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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes

Authors:
Dong X, Li J, He L, Gu C, Jia W, Yue Y, Li J, Zhang Q, Chu L, Zhao Q
Citation:
J Biol Chem. 2017 Aug 4;292(31):13045-13055. doi: 10.1074/jbc.M117.777094. Epub 2017 Jun 16
Epub:
Not Epub
Abstract:
Transcription factors play crucial roles in patterning posterior neuroectoderm. Previously, zinc finger transcription factor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dong X, Li J, He L, Gu C, Jia W, Yue Y, Li J, Zhang Q, Chu L, Zhao Q. Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes. J Biol Chem. 2017 Aug 4;292(31):13045-13055. doi: 10.1074/jbc.M117.777094. Epub 2017 Jun 16.

hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus

Authors:
Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K
Citation:
Dev Biol. 2017 Aug 1. pii: S0012-1606(17)30032-5. doi: 10.1016/j.ydbio.2017.07.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Development of the central nervous system requires orchestration of morphogenetic processes which drive elevation and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K. hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus. Dev Biol. 2017 Aug 1. pii: S0012-1606(17)30032-5. doi: 10.1016/j.ydbio.2017.07.020. [Epub ahead of print].

Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality

Authors:
Kim JG, Bae SJ, Lee HS, Park JH, Kim KW
Citation:
PLoS One. 2017 Aug 3;12(8):e0182047. doi: 10.1371/journal.pone.0182047. eCollection 2017
Epub:
Not Epub
Abstract:
Left-right asymmetric organ development is critical to establish a proper body plan of vertebrates. In zebrafish, the Kupffer...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JG, Bae SJ, Lee HS, Park JH, Kim KW. Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality. PLoS One. 2017 Aug 3;12(8):e0182047. doi: 10.1371/journal.pone.0182047. eCollection 2017.

In Vitro Modulation of Endogenous Alternative Splicing Using Splice-Switching Antisense Oligonucleotides

Authors:
Park JE, Cartegni L
Citation:
Methods Mol Biol. 2017;1648:39-52. doi: 10.1007/978-1-4939-7204-3_4
Epub:
Not Epub
Abstract:
Regulation of alternative splicing can be harnessed by antisense-based compounds to control gene expression. Antisense-mediated...
Organism or Cell Type:
cell culture
Citation Extract:
Park JE, Cartegni L. In Vitro Modulation of Endogenous Alternative Splicing Using Splice-Switching Antisense Oligonucleotides. Methods Mol Biol. 2017;1648:39-52. doi: 10.1007/978-1-4939-7204-3_4.

N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis

Authors:
Lewis PA, Bradley IC, Pizzey AR, Isaacs HV, Evans GJO
Citation:
J Neurosci. 2017;[Published online] doi:10.1523/JNEUROSCI.3881-16.2017
Epub:
Not Epub
Abstract:
The presence of the neuronal-specific N1-Src splice variant of the C-Src tyrosine kinase is conserved through vertebrate...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Lewis PA, Bradley IC, Pizzey AR, Isaacs HV, Evans GJO. N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis. J Neurosci. 2017;[Published online] doi:10.1523/JNEUROSCI.3881-16.2017.

Metformin Inhibits Cyst Formation in a Zebrafish Model of Polycystin-2 Deficiency

Authors:
Chang M-Y, Ma T-L, Hung C-C, Tian Y-C, Chen Y-C, Yang C-W, Cheng Y-C
Citation:
Sci Rep. 2017;7:7161. doi:10.1038/s41598-017-07300-x
Epub:
Not Epub
Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is a common kidney disease caused by mutations in PKD1 or PKD2. Metformin...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chang M-Y, Ma T-L, Hung C-C, Tian Y-C, Chen Y-C, Yang C-W, Cheng Y-C. Metformin Inhibits Cyst Formation in a Zebrafish Model of Polycystin-2 Deficiency. Sci Rep. 2017;7:7161. doi:10.1038/s41598-017-07300-x.

Flow-Responsive VEGFR-PKCɛ Signaling Mediates Glycolytic Metabolites for Vascular Repair

Authors:
Baek KI, Li R, Jen N, Choi H, Kaboodrangi A, Ping P, Liem D, Beebe T, Hsiai TK
Citation:
Antioxid Redox Signal. 2017 Aug 1. doi: 10.1089/ars.2017.7044. [Epub ahead of print]
Epub:
Yes
Abstract:
Aims - Hemodynamic shear stress participates in maintaining vascular redox status. Elucidating flow-mediated endothelial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baek KI, Li R, Jen N, Choi H, Kaboodrangi A, Ping P, Liem D, Beebe T, Hsiai TK. Flow-Responsive VEGFR-PKCɛ Signaling Mediates Glycolytic Metabolites for Vascular Repair. Antioxid Redox Signal. 2017 Aug 1. doi: 10.1089/ars.2017.7044. [Epub ahead of print].

Nanog suppresses the expression of vasa by directly regulating nlk1 in the early zebrafish embryo

Authors:
Liu Y, Xue W, Zhu L, Ye D, Zhu X, Wang H, Sun Y, Deng F
Citation:
Biochimie. 2017 Jul 28. pii: S0300-9084(17)30185-2. doi: 10.1016/j.biochi.2017.07.014. [Epub ahead of print]
Epub:
Yes
Abstract:
Nanog is a homeodomain transcription factor that is essential for maintenance of pluripotency and self-renewal of embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Y, Xue W, Zhu L, Ye D, Zhu X, Wang H, Sun Y, Deng F. Nanog suppresses the expression of vasa by directly regulating nlk1 in the early zebrafish embryo. Biochimie. 2017 Jul 28. pii: S0300-9084(17)30185-2. doi: 10.1016/j.biochi.2017.07.014. [Epub ahead of print].

Tensile forces govern germ-layer organization in zebrafish

Authors:
Krieg M, Arboleda-Estudillo Y, Puech PH, Käfer J, Graner F, Müller DJ, Heisenberg CP
Citation:
Nat Cell Biol. 2008 Apr;10(4):429-36. doi: 10.1038/ncb1705. Epub 2008 Mar 23
Epub:
Not Epub
Abstract:
Understanding the factors that direct tissue organization during development is one of the most fundamental goals in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Krieg M, Arboleda-Estudillo Y, Puech PH, Käfer J, Graner F, Müller DJ, Heisenberg CP. Tensile forces govern germ-layer organization in zebrafish. Nat Cell Biol. 2008 Apr;10(4):429-36. doi: 10.1038/ncb1705. Epub 2008 Mar 23.

Sorting at embryonic boundaries requires high heterotypic interfacial tension

Authors:
Canty L, Zarour E, Kashkooli L, François P, Fagotto F
Citation:
Nat Comm. 2017;8:157 doi:10.1038/s41467-017-00146-x
Epub:
Not Epub
Abstract:
The establishment of sharp boundaries is essential for segregation of embryonic tissues during development, but the underlying...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Canty L, Zarour E, Kashkooli L, François P, Fagotto F. Sorting at embryonic boundaries requires high heterotypic interfacial tension. Nat Comm. 2017;8:157 doi:10.1038/s41467-017-00146-x.

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