You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Differentiation-dependent antiviral capacities of amphibian (Xenopus laevis) macrophages

Authors:
Yaparla A, Popovic M, Grayfer L
Citation:
J Biol Chem. 2018 Feb 2;293(5):1736-1744. doi: 10.1074/jbc.M117.794065. Epub 2017 Dec 19. PMID: 29259133; PMCID: PMC5798303
Epub:
Yes
Abstract:
Infections by ranaviruses such as Frog virus 3 (Fv3) are significantly contributing to the worldwide amphibian population...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC5798303/
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
cell culture: Xenopus laevis kidney (A6) cell line
Citation Extract:
Yaparla A, Popovic M, Grayfer L. Differentiation-dependent antiviral capacities of amphibian (Xenopus laevis) macrophages. J Biol Chem. 2018 Feb 2;293(5):1736-1744. doi: 10.1074/jbc.M117.794065. Epub 2017 Dec 19. PMID: 29259133; PMCID: PMC5798303.

A novel gene's role in an ancient mechanism: secreted Frizzled-related protein 1 is a critical component in the anterior-posterior Wnt signaling network that governs the establishment of the anterior neuroectoderm in sea urchin embryos

Authors:
Khadka A, Martínez-Bartolomé M, Burr SD, Range RC
Citation:
Evodevo. 2018 Jan 22;9:1. doi: 10.1186/s13227-017-0089-3. eCollection 2018
Epub:
Not Epub
Abstract:
The anterior neuroectoderm (ANE) in many deuterostome embryos (echinoderms, hemichordates, urochordates, cephalochordates, and...
Link:
https://evodevojournal.biomedcentral.com/articles/10.1186/s13227-017-0089-3
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Khadka A, Martínez-Bartolomé M, Burr SD, Range RC. A novel gene's role in an ancient mechanism: secreted Frizzled-related protein 1 is a critical component in the anterior-posterior Wnt signaling network that governs the establishment of the anterior neuroectoderm in sea urchin embryos. Evodevo. 2018 Jan 22;9:1. doi: 10.1186/s13227-017-0089-3. eCollection 2018.

Structure/Function Studies of the α4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses

Authors:
Leacock S, Syed P, James VM, Bode A, Kawakami K, Keramidas A, Suster M, Lynch JW, Harvey RJ
Citation:
Front Mol Neurosci. 2018;(11). doi:10.3389/fnmol.2018.00023
Epub:
Not Epub
Abstract:
Inhibitory glycine receptors (GlyRs) are pentameric ligand-gated anion channels with major roles in startle disease/...
Link:
https://www.frontiersin.org/articles/10.3389/fnmol.2018.00023/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leacock S, Syed P, James VM, Bode A, Kawakami K, Keramidas A, Suster M, Lynch JW, Harvey RJ. Structure/Function Studies of the α4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses. Front Mol Neurosci. 2018;(11). doi:10.3389/fnmol.2018.00023.

A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis

Authors:
Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen J-N, Dupuy AJ, Iruela-Arispe ML
Citation:
Cell Rep. 2018;22(5):1211-24. doi:10.1016/j.celrep.2018.01.017
Epub:
Not Epub
Abstract:
Given its role as the source of definitive hematopoietic cells, we sought to determine whether mutations initiated in the...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30034-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen J-N, Dupuy AJ, Iruela-Arispe ML. A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis. Cell Rep. 2018;22(5):1211-24. doi:10.1016/j.celrep.2018.01.017.

Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function

Authors:
Mendoza-Ferreira N, Coutelier M, Janzen E, Hosseinibarkooie S, Löhr H, Schneider S, Milbradt J, Karakaya M, Riessland M, Pichlo C, Torres-Benito L, Singleton A, Zuchner S, Brice A, Durr A, Hammerschmidt M, Stevanin G, Wirth B
Citation:
Neurol Genet. 2018 Jan 19;4(1):e209. doi: 10.1212/NXG.0000000000000209. eCollection 2018 Feb
Epub:
Not Epub
Abstract:
Objective: To ascertain the genetic and functional basis of complex autosomal recessive cerebellar ataxia (ARCA) presented by 2...
Link:
http://ng.neurology.org/content/4/1/e209
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mendoza-Ferreira N, Coutelier M, Janzen E, Hosseinibarkooie S, Löhr H, Schneider S, Milbradt J, Karakaya M, Riessland M, Pichlo C, Torres-Benito L, Singleton A, Zuchner S, Brice A, Durr A, Hammerschmidt M, Stevanin G, Wirth B. Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function. Neurol Genet. 2018 Jan 19;4(1):e209. doi: 10.1212/NXG.0000000000000209. eCollection 2018 Feb.

