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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
A somatic piRNA pathway regulates epithelial-to-mesenchymal transition of chick neural crest cells
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.30.442165 Epub:
Not Epub Abstract:
In the metazoan germline, Piwi proteins play an essential regulatory role in maintenance of stemness and self-renewal by piRNA-... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Galton R, Fejes-Toth K, Bronner ME. A somatic piRNA pathway regulates epithelial-to-mesenchymal transition of chick neural crest cells. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.30.442165 . |
Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish
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Citation:
Int J Mol Sci. 2021;22:4832. doi:10.3390/ijms22094832 Epub:
Not Epub Abstract:
The BH3-only molecule Bad regulates cell death via its differential protein phosphorylation, but very few studies address its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hung J-C, Wu J-L, Hong J-R. Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish. Int J Mol Sci. 2021;22:4832. doi:10.3390/ijms22094832. |
Blood vessels regulate primary motor neuronal pathfinding in zebrafish via exosome contained microRNA-22
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.29.441918 Epub:
Not Epub Abstract:
A precise neuro-vascular communication is crucial to orchestrate directional migration and patterning of the complex vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sheng J, Gong J, Shi Y, Wang X, Liu D. Blood vessels regulate primary motor neuronal pathfinding in zebrafish via exosome contained microRNA-22. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.29.441918 . |
Guidance by followers ensures long-range coordination of cell migration through α-Catenin mechanoperception
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.26.441407 Epub:
Not Epub Abstract:
Morphogenesis, wound healing and some cancer metastases depend upon migration of cell collectives that need to be guided to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Boutillon A, Jahn D, González-Tirado S, Starruß J, Brusch L, David NB. Guidance by followers ensures long-range coordination of cell migration through α-Catenin mechanoperception. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.26.441407. |
Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway
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Citation:
Development. 2021 Apr 28:dev.199441. doi: 10.1242/dev.199441. Online ahead of print Epub:
Yes Abstract:
The focal adhesion protein Kindlin2 is essential for integrin activation, a process that is fundamental to cell-extracellular... Organism or Cell Type:
Xenopus Citation Extract: Wang H, Wang C, Long Q, Zhang Y, Wang M, Liu J, Qi X, Cai D, Lu G, Sun J, Yao YG, Chan WY, Chan WY, Deng Y, Zhao H. Kindlin2 regulates neural crest specification via integrin-independent regulation of the FGF signaling pathway. Development. 2021 Apr 28:dev.199441. doi: 10.1242/dev.199441. Online ahead of print. |
A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis
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Citation:
J Clin Endocrinol Metab. 2021 Apr 29:dgab283. doi: 10.1210/clinem/dgab283. Online ahead of print Epub:
Yes Abstract:
Context: Iodide transport defect (ITD) (Online Mendelian Inheritance in Man #274400) is an uncommon cause of dyshormonogenic... Organism or Cell Type:
zebrafish Citation Extract: Martín M, Modenutti CP, Gil Rosas ML, Peyret V, Geysels RC, Bernal Barquero CE, Sobrero G, Muñoz L, Signorino M, Testa G, Miras MB, Masini-Repiso AM, Calcaterra NB, Coux G, Carrasco N, Martí MA, Nicola JP. A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis. J Clin Endocrinol Metab. 2021 Apr 29:dgab283. doi: 10.1210/clinem/dgab283. Online ahead of print. |
The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin
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Citation:
Nat Cell Biol. 2020 Nov;22(11):1332-1345. doi: 10.1038/s41556-020-00595-5 Epub:
Not Epub Abstract:
Dystrophin proteomic regulation in muscular dystrophies (MDs) remains unclear. We report that a long noncoding RNA (lncRNA),... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Zhang Y, Li Y, Hu Q, Xi Y, Xing Z, Zhang Z, Huang L, Wu J, Liang K, Nguyen TK, Egranov SD, Sun C, Zhao Z, Hawke DH, Li J, Sun D, Kim JJ, Zhang P, Cheng J, Farida A, Hung MC, Han L, Darabi R, Lin C, Yang L. The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin. Nat Cell Biol. 2020 Nov;22(11):1332-1345. doi: 10.1038/s41556-020-00595-5. |
Wnt signaling and tbx16 form a bistable switch to commit bipotential progenitors to mesoderm
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Citation:
Development. 2015 Jul 15;142(14):2499-507. doi: 10.1242/dev.124024. Epub 2015 Jun 10 Epub:
Not Epub Abstract:
Anterior to posterior growth of the vertebrate body is fueled by a posteriorly located population of bipotential neuro-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bouldin CM, Manning AJ, Peng YH, Farr GH 3rd, Hung KL, Dong A, Kimelman D. Wnt signaling and tbx16 form a bistable switch to commit bipotential progenitors to mesoderm. Development. 2015 Jul 15;142(14):2499-507. doi: 10.1242/dev.124024. Epub 2015 Jun 10. |
Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations
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Citation:
Mol Ther. 2021;29(8)2441-55. doi: 10.1016/j.ymthe.2021.04.024. Online ahead of print Epub:
Not Epub Abstract:
Mutations in USH2A are among the most common causes of syndromic and non-syndromic retinitis pigmentosa (RP). The two most... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dulla K, Slijkerman R, van Diepen HC, Albert S, Dona M, Beumer W, Turunen JJ, Chan HL, Schulkens IA, Vorthoren L, Besten CD, Buil L, Schmidt I, Miao J, Venselaar H, Zang J, Neuhauss SCF, Peters T, Broekman S, Pennings R, Kremer H, Platenburg G, Adamson P, de Vrieze E, van Wijk E. Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations. Mol Ther. 2021;29(8)2441-55. doi: 10.1016/j.ymthe.2021.04.024. Online ahead of print. |
Pinhead antagonizes Admp to promote notochord formation
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.21.440817 Epub:
Not Epub Abstract:
Dorsoventral patterning of a vertebrate embryo critically depends on the activity of Smad1 that mediates signaling by several... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Itoh K, Ossipova O, Sokol S. Pinhead antagonizes Admp to promote notochord formation. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.21.440817. |