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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome

Authors:
Stoetzel C, Muller J, Laurier V, Davis EE, Zaghloul NA, Vicaire S, Jacquelin C, Plewniak F, Leitch CC, Sarda P, Hamel C, de Ravel TJ, Lewis RA, Friederich E, Thibault C, Danse JM, Verloes A, Bonneau D, Katsanis N, Poch O, Mandel JL, Dollfus H
Citation:
Am J Hum Genet. 2007 Jan;80(1):1-11. Epub 2006 Nov 15
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is primarily an autosomal recessive ciliopathy characterized by progressive retinal degeneration,...
Organism or Cell Type:
zebrafish
Citation Extract:
Stoetzel C, Muller J, Laurier V, Davis EE, Zaghloul NA, Vicaire S, Jacquelin C, Plewniak F, Leitch CC, Sarda P, Hamel C, de Ravel TJ, Lewis RA, Friederich E, Thibault C, Danse JM, Verloes A, Bonneau D, Katsanis N, Poch O, Mandel JL, Dollfus H. Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome. Am J Hum Genet. 2007 Jan;80(1):1-11. Epub 2006 Nov 15.

Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localisation of polycystin-2 in vivo and in vitro

Authors:
Streets AJ, Moon DJ, Kane ME, Obara T, Ong AC
Citation:
Hum Mol Genet. 2006 May 1;15(9):1465-73. Epub 2006 Mar 21.
Epub:
Not Epub
Abstract:
PKD2 is mutated in 15% of patients with autosomal dominant polycystic kidney disease (ADPKD). Polycystin-2 (PC2), the PKD2...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Streets AJ, Moon DJ, Kane ME, Obara T, Ong AC. Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localisation of polycystin-2 in vivo and in vitro. Hum Mol Genet. 2006 May 1;15(9):1465-73. Epub 2006 Mar 21..

IFATS Series: Stem Cell Antigen-1 Positive Ear Mesenchymal Stem Cells (EMSC) Display Enhanced Adipogenic Potential

Authors:
Staszkiewicz J, Gimble J, Manuel JA, Gawronska-Kozak B
Citation:
Stem Cells. 2008 Jul 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Hyperplasia is a major contributor to the increase in adipose tissue mass that is characteristic of obesity. However, the...
Organism or Cell Type:
Ear mesenchymal stem cells (EMSC)
Citation Extract:
Staszkiewicz J, Gimble J, Manuel JA, Gawronska-Kozak B. IFATS Series: Stem Cell Antigen-1 Positive Ear Mesenchymal Stem Cells (EMSC) Display Enhanced Adipogenic Potential. Stem Cells. 2008 Jul 3. [Epub ahead of print].

In vivo and in vitro assessment of cardiac beta-adrenergic receptors in larval zebrafish (Danio rerio)

Authors:
Steele SL, Yang X, Debiais-Thibaud M, Schwerte T, Pelster B, Ekker M, Tiberi M, Perry SF
Citation:
J Exp Biol. 2011 May 1;214(Pt 9):1445-1457
Epub:
Not Epub
Abstract:
β-Adrenergic receptors (βARs) are crucial for maintaining the rate and force of cardiac muscle contraction in vertebrates....
Organism or Cell Type:
zebrafish
Citation Extract:
Steele SL, Yang X, Debiais-Thibaud M, Schwerte T, Pelster B, Ekker M, Tiberi M, Perry SF. In vivo and in vitro assessment of cardiac beta-adrenergic receptors in larval zebrafish (Danio rerio). J Exp Biol. 2011 May 1;214(Pt 9):1445-1457.

Inhibition of Muscle Differentiation by the Novel Muscleblind-Related Protein CHCR

Authors:
Squillace R, Chenault D, Wang E
Citation:
Dev Biol. 2002 Oct 1;250(1):218
Epub:
Not Epub
Abstract:
Growth factor withdrawal from proliferating myoblasts induces the expression of muscle-specific genes essential for myogenesis...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: C2C12 cells
Citation Extract:
Squillace R, Chenault D, Wang E. Inhibition of Muscle Differentiation by the Novel Muscleblind-Related Protein CHCR. Dev Biol. 2002 Oct 1;250(1):218.

Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers

Authors:
Stein DA
Citation:
Curr Pharm Des. 2008;14(25):2619-34
Epub:
Not Epub
Abstract:
RNA virus infections cause immense human disease burdens globally, and few effective antiviral drugs are available for their...
Delivery Method:
peptide-coupled
Citation Extract:
Stein DA. Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers. Curr Pharm Des. 2008;14(25):2619-34.

Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers

Authors:
Stein DA, Skilling DE, Iversen PL, Smith AW
Citation:
Antisense Nucleic Acid Drug Dev. 2001 Oct;11(5):317-25
Epub:
Not Epub
Abstract:
Caliciviruses infect and cause disease in animals and humans. They are nonenveloped, positive-stranded RNA viruses with a...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: PK-15 and Vero cells
Citation Extract:
Stein DA, Skilling DE, Iversen PL, Smith AW. Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers. Antisense Nucleic Acid Drug Dev. 2001 Oct;11(5):317-25.

Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transition in starfish eggs

Authors:
Tachibana K, Mori M, Matsuhira T, Karino T, Inagaki T, Nagayama A, Nishiyama A, Hara M, Kishimoto T
Citation:
Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5006-11. Epub 2010 Feb 25
Epub:
Not Epub
Abstract:
Initiation of DNA replication in eukaryotic cells is controlled through an ordered assembly of protein complexes at replication...
Delivery Method:
Microinjection
Organism or Cell Type:
Starfish Asterina pectinifera
Citation Extract:
Tachibana K, Mori M, Matsuhira T, Karino T, Inagaki T, Nagayama A, Nishiyama A, Hara M, Kishimoto T. Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transition in starfish eggs. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5006-11. Epub 2010 Feb 25.

Interplay between Etsrp/ER71, scl and alk8 signaling controls endothelial and myeloid cell formation

Authors:
Sumanas S, Gomez G, Zhao Y, Park C, Choi K, Lin S
Citation:
Blood. 2008 May 1;111(9):4500-10. Epub 2008 Feb 12.
Epub:
Not Epub
Abstract:
Vascular endothelial and myeloid cells have been proposed to originate from a common precursor cell, hemangioblast. Mechanism...
Organism or Cell Type:
zebrafish
Citation Extract:
Sumanas S, Gomez G, Zhao Y, Park C, Choi K, Lin S. Interplay between Etsrp/ER71, scl and alk8 signaling controls endothelial and myeloid cell formation. Blood. 2008 May 1;111(9):4500-10. Epub 2008 Feb 12..

Intracellular inactivation of specific nucleotide sequences: a general approach to the treatment of viral diseases and virally-mediated cancers

Authors:
Summerton J
Citation:
J Theor Biol 1979 May 7;78(1):61-75. doi:10.1016/0022-5193(79)90327-8
Epub:
Not Epub
Abstract:
A general approach is proposed for development of anti-viral complexes capable of specific intracellular inactivation of viral...
Citation Extract:
Summerton J. Intracellular inactivation of specific nucleotide sequences: a general approach to the treatment of viral diseases and virally-mediated cancers. J Theor Biol 1979 May 7;78(1):61-75. doi:10.1016/0022-5193(79)90327-8.

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