The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression

Authors:
Yu SH, Zhu KY, Zhang F, Wang J, Yuan H, Chen Y, Jin Y, Dong M, Wang L, Jia XE, Gao L, Dong ZW, Ren CG, Chen LT, Huang QH, Deng M, Zon LI, Zhou Y, Zhu J, Xu PF, Liu TX
Citation:
Biochim Biophys Acta. 2018 Jan 26. pii: S1874-9399(17)30309-7. doi: 10.1016/j.bbagrm.2017.12.009. [Epub ahead of print]
Epub:
Yes
Abstract:
The histone demethylase Jmjd3 plays a critical role in in cell lineage specification and differentiation at various stages of...
Link:
https://www.ncbi.nlm.nih.gov/pubmed/29378332
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu SH, Zhu KY, Zhang F, Wang J, Yuan H, Chen Y, Jin Y, Dong M, Wang L, Jia XE, Gao L, Dong ZW, Ren CG, Chen LT, Huang QH, Deng M, Zon LI, Zhou Y, Zhu J, Xu PF, Liu TX. The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. Biochim Biophys Acta. 2018 Jan 26. pii: S1874-9399(17)30309-7. doi: 10.1016/j.bbagrm.2017.12.009. [Epub ahead of print].

The pivotal role of aristaless in development and evolution of diverse antennal morphologies in moths and butterflies

Authors:
Ando T, Fujiwara H, Kojima T
Citation:
BMC Evol Biol. 2018 Jan 25;18(1):8. doi: 10.1186/s12862-018-1124-2
Epub:
Not Epub
Abstract:
BACKGROUND: Antennae are multi-segmented appendages and main odor-sensing organs in insects. In Lepidoptera (moths and...
Link:
https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-018-1124-2
Delivery Method:
electroporation
Organism or Cell Type:
Bombyx mori (silk moth)
Citation Extract:
Ando T, Fujiwara H, Kojima T. The pivotal role of aristaless in development and evolution of diverse antennal morphologies in moths and butterflies. BMC Evol Biol. 2018 Jan 25;18(1):8. doi: 10.1186/s12862-018-1124-2.

A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target

Authors:
Ibhazehiebo K, Gavrilovici C, de la Hoz CL, Ma S-C, Rehak R, Kaushik G, Meza Santoscoy PL, Scott L, Nath N, Kim D-Y, Rho JM, Kurrasch DM
Citation:
Brain 2018;awx364. doi:10.1093/brain/awx364
Epub:
Not Epub
Abstract:
Despite the development of newer anti-seizure medications over the past 50 years, 30-40% of patients with epilepsy remain...
Link:
https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awx364/4823617
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ibhazehiebo K, Gavrilovici C, de la Hoz CL, Ma S-C, Rehak R, Kaushik G, Meza Santoscoy PL, Scott L, Nath N, Kim D-Y, Rho JM, Kurrasch DM. A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target. Brain 2018;awx364. doi:10.1093/brain/awx364.

Nodal induces sequential restriction of germ cell factors during primordial germ cell specification

Authors:
Fresques TM, Wessel GM
Citation:
Development. 2018;145(2):dev155663. doi:10.1242/dev.155663
Epub:
Not Epub
Abstract:
Specification of the germ cell lineage is required for sexual reproduction in animals. The mechanism of germ cell specification...
Link:
http://dev.biologists.org/content/145/2/dev155663
Delivery Method:
microinjection
Organism or Cell Type:
sea star
Citation Extract:
Fresques TM, Wessel GM. Nodal induces sequential restriction of germ cell factors during primordial germ cell specification. Development. 2018;145(2):dev155663. doi:10.1242/dev.155663.

Compound heterozygous loss-of-function mutations in KIF20A are associated with a novel lethal congenital cardiomyopathy in two siblings

Authors:
Louw JJ, Nunes Bastos R, Chen X, Verdood C, Corveleyn A, Jia Y, Breckpot J, Gewillig M, Peeters H, Santoro MM, Barr F, Devriendt K
Citation:
PLoS Genet. 2018 Jan 22;14(1):e1007138. doi: 10.1371/journal.pgen.1007138. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Congenital or neonatal cardiomyopathies are commonly associated with a poor prognosis and have multiple etiologies. In two...
Link:
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007138
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Louw JJ, Nunes Bastos R, Chen X, Verdood C, Corveleyn A, Jia Y, Breckpot J, Gewillig M, Peeters H, Santoro MM, Barr F, Devriendt K. Compound heterozygous loss-of-function mutations in KIF20A are associated with a novel lethal congenital cardiomyopathy in two siblings. PLoS Genet. 2018 Jan 22;14(1):e1007138. doi: 10.1371/journal.pgen.1007138. [Epub ahead of print].

Pages