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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Cell-fibronectin interactions propel vertebrate trunk elongation via tissue mechanics

Authors:
Dray N, Lawton A, Nandi A, Jülich D, Emonet T, Holley SA
Citation:
Curr Biol. 2013 Jul 22;23(14):1335-41. doi: 10.1016/j.cub.2013.05.052. Epub 2013 Jun 27
Epub:
Not Epub
Abstract:
During embryonic development and tissue homeostasis, cells produce and remodel the extracellular matrix (ECM). The ECM...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725194/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dray N, Lawton A, Nandi A, Jülich D, Emonet T, Holley SA. Cell-fibronectin interactions propel vertebrate trunk elongation via tissue mechanics. Curr Biol. 2013 Jul 22;23(14):1335-41. doi: 10.1016/j.cub.2013.05.052. Epub 2013 Jun 27.

IRE1α knockdown rescues tunicamycin-induced developmental defects and apoptosis in Xenopus laevis

Authors:
Yuan L, Yu J, Li X, Feng J, Yin C, Wang X
Citation:
J Biomed Res. 2014 Jul;28(4):275-81. doi: 10.7555/JBR.28.20120075. Epub 2014 Mar 15
Epub:
Not Epub
Abstract:
Inositol requiring enzyme-1 (IRE1) is highly conserved from yeasts to humans. Upon endoplasmic reticulum (ER) stress, IRE1...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102841/
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yuan L, Yu J, Li X, Feng J, Yin C, Wang X. IRE1α knockdown rescues tunicamycin-induced developmental defects and apoptosis in Xenopus laevis. J Biomed Res. 2014 Jul;28(4):275-81. doi: 10.7555/JBR.28.20120075. Epub 2014 Mar 15.

Modular Evolution of DNA-Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks

Authors:
Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF
Citation:
Mol Biol Evol. 2014 Oct;31(10):2672-88. doi: 10.1093/molbev/msu213. Epub 2014 Jul 12
Epub:
Not Epub
Abstract:
Gene regulatory networks (GRNs) describe the progression of transcriptional states that take a single-celled zygote to a...
Link:
http://mbe.oxfordjournals.org/content/31/10/2672.long
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF. Modular Evolution of DNA-Binding Preference of a Tbrain Transcription Factor Provides a Mechanism for Modifying Gene Regulatory Networks. Mol Biol Evol. 2014 Oct;31(10):2672-88. doi: 10.1093/molbev/msu213. Epub 2014 Jul 12.

Cholestenoic acids regulate motor neuron survival via liver X receptors

Authors:
Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, Honda A, Mizuochi T, Kimura A, Nittono H, De Michele G, Carbone R, Criscuolo C, Yau JL, Seckl JR, Schüle R, Schöls L, Sailer AW, Kuhle J, Fraidakis MJ, Gustafsson JA, Steffensen KR, Björkhem I, Ernfors P, Sjövall J, Arenas E, Wang Y
Citation:
J Clin Invest. 2014 Oct 1. pii: 68506. doi: 10.1172/JCI68506. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cholestenoic acids are formed as intermediates in metabolism of cholesterol to bile acids, and the biosynthetic enzymes that...
Link:
http://www.jci.org/articles/view/68506
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Theofilopoulos S, Griffiths WJ, Crick PJ, Yang S, Meljon A, Ogundare M, Kitambi SS, Lockhart A, Tuschl K, Clayton PT, Morris AA, Martinez A, Reddy MA, Martinuzzi A, Bassi MT, Honda A, Mizuochi T, Kimura A, Nittono H, De Michele G, Carbone R, Criscuolo C, Yau JL, Seckl JR, Schüle R, Schöls L, Sailer AW, Kuhle J, Fraidakis MJ, Gustafsson JA, Steffensen KR, Björkhem I, Ernfors P, Sjövall J, Arenas E, Wang Y. Cholestenoic acids regulate motor neuron survival via liver X receptors. J Clin Invest. 2014 Oct 1. pii: 68506. doi: 10.1172/JCI68506. [Epub ahead of print].

Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression

Authors:
Zhao X, Jiang B, Hu H, Mao F, Mi J, Li Z, Liu Q, Shao C, Gong Y
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu503
Epub:
Not Epub
Abstract:
CUL4A and CUL4B are closely related cullin family members and can each assemble a Cullin-RING E3 ligase complex (CRL) and...
Link:
http://hmg.oxfordjournals.org/content/early/2014/09/30/hmg.ddu503.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao X, Jiang B, Hu H, Mao F, Mi J, Li Z, Liu Q, Shao C, Gong Y. Zebrafish cul4a, but not cul4b, modulates cardiac and forelimb development by upregulating tbx5a expression. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu503.

