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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

A newly identified Rab-GDI paralogue has a role in neural development in amphibia

Authors:
Nazlamova L, Noble A, Schubert FR, McGeehan J, Myers F, Guille M, Scarlett G
Citation:
Gene. 2017 Jan 30;599:78-86. doi: 10.1016/j.gene.2016.11.013. Epub 2016 Nov 9
Epub:
Not Epub
Abstract:
Vesicle shuttling is critical for many cellular and organismal processes, including embryonic development. GDI proteins...
Organism or Cell Type:
Xenopus
Citation Extract:
Nazlamova L, Noble A, Schubert FR, McGeehan J, Myers F, Guille M, Scarlett G. A newly identified Rab-GDI paralogue has a role in neural development in amphibia. Gene. 2017 Jan 30;599:78-86. doi: 10.1016/j.gene.2016.11.013. Epub 2016 Nov 9.

Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation

Authors:
Feng D, Wang J, Yang W, Li J, Lin X, Zha F, Wang X, Ma L, Choi NT, Mii Y, Takada S, Huen MSY, Guo Y, Zhang L, Gao B
Citation:
Sci Adv. 2021 May 14;7(20):eabg2099. doi: 10.1126/sciadv.abg2099. Print 2021 May
Epub:
Not Epub
Abstract:
The four-pass transmembrane proteins Vangl1 and Vangl2 are dedicated core components of Wnt/planar cell polarity (Wnt/PCP)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Feng D, Wang J, Yang W, Li J, Lin X, Zha F, Wang X, Ma L, Choi NT, Mii Y, Takada S, Huen MSY, Guo Y, Zhang L, Gao B. Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation. Sci Adv. 2021 May 14;7(20):eabg2099. doi: 10.1126/sciadv.abg2099. Print 2021 May.

Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish

Authors:
Mishima Y, Han P, Kimura S, Iwasaki S
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443743
Epub:
Not Epub
Abstract:
The control of mRNA stability plays a central role in regulating gene expression patterns. Recent studies have revealed that...
Organism or Cell Type:
zebrafish
Citation Extract:
Mishima Y, Han P, Kimura S, Iwasaki S. Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443743.

The STING ligand 2′3′-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis

Authors:
Margolis SR, Dietzen PA, Hayes BM, Wilson SC, Remick BC, Chou S, Vance RE
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.13.443009
Epub:
Not Epub
Abstract:
In mammals, the cGAS-cGAMP-STING pathway is crucial for sensing viral infection and initiating an anti-viral type I interferon...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (anemone)
Citation Extract:
Margolis SR, Dietzen PA, Hayes BM, Wilson SC, Remick BC, Chou S, Vance RE. The STING ligand 2′3′-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.13.443009.

Slit2 is necessary for optic axon organization in the zebrafish ventral midline

Authors:
Davison C, Zolessi FR
Citation:
Cells Dev. 2021 Apr 10;166:203677. doi: 10.1016/j.cdev.2021.203677. Online ahead of print
Epub:
Not Epub
Abstract:
Slit-Robo signaling has been implicated in regulating several steps of retinal ganglion cell axon guidance, with a central role...
Organism or Cell Type:
zebrafish
Citation Extract:
Davison C, Zolessi FR. Slit2 is necessary for optic axon organization in the zebrafish ventral midline. Cells Dev. 2021 Apr 10;166:203677. doi: 10.1016/j.cdev.2021.203677. Online ahead of print.

Role of vertebrate GAGA associated factor (vGAF) in early development of zebrafish

Authors:
Matharu NK, Yadav S, Kumar M, Mishra RK
Citation:
Cells Dev. 2021 Apr 24;166:203682. doi: 10.1016/j.cdev.2021.203682. Online ahead of print
Epub:
Not Epub
Abstract:
Homeotic genes and their genomic organization show remarkable conservation across bilaterians. Consequently, the regulatory...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matharu NK, Yadav S, Kumar M, Mishra RK. Role of vertebrate GAGA associated factor (vGAF) in early development of zebrafish. Cells Dev. 2021 Apr 24;166:203682. doi: 10.1016/j.cdev.2021.203682. Online ahead of print.

Molluscan dorsal-ventral patterning relying on bmp2/4 and chordin provides insights into spiralian development and bilaterian evolution

Authors:
Tan S, Huan P, Liu B
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.11.245670
Epub:
Not Epub
Abstract:
Although a conserved mechanism relying on bmp2/4 and chordin is suggested in animal dorsal-ventral (DV) patterning, this...
Delivery Method:
microinjection
Organism or Cell Type:
Lottia goshimai (mollusk)
Citation Extract:
Tan S, Huan P, Liu B. Molluscan dorsal-ventral patterning relying on bmp2/4 and chordin provides insights into spiralian development and bilaterian evolution. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.11.245670 .

Targeted SMN Exon Skipping: A Useful Control to Assess In Vitro and In Vivo Splice-Switching Studies

Authors:
Flynn LL, Mitrpant C, Adams A, Pitout IL, Stirnweiss A, Fletcher S, Wilton SD
Citation:
Biomedicines. 2021;9(5):552. doi:10.3390/biomedicines9050552
Epub:
Not Epub
Abstract:
The literature surrounding the use of antisense oligonucleotides continues to grow, with new disease and mechanistic...
Delivery Method:
cell bathing, subcutaneous and intraperitoneal (s.c. & i.p.) injection
Organism or Cell Type:
cell culture: human fibroblasts, SH-SY5Y neuroblastoma, mdx myoblasts; mice
Citation Extract:
Flynn LL, Mitrpant C, Adams A, Pitout IL, Stirnweiss A, Fletcher S, Wilton SD. Targeted SMN Exon Skipping: A Useful Control to Assess In Vitro and In Vivo Splice-Switching Studies. Biomedicines. 2021;9(5):552. doi:10.3390/biomedicines9050552.

Insm1-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone Nematostella vectensis

Authors:
Tournière O, Busengdal H, Gahan JM, Rentzsch F
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439178
Epub:
Not Epub
Abstract:
Neurons are highly specialized cells present in nearly all animals, but their evolutionary origin and relationship to other...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Tournière O, Busengdal H, Gahan JM, Rentzsch F. Insm1-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone Nematostella vectensis. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439178.

Myeloid and endothelial cells cooperate to promote hematopoietic stem cells expansion in the fetal niche

Authors:
Cacialli P, Mailhe M-P, Golub R, Bertrand JY
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.07.438809
Epub:
Not Epub
Abstract:
During embryonic development, very few hematopoietic stem cells (HSCs) are produced from the hemogenic endothelium, that will...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cacialli P, Mailhe M-P, Golub R, Bertrand JY. Myeloid and endothelial cells cooperate to promote hematopoietic stem cells expansion in the fetal niche. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.07.438809.

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