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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Mutations in B3GALNT2 Cause Congenital Muscular Dystrophy and Hypoglycosylation of α-Dystroglycan

Authors:
Stevens E, Carss KJ, Cirak S, Foley AR, Torelli S, Willer T, Tambunan DE, Yau S, Brodd L, Sewry CA, Feng L, Haliloglu G, Orhan D, Dobyns WB, Enns GM, Manning M, Krause A, Salih MA, Walsh CA, Hurles M, Campbell KP, Manzini MC; UK10K Consortium, Stemple D, Lin YY, Muntoni F
Citation:
Am J Hum Genet. 2013 Feb 26. doi:pii: S0002-9297(13)00069-4. 10.1016/j.ajhg.2013.01.016. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations in several known or putative glycosyltransferases cause glycosylation defects in α-dystroglycan (α-DG), an integral...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stevens E, Carss KJ, Cirak S, Foley AR, Torelli S, Willer T, Tambunan DE, Yau S, Brodd L, Sewry CA, Feng L, Haliloglu G, Orhan D, Dobyns WB, Enns GM, Manning M, Krause A, Salih MA, Walsh CA, Hurles M, Campbell KP, Manzini MC; UK10K Consortium, Stemple D, Lin YY, Muntoni F . Mutations in B3GALNT2 Cause Congenital Muscular Dystrophy and Hypoglycosylation of α-Dystroglycan. Am J Hum Genet. 2013 Feb 26. doi:pii: S0002-9297(13)00069-4. 10.1016/j.ajhg.2013.01.016. [Epub ahead of print].

Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning

Authors:
Steventon B, Mayor R, Streit A
Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.04.025
Epub:
Not Epub
Abstract:
In the vertebrate head, central and peripheral components of the sensory nervous system have different embryonic origins, the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Steventon B, Mayor R, Streit A. Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.04.025.

Netrin/DCC signaling controls contralateral dendrites of octavolateralis efferent neurons

Authors:
Suli A, Mortimer N, Shepherd I, Chien CB
Citation:
J Neurosci. 2006 Dec 20;26(51):13328-37
Epub:
Not Epub
Abstract:
The guidance molecule Netrin and its receptor DCC (deleted in colorectal cancer) attract commissural axons toward the midline...
Organism or Cell Type:
zebrafish
Citation Extract:
Suli A, Mortimer N, Shepherd I, Chien CB. Netrin/DCC signaling controls contralateral dendrites of octavolateralis efferent neurons. J Neurosci. 2006 Dec 20;26(51):13328-37.

Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention

Authors:
Strizzi L, Postovit LM, Margaryan NV, Lipavsky A, Gadiot J, Blank C, Seftor RE, Seftor EA, Hendrix MJ
Citation:
Expert Rev Dermatol. 2009;4(1):67-78
Epub:
Not Epub
Abstract:
Nodal, an embryonic morphogen belonging to the TGF-beta superfamily, is an important regulator of embryonic stem cell fate. We...
Organism or Cell Type:
cell culture: human C8161 melanoma cells
Citation Extract:
Strizzi L, Postovit LM, Margaryan NV, Lipavsky A, Gadiot J, Blank C, Seftor RE, Seftor EA, Hendrix MJ. Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention. Expert Rev Dermatol. 2009;4(1):67-78.

Nucleic acid-based inhibition of flavivirus infections

Authors:
Stein DA, Shi PY
Citation:
Front Biosci. 2008 Jan 1;13:1385-95
Epub:
Not Epub
Abstract:
The genus Flavivirus in the family Flaviviridae consists of many arthropod-transmitted human pathogens, including dengue,...
Citation Extract:
Stein DA, Shi PY. Nucleic acid-based inhibition of flavivirus infections. Front Biosci. 2008 Jan 1;13:1385-95.

Oligonucleotide antiviral therapeutics: Antisense and RNA interference for highly pathogenic RNA viruses

Authors:
Spurgers KB, Sharkey CM, Warfield KL, Bavari S
Citation:
Antiviral Res. 2008 Apr;78(1):26-36. Epub 2008 Jan 14.
Epub:
Not Epub
Abstract:
RNA viruses are a significant source of morbidity and mortality in humans every year. Additionally, the potential use of these...
Organism or Cell Type:
Various viruses
Citation Extract:
Spurgers KB, Sharkey CM, Warfield KL, Bavari S. Oligonucleotide antiviral therapeutics: Antisense and RNA interference for highly pathogenic RNA viruses. Antiviral Res. 2008 Apr;78(1):26-36. Epub 2008 Jan 14..

Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation

Authors:
Sun SC, Wei L, Li M, Lin SL, Xu BZ, Liang XW, Kim NH, Schatten H, Lu SS, Sun QY
Citation:
Cell Cycle. 2009 Oct 19;8(20). [Epub ahead of print]
Epub:
Not Epub
Abstract:
Survivin is a member of inhibitors of apoptosis proteins (IAPs), which have multiple regulatory functions in mitosis, but its...
Organism or Cell Type:
mouse oocytes
Citation Extract:
Sun SC, Wei L, Li M, Lin SL, Xu BZ, Liang XW, Kim NH, Schatten H, Lu SS, Sun QY. Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation. Cell Cycle. 2009 Oct 19;8(20). [Epub ahead of print].

Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis

Authors:
Stewart RA, Sanda T, Widlund HR, Zhu S, Swanson KD, Hurley AD, Bentires-Alj M, Fisher DE, Kontaridis MI, Look AT, Neel BG
Citation:
Dev Cell. 2010 May 18;18(5):750-62
Epub:
Not Epub
Abstract:
The tyrosine phosphatase SHP2 (PTPN11) regulates cellular proliferation, survival, migration, and differentiation during...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stewart RA, Sanda T, Widlund HR, Zhu S, Swanson KD, Hurley AD, Bentires-Alj M, Fisher DE, Kontaridis MI, Look AT, Neel BG. Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis. Dev Cell. 2010 May 18;18(5):750-62.

Physiological and Molecular Characterization of Connexin Hemichannels in Zebrafish Retinal Horizontal Cells

Authors:
Sun Z, Risner ML, van Asselt JB, Zhang DQ, Kamermans M, McMahon DG
Citation:
J Neurophysiol. 2012 Feb 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Connexin channels mediate electrical synaptic transmission when assembled as cell-to-cell pores at gap junctions and can...
Delivery Method:
Injection then electroporation in vivo
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Z, Risner ML, van Asselt JB, Zhang DQ, Kamermans M, McMahon DG. Physiological and Molecular Characterization of Connexin Hemichannels in Zebrafish Retinal Horizontal Cells. J Neurophysiol. 2012 Feb 22. [Epub ahead of print].

Plasticity of photoreceptor-generating retinal progenitors revealed by prolonged retinoic acid exposure

Authors:
Stevens CB, Cameron DA, Stenkamp DL
Citation:
BMC Dev Biol. 2011;11:51 doi:10.1186/1471-213X-11-51
Epub:
Not Epub
Abstract:
BACKGROUND Retinoic acid (RA) is important for vertebrate eye morphogenesis and is a regulator of photoreceptor development in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stevens CB, Cameron DA, Stenkamp DL. Plasticity of photoreceptor-generating retinal progenitors revealed by prolonged retinoic acid exposure. BMC Dev Biol. 2011;11:51 doi:10.1186/1471-213X-11-51.

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