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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
Human colonic EVs induce murine enteric neuroplasticity via the lncRNA GAS5/miR-23/NMDA NR2B axis
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Citation:
JCI Insight. 2025 Mar 10;10(5):e178631. doi: 10.1172/jci.insight.178631. PMID: 40059833 Epub:
Not Epub Abstract:
Postinfectious, diarrhea-predominant, irritable bowel syndrome (PI-IBS-D) is difficult to treat owing to its unknown... Delivery Method:
Vivo-Morpholino; intraperitoneal (i.p.) Organism or Cell Type:
Rab27a/b–/– mice Citation Extract: Zhou Q, Yang L, Verne ZT, Zhang BB, Fields JZ, Thacker AT, Verne GN. Human colonic EVs induce murine enteric neuroplasticity via the lncRNA GAS5/miR-23/NMDA NR2B axis. JCI Insight. 2025 Mar 10;10(5):e178631. doi: 10.1172/jci.insight.178631. PMID: 40059833. |
Srebf2 mediates successful optic nerve axon regeneration via the mevalonate synthesis pathway
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Citation:
Mol Neurodegener. 2025 Mar 5;20(1):28. doi: 10.1186/s13024-025-00807-2. PMID: 40045384; PMCID: PMC11883989 Epub:
Not Epub Abstract:
Background: Axon regeneration within the mammalian central nervous system is extremely limited. In optic neuropathy conditions... Delivery Method:
gel foam soaked in MO placed on distal optic nerve stump Organism or Cell Type:
zebrafish Citation Extract: Hu M, Veldman MB. Srebf2 mediates successful optic nerve axon regeneration via the mevalonate synthesis pathway. Mol Neurodegener. 2025 Mar 5;20(1):28. doi: 10.1186/s13024-025-00807-2. PMID: 40045384; PMCID: PMC11883989. |
Protein-O-fucosylation of co-receptors may be required for Nodal signaling in Xenopus
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Citation:
Mol Cells. 2025 Mar 3:100207. doi: 10.1016/j.mocell.2025.100207. Epub ahead of print. PMID: 40043779 Epub:
Not Epub Abstract:
Nodal-related ligands of TGF-β family play pivotal roles for mesoderm induction and body axis formation during vertebrate early... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kim YJ, Nho SJ, Lee SY, Yeo CY. Protein-O-fucosylation of co-receptors may be required for Nodal signaling in Xenopus. Mol Cells. 2025 Mar 3:100207. doi: 10.1016/j.mocell.2025.100207. Epub ahead of print. PMID: 40043779. |
mRNA splicing variants of the transcription factor Blimp1 differentially regulate germline genes in echinoderms
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Citation:
Dev Biol. 2025 Feb 28:S0012-1606(25)00054-5 Epub:
Not Epub Abstract:
Germ cell specification is an essential step in sexually reproducing animals. Echinoderms possess diverse representatives of... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin), Patiria miniata (sea star) Citation Extract: Reyes G, Oulhen N, Wessel G. mRNA splicing variants of the transcription factor Blimp1 differentially regulate germline genes in echinoderms. Dev Biol. 2025 Feb 28:S0012-1606(25)00054-5. |
RPS24 haploinsufficiency impairs erythropoiesis in the Diamond-Blackfan anemia zebrafish model via the STAT6-SATB1 pathway
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Citation:
Biochem Biophys Res Commun. 2025 Apr 5;756:151563. doi: 10.1016/j.bbrc.2025.151563. Epub 2025 Mar 1. PMID: 40054062 Epub:
Not Epub Abstract:
Diamond-Blackfan anemia (DBA) is a rare bone marrow failure disorder primarily caused by mutations in ribosomal proteins (RPs... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ahn S, Oh CK. R. RPS24 haploinsufficiency impairs erythropoiesis in the Diamond-Blackfan anemia zebrafish model via the STAT6-SATB1 pathway. Biochem Biophys Res Commun. 2025 Apr 5;756:151563. doi: 10.1016/j.bbrc.2025.151563. Epub 2025 Mar 1. PMID: 40054062. |
Phosphorodiamidate Morpholino Oligomers-Loaded Nanobubbles for Ultrasound-Mediated Delivery to the Myocardium in Muscular Dystrophy
