases the risk for embryonic anomalies. However, the interplay between ethanol...
Link:
http://mcb.asm.org/content/34/3/498.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsiao TH, Lin CJ, Chung YS, Lee GH, Kao TT, Chang WN, Chen BH, Hung JJ, Fu TF. Ethanol-induced upregulation of 10-formyltetrahydrofolate dehydrogenase helps relieve ethanol-induced oxidative stress. Mol Cell Biol. 2014 Feb;34(3):498-509. doi: 10.1128/MCB.01427-13. Epub 2013 Nov 25.

Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases

Authors:
Wiley DJ, Juan I, Le H, Cai X, Baumbach L, Beattie C, D'Urso G
Citation:
F1000Res. 2014 Jun 2;3:121. doi: 10.12688/f1000research.4188.1. eCollection 2014
Epub:
Not Epub
Abstract:
Genetic interaction networks that underlie most human diseases are highly complex and poorly defined. Better-defined networks...
Link:
http://f1000research.com/articles/3-121/v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiley DJ, Juan I, Le H, Cai X, Baumbach L, Beattie C, D'Urso G. Yeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseases. F1000Res. 2014 Jun 2;3:121. doi: 10.12688/f1000research.4188.1. eCollection 2014.

Pages