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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12171 scientific papers returned from the database with the search filters currently being used below.

Zebrafish macroH2A variants have distinct embryo localization and function

Authors:
Gonzalez-Munoz E, Arboleda-Estudillo Y, Chanumolu SK, Otu HH, Cibelli JB
Citation:
Sci Rep. 2019 Jun 14;9(1):8632. doi: 10.1038/s41598-019-45058-6
Epub:
Not Epub
Abstract:
Mouse and cell-based studies have shown that macroH2A histone variants predominantly associate with heterochromatin. Functional...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gonzalez-Munoz E, Arboleda-Estudillo Y, Chanumolu SK, Otu HH, Cibelli JB. Zebrafish macroH2A variants have distinct embryo localization and function. Sci Rep. 2019 Jun 14;9(1):8632. doi: 10.1038/s41598-019-45058-6.

β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor

Authors:
Weil P, van den Bruck R, Ziegenhals T, Juranek S, Goedde D, Orth V, Wirth S, Jenke AC, Postberg J
Citation:
Gut. 2019;[Epub ahead of print] doi:10.1136/gutjnl-2019-319015
Epub:
Yes
Abstract:
[no abstract available]
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weil P, van den Bruck R, Ziegenhals T, Juranek S, Goedde D, Orth V, Wirth S, Jenke AC, Postberg J. β6 integrinosis: a new lethal autosomal recessive ITGB6 disorder leading to impaired conformational transitions of the αVβ6 integrin receptor. Gut. 2019;[Epub ahead of print] doi:10.1136/gutjnl-2019-319015 .

The Spatiotemporal Control of Zygotic Genome Activation

Authors:
Gentsch GE, Owens NDL, Smith JC
Citation:
iScience. 2019 Jun 11;16:485-498. doi: 10.1016/j.isci.2019.06.013. [Epub ahead of print]
Epub:
Not Epub
Abstract:
One of the earliest and most significant events in embryonic development is zygotic genome activation (ZGA). In several species...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Gentsch GE, Owens NDL, Smith JC. The Spatiotemporal Control of Zygotic Genome Activation. iScience. 2019 Jun 11;16:485-498. doi: 10.1016/j.isci.2019.06.013. [Epub ahead of print].

The nuclear pore proteins Nup88/214 and T-ALL-associated NUP214 fusion proteins regulate Notch signaling

Authors:
Kindermann B, Valkova C, Krämer A, Perner B, Engelmann C, Behrendt L, Kritsch D, Jungnickel B, Kehlenbach RH, Oswald F, Englert C, Kaether C
Citation:
J Biol Chem. 2019 Jun 11. pii: jbc.RA118.006357. doi: 10.1074/jbc.RA118.006357. [Epub ahead of print]
Epub:
Yes
Abstract:
The Notch receptor is a key mediator of developmental programs and cell-fate decisions. Imbalanced Notch signaling leads to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kindermann B, Valkova C, Krämer A, Perner B, Engelmann C, Behrendt L, Kritsch D, Jungnickel B, Kehlenbach RH, Oswald F, Englert C, Kaether C. The nuclear pore proteins Nup88/214 and T-ALL-associated NUP214 fusion proteins regulate Notch signaling. J Biol Chem. 2019 Jun 11. pii: jbc.RA118.006357. doi: 10.1074/jbc.RA118.006357. [Epub ahead of print].

Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis

Authors:
Page DJ, Thuret R, Venkatraman L, Takahashi T, Bentley K, Herbert SP
Citation:
Cell Rep. 2019 Jun 11;27(11):3139-3151.e5. doi: 10.1016/j.celrep.2019.05.052
Epub:
Not Epub
Abstract:
Angiogenesis is driven by the coordinated collective branching of specialized leading "tip" and trailing "stalk...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Page DJ, Thuret R, Venkatraman L, Takahashi T, Bentley K, Herbert SP. Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis. Cell Rep. 2019 Jun 11;27(11):3139-3151.e5. doi: 10.1016/j.celrep.2019.05.052.

Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas

Authors:
Delacruz RGC, Sandoval IT, Chang K, Miller BN, Reyes-Uribe L, Borras E, Lynch PM, Taggart MW, Hawk ET, Vilar E, Jones DA
Citation:
Oncotarget. 2019 Jun 11;10(39):3939-3951. doi: 10.18632/oncotarget.27003. eCollection 2019 Jun 11
Epub:
Not Epub
Abstract:
Germline mutations in the tumor suppressor Adenomatous Polyposis Coli (APC) define Familial Adenomatous Polyposis (FAP), the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Delacruz RGC, Sandoval IT, Chang K, Miller BN, Reyes-Uribe L, Borras E, Lynch PM, Taggart MW, Hawk ET, Vilar E, Jones DA. Functional characterization of CNOT3 variants identified in familial adenomatous polyposis adenomas. Oncotarget. 2019 Jun 11;10(39):3939-3951. doi: 10.18632/oncotarget.27003. eCollection 2019 Jun 11.

Robo2 regulates synaptic oxytocin content by affecting actin dynamics

Authors:
Anbalagan S, Blechman J, Gliksberg M, Gordon L, Rotkopf R, Dadosh T, Shimoni E, Levkowitz G
Citation:
Elife. 2019 Jun 10;8. pii: e45650. doi: 10.7554/eLife.45650
Epub:
Not Epub
Abstract:
The regulation of neuropeptide level at the site of release is essential for proper neurophysiological functions. We focused on...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anbalagan S, Blechman J, Gliksberg M, Gordon L, Rotkopf R, Dadosh T, Shimoni E, Levkowitz G. Robo2 regulates synaptic oxytocin content by affecting actin dynamics. Elife. 2019 Jun 10;8. pii: e45650. doi: 10.7554/eLife.45650.

Vitamin D Receptor Signaling Regulates Craniofacial Cartilage Development in Zebrafish

Authors:
Kwon HJ
Citation:
J Dev Biol. 2019 Jun 22;7(2). pii: E13. doi: 10.3390/jdb7020013
Epub:
Not Epub
Abstract:
Vitamin D plays essential roles in supporting the skeletal system. The active form of vitamin D functions through the vitamin D...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kwon HJ. Vitamin D Receptor Signaling Regulates Craniofacial Cartilage Development in Zebrafish. J Dev Biol. 2019 Jun 22;7(2). pii: E13. doi: 10.3390/jdb7020013.

Novel TRRAP mutation causes autosomal dominant non-syndromic hearing loss

Authors:
Xia W, Hu J, Ma J, Huang J, Wang X, Jiang N, Zhang J, Ma Z, Ma D
Citation:
Clin Genet. 2019 Jun 23. doi: 10.1111/cge.13590. [Epub ahead of print]
Epub:
Yes
Abstract:
Hereditary non-syndromic hearing loss is the most common inherited sensory defect in humans. More than 40 genes have been...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xia W, Hu J, Ma J, Huang J, Wang X, Jiang N, Zhang J, Ma Z, Ma D. Novel TRRAP mutation causes autosomal dominant non-syndromic hearing loss. Clin Genet. 2019 Jun 23. doi: 10.1111/cge.13590. [Epub ahead of print].

Exploring Site-specific Activation of Bis-N,N'-Dialkylaminophosphordiamidites and the Synthesis of Morpholinophosphoramidate Oligonucleotides

Authors:
Krishna H, Jastrzebska K, Caruthers M
Citation:
FEBS Lett. 2019 Jun 17. doi: 10.1002/1873-3468.13492. [Epub ahead of print]
Epub:
Yes
Abstract:
Morpholinos are six-membered rings that may provide higher conformational rigidity when incorporated into an oligonucleotide (...
Citation Extract:
Krishna H, Jastrzebska K, Caruthers M. Exploring Site-specific Activation of Bis-N,N'-Dialkylaminophosphordiamidites and the Synthesis of Morpholinophosphoramidate Oligonucleotides. FEBS Lett. 2019 Jun 17. doi: 10.1002/1873-3468.13492. [Epub ahead of print].

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