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Citation:
ACS Omega Article ASAP. doi: 10.1021/acsomega.4c10896 Epub:
Not Epub Abstract:
Microbubbles (MBs) and nanobubbles (NBs) can oscillate and collapse in response to ultrasound exposure, resulting in contrast... Delivery Method:
R8 peptide-linked; intravenous (i.v.) injection Organism or Cell Type:
mice: C57BL/10ScSnmdx Citation Extract: Endo-Takahashi Y, Sakurai A, Oguri Y, Katagiri F, Akiyama S, Sashida S, Yamaguchi T, Marunouchi T, Suzuki R, Maruyama K, Tanonaka K, Nomizu M, Negishi Y. Phosphorodiamidate Morpholino Oligomers-Loaded Nanobubbles for Ultrasound-Mediated Delivery to the Myocardium in Muscular Dystrophy. ACS Omega Article ASAP. doi: 10.1021/acsomega.4c10896. |
Optochemical control over mRNA translation by photocaged phosphorodiamidate morpholino oligonucleotides in vivo
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Citation:
Nat Commun 16, 3614 (2025). https://doi.org/10.1038/s41467-025-58207-5 Epub:
Not Epub Abstract:
A key regulatory step in protein synthesis is the initiation of mRNA translation. We developed an efficient, robust, and... Delivery Method:
microinjection, UV-photocleavable Morpholino Organism or Cell Type:
zebrafish Citation Extract: Tarbashevich K, Ghosh A, Das A, Kuilya D, Shrama SN, Sinha S, Raz E. Optochemical control over mRNA translation by photocaged phosphorodiamidate morpholino oligonucleotides in vivo. Nat Commun 16, 3614 (2025). https://doi.org/10.1038/s41467-025-58207-5. |
NDUFB7 mutations cause brain neuronal defects, lactic acidosis, and mitochondrial dysfunction in humans and zebrafish
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Citation:
Cell Death Discov. 2025 Mar 1;11(1):82. doi: 10.1038/s41420-025-02369-0. PMID: 40025060 Epub:
Not Epub Abstract:
Complex I of the mitochondrial electron transfer chain is one of the largest membrane protein assemblies ever discovered. A... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen YL, Chung BH, Mimaki M, Uchino S, Chien YH, Mak CC, Peng SS, Wang WC, Lin YL, Hwu WL, Lee SJ, Lee NC. NDUFB7 mutations cause brain neuronal defects, lactic acidosis, and mitochondrial dysfunction in humans and zebrafish. Cell Death Discov. 2025 Mar 1;11(1):82. doi: 10.1038/s41420-025-02369-0. PMID: 40025060. |
Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis
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Citation:
Nat Commun. 2025 Feb 21;16(1):1833. doi: 10.1038/s41467-025-56889-5. PMID: 39979259; PMCID: PMC11842872 Epub:
Not Epub Abstract:
The three-dimensional folding of chromosomes is essential for nuclear functions such as DNA replication and gene regulation.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Coßmann J, Kos PI, Varamogianni-Mamatsi V, Assenheimer DS, Bischof TA, Kuhn T, Vomhof T, Papantonis A, Giorgetti L, Gebhardt JCM. Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis. Nat Commun. 2025 Feb 21;16(1):1833. doi: 10.1038/s41467-025-56889-5. PMID: 39979259; PMCID: PMC11842872. |
Nance-Horan-syndrome-like 1b controls mesodermal cell migration by regulating protrusion and actin dynamics during zebrafish gastrulation
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Citation:
Commun Biol. 2025 Feb 28;8(1):328. doi: 10.1038/s42003-025-07689-6. PMID: 40021913; PMCID: PMC11871229 Epub:
Not Epub Abstract:
Cell migrations are crucial for embryonic development, wound healing, the immune response, as well as for cancer progression.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Escot S, Hassanein Y, Elouin A, Torres-Paz J, Mellottee L, Ignace A, David NB. Nance-Horan-syndrome-like 1b controls mesodermal cell migration by regulating protrusion and actin dynamics during zebrafish gastrulation. Commun Biol. 2025 Feb 28;8(1):328. doi: 10.1038/s42003-025-07689-6. PMID: 40021913; PMCID: PMC11871229. |