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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Pituitary adenylate cyclase-activating polypeptide (PACAP) in zebrafish models of nephrotic syndrome
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Citation:
PLoS ONE. 2017;12(7):e0182100. doi:journal.pone.0182100 Epub:
Not Epub Abstract:
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an inhibitor of megakaryopoiesis and platelet function. Recently... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Eneman B, Elmonem MA, van den Heuvel LP, Khodaparast L, Khodaparast L, van Geet C, Freson K, Levtchenko E. Pituitary adenylate cyclase-activating polypeptide (PACAP) in zebrafish models of nephrotic syndrome. PLoS ONE. 2017;12(7):e0182100. doi:journal.pone.0182100. |
Quantitative antisense screening and optimization for exon 51 skipping in Duchenne muscular dystrophy
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Citation:
Molec Ther. 2017:[Accepted manucsript] doi:10.1016/j.ymthe.2017.07.014 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD), the most common lethal genetic disorder, is caused by mutations in the dystrophin (DMD) gene... Organism or Cell Type:
cell culture: immortalized DMD muscle cells, humanized DMD mice Citation Extract: Echigoya Y, Rowel Q. Lim KRQ, Trieu N, Bao B, Miskew B, Vila MC, Novak JS, Hara Y, Lee J, Touznik A, Mamchaoui K, Aoki Y, Takeda S, Nagaraju K, Mouly V, Maruyama R, Duddy W, Yokota T. Quantitative antisense screening and optimization for exon 51 skipping in Duchenne muscular dystrophy. Molec Ther. 2017:[Accepted manucsript] doi:10.1016/j.ymthe.2017.07.014. |
Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors
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Citation:
Cancer Gene Ther. 2017:[Advance publication] doi:10.1038/cgt.2017.27 Epub:
Not Epub Abstract:
The DNA repair enzyme O6-methylguanine DNA methyltransferase (MGMT) is epigenetically silenced in some tumors by MGMT gene... Delivery Method:
scrape, DharmaFECT, ionizing radiation Organism or Cell Type:
cell culture: T98G glioma, H460 and A549 non-small cell lung carcinoma, xenograft mice Citation Extract: Ambady P, Wu YJ, Walker JM, Kersch C, Pagel MA, Woltjer RL, Fu R, Muldoon LL, Neuwelt EA. Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors. Cancer Gene Ther. 2017:[Advance publication] doi:10.1038/cgt.2017.27. |
Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis
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Citation:
PLoS Pathog. 2-17;13(7):e1006526. doi:10.1371/journal.ppat.1006526 Epub:
Not Epub Abstract:
Enterococcus faecalis is an opportunistic pathogen frequently isolated in clinical settings. This organism is intrinsically... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Salamaga B, Prajsnar TK, Jareño-Martinez A, Willemse J, Bewley MA, Chau F, Ben Belkacem T, Meijer AH, Dockrell DH, Renshaw SA, Mesnage S. Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis. PLoS Pathog. 2-17;13(7):e1006526. doi:10.1371/journal.ppat.1006526. |
Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish
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Citation:
Nat Comm. 2017;8:126. doi:10.1038/s41467-017-00143-0 Epub:
Not Epub Abstract:
The inhibitory extracellular matrix in a spinal lesion site is a major impediment to axonal regeneration in mammals. In... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Wehner D, Tsarouchas TM, Michael A, Haase C, Weidinger G, Reimer MM, Becker T, Becker CG. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish. Nat Comm. 2017;8:126. doi:10.1038/s41467-017-00143-0. |
An Actomyosin-Arf-GEF Negative Feedback Loop for Tissue Elongation under Stress
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Citation:
Curr Biol. 2017;{Epub ahead of print] doi:10.1016/j.cub.2017.06.038 Epub:
Yes Abstract:
In response to a pulling force, a material can elongate, hold fast, or fracture. During animal development, multi-cellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: West JJ, Zulueta-Coarasa T, Maier JA, Lee DM, Bruce AEE, Fernandez-Gonzalez R, Harris TJC. An Actomyosin-Arf-GEF Negative Feedback Loop for Tissue Elongation under Stress. Curr Biol. 2017;{Epub ahead of print] doi:10.1016/j.cub.2017.06.038. |
Protein kinase Cϵ stabilizes β-catenin and regulates its subcellular localization in podocytes
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Citation:
J Biol Chem. 2017;292:12100-10 doi:10.1074/jbc.M117.775700 Epub:
Not Epub Abstract:
Kidney disease has been linked to dysregulated signaling via PKC in kidney cells such as podocytes. PKCα is a conventional... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Duong M, Yu X, Teng B, Schroder P, Haller H, Eschenburg S, Schiffer M. Protein kinase Cϵ stabilizes β-catenin and regulates its subcellular localization in podocytes. J Biol Chem. 2017;292:12100-10 doi:10.1074/jbc.M117.775700. |
Number of inadvertent RNA targets for morpholino knockdown in Danio rerio is largely underestimated: evidence from the study of Ser/Arg-rich splicing factors
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Citation:
Nucleic Acids Res. 2017;[Epub ahead of print] doi:10.1093/nar/gkx638 Epub:
Yes Abstract:
Although the involvement of Ser/Arg-rich (SR) proteins in RNA metabolism is well documented, their role in vertebrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Joris M, Schloesser M, Baurain D, Hanikenne M, Muller M, Motte P. Number of inadvertent RNA targets for morpholino knockdown in Danio rerio is largely underestimated: evidence from the study of Ser/Arg-rich splicing factors. Nucleic Acids Res. 2017;[Epub ahead of print] doi:10.1093/nar/gkx638. |
SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development
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Citation:
Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15. Epub:
Not Epub Abstract:
Arterial specification and differentiation are influenced by a number of regulatory pathways. While it is known that the Vegfa-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M. SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15.. |
Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues
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Citation:
J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.203471 Epub:
Yes Abstract:
Macrophages infiltrate and establish in developing organs from an early stage, often before these have become vascularised.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Demy DL, Tauzin M, Lancino M, le Cabec V, Redd M, Murayama E, Maridonneau-Parini I, Trede N, Herbomel P. Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues. J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.203471. |