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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Modulation of 5-HT3 receptor distribution by the light chain of MAP1B expressed in HEK 293 cells

Authors:
Sun H, Hu X, Emerit MB, Schoenebeck JC, Kimmel CE, Peoples RW, Miko A, Zhang L
Citation:
J Physiol. 2007 Dec 6; [Epub ahead of print]
Epub:
Not Epub
Abstract:
Regulation of ligand-gated ion channel (LGIC) function and trafficking by cytoskeleton proteins has been the topic of recent...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: HEK 293
Citation Extract:
Sun H, Hu X, Emerit MB, Schoenebeck JC, Kimmel CE, Peoples RW, Miko A, Zhang L. Modulation of 5-HT3 receptor distribution by the light chain of MAP1B expressed in HEK 293 cells. J Physiol. 2007 Dec 6; [Epub ahead of print].

Morpholino and Phosphorothioate Antisense Oligomers Compared in Cell-Free and In-Cell Systems

Authors:
Summerton J, Stein D, Huang SB, Matthews P, Weller D, Partridge M
Citation:
Antisense & Nucleic Acid Drug Development 1997 7: 63-70
Epub:
Not Epub
Abstract:
Morpholino and phosphorothioate (S-DNA) antisense oligos were compared in both cell-free and in-cell translation systems. In...
Delivery Method:
in vitro: TNT and scrape loading
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Summerton J, Stein D, Huang SB, Matthews P, Weller D, Partridge M. Morpholino and Phosphorothioate Antisense Oligomers Compared in Cell-Free and In-Cell Systems. Antisense & Nucleic Acid Drug Development 1997 7: 63-70.

Morpholino Antisense Oligomers: The Case for an RNase-H Independent Structural Type

Authors:
Summerton J
Citation:
Biochimica et Biophysica Acta 1999 1489: 141-158
Epub:
Not Epub
Abstract:
RNase H-competent phosphorothioates (S-DNAs) have dominated the antisense field in large part because they offer reasonable...
Citation Extract:
Summerton J. Morpholino Antisense Oligomers: The Case for an RNase-H Independent Structural Type. Biochimica et Biophysica Acta 1999 1489: 141-158.

Morpholino Antisense Oligos: Applications in Biopharmaceutical Research

Authors:
Summerton J
Citation:
Innovations in Pharmaceutical Technology. Sept 2005
Epub:
Not Epub
Abstract:
Oligos which bind to complementary RNA sequences are commonly called ‘antisense’ oligos because they are typically used to...
Citation Extract:
Summerton J. Morpholino Antisense Oligos: Applications in Biopharmaceutical Research. Innovations in Pharmaceutical Technology. Sept 2005.

Morpholino phosphorodiamidate oligonucleotides in zebrafish: A recipe for functional genomics?

Authors:
Sumanas S, Larson JD
Citation:
Briefings in Functional Genomics and Proteomics. 2002. 1(3):239-256
Epub:
Not Epub
Abstract:
Morpholino phosphorodiamidate anti-sense oligonucleotides (MPOs) have recently emerged as a tool for gene-specific knockdown....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sumanas S, Larson JD. Morpholino phosphorodiamidate oligonucleotides in zebrafish: A recipe for functional genomics?. Briefings in Functional Genomics and Proteomics. 2002. 1(3):239-256.

Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity

Authors:
Summerton J
Citation:
Med Chem. 2007;7(7):651-660
Epub:
Not Epub
Abstract:
Generally a gene knockdown agent should achieve high sequence specificity and should lack off-target effects (non-antisense...
Citation Extract:
Summerton J. Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity. Med Chem. 2007;7(7):651-660.

Morpholinos and PNAs compared

Authors:
Summerton J
Citation:
Letters in Peptide Science 2004 10: 215-236
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
various
Organism or Cell Type:
not applicable
Citation Extract:
Summerton J. Morpholinos and PNAs compared. Letters in Peptide Science 2004 10: 215-236.

Morpholinos and PNAs Compared In: Peptide Nucleic Acids, Morpholinos, and Related Antisense Biomolecules

Authors:
Summerton J
Citation:
Janson C. and During M., eds. Landes Biosciences 2004, Georgetown, TX.
Epub:
Not Epub
Citation Extract:
Summerton J. Morpholinos and PNAs Compared In: Peptide Nucleic Acids, Morpholinos, and Related Antisense Biomolecules. Janson C. and During M., eds. Landes Biosciences 2004, Georgetown, TX..

Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation

Authors:
Stubbs JL, Vladar EK, Axelrod JD, Kintner C
Citation:
Nat Cell Biol. 2012 Jan 8;14(2):140-7. doi: 10.1038/ncb2406
Epub:
Not Epub
Abstract:
Multiciliate cells function prominently in the respiratory system, brain ependyma and female reproductive tract to produce...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Stubbs JL, Vladar EK, Axelrod JD, Kintner C. Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation. Nat Cell Biol. 2012 Jan 8;14(2):140-7. doi: 10.1038/ncb2406.

Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells.

Authors:
Starr CJ, Kappler JA, Chan DK, Kollmar R, Hudspeth AJ
Citation:
Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2572-7
Epub:
Not Epub
Abstract:
To identify genes important for hair-cell function, we conducted a mutagenic screen in zebrafish. Larvae from one mutant line,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Starr CJ, Kappler JA, Chan DK, Kollmar R, Hudspeth AJ. Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells.. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2572-7.

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