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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
Brain aromatase modulates cardiac functions in embryonic zebrafish
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Citation:
Int J Vet Sci Med. 2019;7(1):31-4. doi:10.1080/23144599.2019.1675287 Epub:
Not Epub Abstract:
Oestradiol (E2) is known as a female reproductive hormone with pleiotropic effects on the cardiovascular system. Local E2... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ulhaq ZS. Brain aromatase modulates cardiac functions in embryonic zebrafish. Int J Vet Sci Med. 2019;7(1):31-4. doi:10.1080/23144599.2019.1675287. |
Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients
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Citation:
Dis Model Mech. 2019;[Epub] doi:10.1242/dmm.041103 Epub:
Yes Abstract:
Hypertrophic cardiomyopathy (HCM) is a hereditary disease characterized by cardiac hypertrophy with diastolic dysfunction. Gene... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Higashikuse Y, Mittal N, Arimura T, Yoon SH, Oda M, Enomoto H, Kaneda R, Fumiyuki Hattori F, Suzuki T, Kawakami A, Gasch A, Furukawa T, Labeit S, Fukuda K, Kimura A, Makino S. Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients. Dis Model Mech. 2019;[Epub] doi:10.1242/dmm.041103. |
MicroRNAs Establish the Right-Handed Dominance of the Heart Laterality Pathway in Vertebrates
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Citation:
Dev Cell. 2019 Oct 17. pii: S1534-5807(19)30768-3. doi: 10.1016/j.devcel.2019.09.012. [Epub ahead of print] Epub:
Not Epub Abstract:
Despite their external bilateral symmetry, vertebrates have internal left/right (L/R) asymmetries required for optimal organ... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rago L, Castroviejo N, Fazilaty H, Garcia-Asencio F, Ocaña OH, Galcerán J, Nieto MA. MicroRNAs Establish the Right-Handed Dominance of the Heart Laterality Pathway in Vertebrates. Dev Cell. 2019 Oct 17. pii: S1534-5807(19)30768-3. doi: 10.1016/j.devcel.2019.09.012. [Epub ahead of print]. |
YWHA (14-3-3) protein isoforms and their interactions with CDC25B phosphatase in mouse oogenesis and oocyte maturation
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Citation:
BMC Dev Biol. 2019 Oct 22;19(1):20. doi: 10.1186/s12861-019-0200-1 Epub:
Not Epub Abstract:
BACKGROUND: Immature mammalian oocytes are held arrested at prophase I of meiosis by an inhibitory phosphorylation of cyclin-... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Eisa AA, De S, Detwiler A, Gilker E, Ignatious AC, Vijayaraghavan S, Kline D. YWHA (14-3-3) protein isoforms and their interactions with CDC25B phosphatase in mouse oogenesis and oocyte maturation. BMC Dev Biol. 2019 Oct 22;19(1):20. doi: 10.1186/s12861-019-0200-1. |
Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation
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Citation:
Cancer Immunol Immunother. 2019 Oct 18. doi: 10.1007/s00262-019-02397-7. [Epub ahead of print] Epub:
Yes Abstract:
Antibodies targeting the T-cell immune checkpoint cytotoxic T-lymphocyte antigen-4 (CTLA4) enhance the effectiveness of... Delivery Method:
oligo bathing; injection Organism or Cell Type:
cell culture: human T cells; C57BL/6 mice with B16F10 melanomas Citation Extract: Schwartz AL, Nath PR, Allgauer M, Lessey-Morillon EC, Sipes JM, Ridnour LA, Morillon Ii YM, Yu Z, Restifo NP, Roberts DD. Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation. Cancer Immunol Immunother. 2019 Oct 18. doi: 10.1007/s00262-019-02397-7. [Epub ahead of print]. |
Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies
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Citation:
Front Physiol. 2019 Sep 20;10:1197. doi:10.3389/fphys.2019.01197. eCollection 2019 Epub:
Not Epub Abstract:
Congenital heart disease (CHD) is a significant cause of mortality in infants and adults. Currently human genomic analysis has... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Deniz E, Jonas S, Khokha MK, Choma MA. Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies. Front Physiol. 2019 Sep 20;10:1197. doi:10.3389/fphys.2019.01197. eCollection 2019. |
Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish
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Citation:
JCI Insight. 2019;4(20:e121971. doi:10.1172/jci.insight.121971 Epub:
Not Epub Abstract:
Deterioration or inborn malformations of the cardiac conduction system (CCS) interfere with proper impulse propagation in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann W-H, Wess J, Kühl M, Hoffmann C, Tilley DG, Philipp M. Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. JCI Insight. 2019;4(20:e121971. doi:10.1172/jci.insight.121971. |
Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia
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Citation:
G3 (Bethesda). 2019;9(10):[Epub] doi:10.1534/g3.119.400585 Epub:
Yes Abstract:
Ribosome is a vital molecular machine for protein translation in the cell. Defects in several ribosomal proteins including... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng Chen, Haigen Huang, Ruibin Yan, Shuo Lin and Wei Qin. Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia. G3 (Bethesda). 2019;9(10):[Epub] doi:10.1534/g3.119.400585. |
Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo
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Citation:
Nat Comm. 2019;10(1):4710. doi:10.1038/s41467-019-12609-4 Epub:
Not Epub Abstract:
Morphogen signalling forms an activity gradient and instructs cell identities in a signalling strength-dependent manner to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, Masuda T, Shimizu N, Ohkawa Y, Ishitani T. Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Nat Comm. 2019;10(1):4710. doi:10.1038/s41467-019-12609-4. |
An adhesion code ensures robust pattern formation during tissue morphogenesis
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Citation:
bioRxiv. 2019:[preprint] doi:10.1101/803635 Epub:
Not Epub Abstract:
An outstanding question in embryo development is how spatial patterns are formed robustly. In the zebrafish spinal cord, neural... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tsai TY-C, Sikora M, Xia P, Colak-Champollion T, Knaut H, Heisenberg C-P, Megason SG. An adhesion code ensures robust pattern formation during tissue morphogenesis. bioRxiv. 2019:[preprint] doi:10.1101/803635. |