Contact-Mediated Inhibition Between Oligodendrocyte Progenitor Cells and Motor Exit Point Glia Establishes the Spinal Cord Transition Zone

Authors:
Smith CJ, Morris AD, Welsh TG, Kucenas S
Citation:
PLoS Biol. 2014;12(9):e1001961. doi:10.1371/journal.pbio.1001961
Epub:
Not Epub
Abstract:
Rapid conduction of action potentials along motor axons requires that oligodendrocytes and Schwann cells myelinate distinct...
Link:
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001961
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Smith CJ, Morris AD, Welsh TG, Kucenas S. Contact-Mediated Inhibition Between Oligodendrocyte Progenitor Cells and Motor Exit Point Glia Establishes the Spinal Cord Transition Zone. PLoS Biol. 2014;12(9):e1001961. doi:10.1371/journal.pbio.1001961.

Stage-dependent plasticity of the anterior neural folds to form neural crest

Authors:
Ezin M, Barembaum M, Bronner ME
Citation:
Differentiation. 2014 Sep 25. pii: S0301-4681(14)00053-X. doi: 10.1016/j.diff.2014.09.003. [Epub ahead of print]
Epub:
Yes
Abstract:
The anterior neural fold (ANF) is the only region of the neural tube that does not produce neural crest cells. Instead, ANF...
Link:
http://www.sciencedirect.com/science/article/pii/S030146811400053X
Organism or Cell Type:
chick
Citation Extract:
Ezin M, Barembaum M, Bronner ME. Stage-dependent plasticity of the anterior neural folds to form neural crest. Differentiation. 2014 Sep 25. pii: S0301-4681(14)00053-X. doi: 10.1016/j.diff.2014.09.003. [Epub ahead of print].

Leptin and IL-6 Family Cytokines Synergize to Stimulate Müller Glia Reprogramming and Retina Regeneration

Authors:
Zhao X-F, Wan J, Powell C, Ramachandran R, Myers Jr MG, Goldman D
Citation:
Cell Rep. 2014 Oct 9;9(1):272-84. doi: 10.1016/j.celrep.2014.08.047. Epub 2014 Sep 25.
Epub:
Not Epub
Abstract:
Unlike mammals, zebrafish can regenerate a damaged retina. This remarkable regenerative response is mediated by Müller glia (MG...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194149/
Delivery Method:
retinal injury & electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao X-F, Wan J, Powell C, Ramachandran R, Myers Jr MG, Goldman D. Leptin and IL-6 Family Cytokines Synergize to Stimulate Müller Glia Reprogramming and Retina Regeneration. Cell Rep. 2014 Oct 9;9(1):272-84. doi: 10.1016/j.celrep.2014.08.047. Epub 2014 Sep 25..

Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development

Authors:
Muto A, Ikeda S, Lopez-Burks ME, Kikuchi Y, Calof AL, Lander AD, Schilling TF
Citation:
PLoS Genet. 2014;10(9):e1004671. doi:10.1371/journal.pgen.1004671
Epub:
Not Epub
Abstract:
Haploinsufficiency for Nipbl, a cohesin loading protein, causes Cornelia de Lange Syndrome (CdLS), the most common “...
Link:
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004671
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Muto A, Ikeda S, Lopez-Burks ME, Kikuchi Y, Calof AL, Lander AD, Schilling TF. Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development. PLoS Genet. 2014;10(9):e1004671. doi:10.1371/journal.pgen.1004671.

Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features

Authors:
Lessel D, Vaz B, Halder S, Lockhart PJ, Marinovic-Terzic I, Lopez-Mosqueda J, Philipp M, Sim JCH, Smith KR, Oehler J, Cabrera E, Freire R, Pope K, Nahid A, Norris F, Leventer RJ, Delatycki MB, Barbi G, von Ameln S, Högel J, Degoricija M, Fertig R, Burkhalter MD, Hofmann K, Thiele H, Altmüller J, Nürnberg G, Nürnberg P, Bahlo M, Martin GM, Aalfs CM, Oshima J, Terzic J, Amor DJ, Dikic I, Ramadan K, Kubisch C
Citation:
Nat Genet. 2014;[Epub ahead of print] doi:10.1038/ng.3103
Epub:
Yes
Abstract:
Age-related degenerative and malignant diseases represent major challenges for health care systems. Elucidation of the...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3103.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lessel D, Vaz B, Halder S, Lockhart PJ, Marinovic-Terzic I, Lopez-Mosqueda J, Philipp M, Sim JCH, Smith KR, Oehler J, Cabrera E, Freire R, Pope K, Nahid A, Norris F, Leventer RJ, Delatycki MB, Barbi G, von Ameln S, Högel J, Degoricija M, Fertig R, Burkhalter MD, Hofmann K, Thiele H, Altmüller J, Nürnberg G, Nürnberg P, Bahlo M, Martin GM, Aalfs CM, Oshima J, Terzic J, Amor DJ, Dikic I, Ramadan K, Kubisch C. Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features. Nat Genet. 2014;[Epub ahead of print] doi:10.1038/ng.3103.

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