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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Monitoring dissociation kinetics during electrophoretic focusing enables high-specificity nucleic acid detection

Authors:
Zeidman Kalman T, Khalandovsky R, Tenenbaum Gonikman E, Bercovici M
Citation:
Angew Chem. 2018;[Epub ahead of print] doi:10.1002/ange.201711673
Epub:
Yes
Abstract:
A wide range of medical conditions can be diagnosed through sequence-specific analysis of nucleic acids. However, a major...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/ange.201711673/abstract
Citation Extract:
Zeidman Kalman T, Khalandovsky R, Tenenbaum Gonikman E, Bercovici M. Monitoring dissociation kinetics during electrophoretic focusing enables high-specificity nucleic acid detection. Angew Chem. 2018;[Epub ahead of print] doi:10.1002/ange.201711673.

Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish

Authors:
Gerri C, Marass M, Rossi A, Stainier DYR
Citation:
Blood. 2018 Jan 16. pii: blood-2017-07-797795. doi: 10.1182/blood-2017-07-797795. [Epub ahead of print]
Epub:
Yes
Abstract:
During development, hematopoietic stem cells (HSCs) derive from specialized endothelial cells (ECs), called hemogenic...
Link:
http://www.bloodjournal.org/content/early/2018/01/16/blood-2017-07-797795.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gerri C, Marass M, Rossi A, Stainier DYR. Hif-1α and Hif-2α regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish. Blood. 2018 Jan 16. pii: blood-2017-07-797795. doi: 10.1182/blood-2017-07-797795. [Epub ahead of print].

Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish

Authors:
Liu Z-Z, Wang Z-L, Choi T-I, Huang W-T, Wang H-T, Han Y-Y, Zhu L-Y, Kim H-T, Choi J-H, Lee J-S, Kim H-G, Zhao J, Chen Y, Lu Z, Tian X-L, Pan B-X, Li B-M, Kim C-H
Citation:
Am J. Pathol. 2018;[Epub ahead of print] doi:10.1016/j.ajpath.2017.12.005
Epub:
Yes
Abstract:
CHARGE syndrome is a congenital disorder affecting multiple organs and mainly caused by mutations in CHD7, a gene encoding a...
Link:
http://ajp.amjpathol.org/article/S0002-9440(17)30669-7/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Z-Z, Wang Z-L, Choi T-I, Huang W-T, Wang H-T, Han Y-Y, Zhu L-Y, Kim H-T, Choi J-H, Lee J-S, Kim H-G, Zhao J, Chen Y, Lu Z, Tian X-L, Pan B-X, Li B-M, Kim C-H. Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish. Am J. Pathol. 2018;[Epub ahead of print] doi:10.1016/j.ajpath.2017.12.005.

Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia

Authors:
Jiang X, Wooderchak-Donahue WL, McDonald J, Ghatpande P, Baalbaki M, Sandoval M, Hart D, Clay H, Coughlin S, Lagna G, Bayrak-Toydemir P, Hata A
Citation:
Sci Signal. 2018;11(513):eaan6831. doi:10.1126/scisignal.aan6831
Epub:
Not Epub
Abstract:
The transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) family of cytokines critically regulates vascular...
Link:
http://stke.sciencemag.org/content/11/513/eaan6831.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang X, Wooderchak-Donahue WL, McDonald J, Ghatpande P, Baalbaki M, Sandoval M, Hart D, Clay H, Coughlin S, Lagna G, Bayrak-Toydemir P, Hata A. Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia. Sci Signal. 2018;11(513):eaan6831. doi:10.1126/scisignal.aan6831.

Microinjection of Antisense Morpholinos, CRISPR/Cas9 RNP, and RNA/DNA into Zebrafish Embryos

Authors:
Xin Y, Duan C
Citation:
Methods Mol Biol. 2018;1742:205-211. doi: 10.1007/978-1-4939-7665-2_18
Epub:
Not Epub
Abstract:
In this chapter, we describe a stepwise protocol of microinjection. Using this method, antisense morpholinos, CRISPR-Cas9...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-7665-2_18
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xin Y, Duan C. Microinjection of Antisense Morpholinos, CRISPR/Cas9 RNP, and RNA/DNA into Zebrafish Embryos. Methods Mol Biol. 2018;1742:205-211. doi: 10.1007/978-1-4939-7665-2_18.

Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response

Authors:
Paone C, Rudeck S, Etard C, Strähle U, Rottbauer W, Just S
Citation:
Biochem Biophys Res Commun. 2018 Jan 10. pii: S0006-291X(18)30066-4. doi: 10.1016/j.bbrc.2018.01.060. [Epub ahead of print]
Epub:
Yes
Abstract:
Sarcomeric protein turnover needs to be tightly balanced to assure proper assembly and renewal of sarcomeric units within...
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X18300664
Citation Extract:
Paone C, Rudeck S, Etard C, Strähle U, Rottbauer W, Just S. Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response. Biochem Biophys Res Commun. 2018 Jan 10. pii: S0006-291X(18)30066-4. doi: 10.1016/j.bbrc.2018.01.060. [Epub ahead of print].

Transient Disruption of Adenosine Signaling During Embryogenesis Triggers a Pro-epileptic Phenotype in Adult Zebrafish

Authors:
Menezes FP, Machado Torresini F, Nery LR, da Silva RS
Citation:
Mol Neurobiol. 2018 Jan 11. doi: 10.1007/s12035-017-0850-6. [Epub ahead of print]
Epub:
Yes
Abstract:
Adenosinergic signaling has important effects on brain function, anatomy, and physiology in both late and early stages of...
Link:
https://link.springer.com/article/10.1007%2Fs12035-017-0850-6
Organism or Cell Type:
zebrafish
Citation Extract:
Menezes FP, Machado Torresini F, Nery LR, da Silva RS. Transient Disruption of Adenosine Signaling During Embryogenesis Triggers a Pro-epileptic Phenotype in Adult Zebrafish. Mol Neurobiol. 2018 Jan 11. doi: 10.1007/s12035-017-0850-6. [Epub ahead of print].

Use of Larval Zebrafish Model to Study Within-Host Infection Dynamics

Authors:
Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ
Citation:
Methods Mol Biol. 2018;1736:147-156. doi: 10.1007/978-1-4939-7638-6_14
Epub:
Not Epub
Abstract:
Investigating bacterial dynamics within the infected host has proved very useful for understanding mechanisms of pathogenesis....
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-7638-6_14
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prajsnar TK, McVicker G, Williams A, Renshaw SA, Foster SJ. Use of Larval Zebrafish Model to Study Within-Host Infection Dynamics. Methods Mol Biol. 2018;1736:147-156. doi: 10.1007/978-1-4939-7638-6_14.

Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis

Authors:
Wu Y-H, Lee YH, Shih HY, Chen SH, Cheng YC, Chiu DT-Y
Citation:
Cell Death Dis. 2018;9:10. doi:10.1038/s41419-017-0005-8
Epub:
Not Epub
Abstract:
Glucose-6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme involved in the pentose phosphate shunt for producing...
Link:
https://www.nature.com/articles/s41419-017-0005-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y-H, Lee YH, Shih HY, Chen SH, Cheng YC, Chiu DT-Y. Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis. Cell Death Dis. 2018;9:10. doi:10.1038/s41419-017-0005-8.

Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis

Authors:
Wu Y-H, Lee YH, Shih HY, Chen SH, Cheng YC, Chiu DT-Y
Citation:
Cell Death Dis. 2018;9:10. doi:10.1038/s41419-017-0005-8
Epub:
Not Epub
Abstract:
Glucose-6-phosphate dehydrogenase (G6PD) is a housekeeping enzyme involved in the pentose phosphate shunt for producing...
Link:
https://www.nature.com/articles/s41419-017-0005-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y-H, Lee YH, Shih HY, Chen SH, Cheng YC, Chiu DT-Y. Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis. Cell Death Dis. 2018;9:10. doi:10.1038/s41419-017-0005-8.

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