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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Cold-inducible RNA binding protein (CIRP), a novel XTcf-3 specific target gene regulates neural development in Xenopus

Authors:
van Venrooy S, Fichtner D, Kunz M, Wedlich D, Gradl D
Citation:
BMC Dev Biol. 2008 Aug 7;8:77.
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: As nuclear mediators of wnt/beta-catenin signaling, Lef/Tcf transcription factors play important roles in...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
van Venrooy S, Fichtner D, Kunz M, Wedlich D, Gradl D. Cold-inducible RNA binding protein (CIRP), a novel XTcf-3 specific target gene regulates neural development in Xenopus. BMC Dev Biol. 2008 Aug 7;8:77..

Collective cell migration drives morphogenesis of the kidney nephron

Authors:
Vasilyev A, Liu Y, Mudumana S, Mangos S, Lam PY, Majumdar A, Zhao J, Poon KL, Kondrychyn I, Korzh V, Drummond IA
Citation:
PLoS Biol. 2009 Jan 6;7(1):e9
Epub:
Not Epub
Abstract:
Tissue organization in epithelial organs is achieved during development by the combined processes of cell differentiation and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vasilyev A, Liu Y, Mudumana S, Mangos S, Lam PY, Majumdar A, Zhao J, Poon KL, Kondrychyn I, Korzh V, Drummond IA. Collective cell migration drives morphogenesis of the kidney nephron. PLoS Biol. 2009 Jan 6;7(1):e9.

Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution

Authors:
van den Akker WM, Brox A, Puelles L, Durston AJ, Medina L
Citation:
J Comp Neurol. 2007 Nov 19;506(2):211-223 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Knockout of the Nkx2.1 (Titf-1) homeobox gene in the mouse leads to severe malformation and size reduction of the basal...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
van den Akker WM, Brox A, Puelles L, Durston AJ, Medina L. Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution. J Comp Neurol. 2007 Nov 19;506(2):211-223 [Epub ahead of print].

Connexin-Specific Cell to Cell Transfer of Short Interfering RNA by Gap Junctions

Authors:
Valiunas V, Polosina YY, Miller H, Potapova IA, Valiuniene L, Doronin S, Mathias RT, Robinson RB, Rosen MR, Cohen IS, Brink PR
Citation:
J Physiol. 2005 Oct 15;568(Pt 2):459-68. Epub 2005 Jul 21
Epub:
Not Epub
Abstract:
The purpose of this study was to determine whether oligonucleotides the size of siRNA are permeable to gap junctions and...
Delivery Method:
Dual whole cell patch clamp
Organism or Cell Type:
Cell Culture: mouse embryonic fibroblast line Mβ16 and Hela Cell
Citation Extract:
Valiunas V, Polosina YY, Miller H, Potapova IA, Valiuniene L, Doronin S, Mathias RT, Robinson RB, Rosen MR, Cohen IS, Brink PR. Connexin-Specific Cell to Cell Transfer of Short Interfering RNA by Gap Junctions. J Physiol. 2005 Oct 15;568(Pt 2):459-68. Epub 2005 Jul 21.

Control of local Rho GTPase crosstalk by Abr

Authors:
Vaughan EM, Miller AL, Yu HY, Bement WM
Citation:
Curr Biol. 2011 Feb 22;21(4):270-7. Epub 2011 Feb 3. Erratum in: Curr Biol. 2011 Apr 12;21(7):623
Epub:
Not Epub
Abstract:
BACKGROUND: The Rho GTPases-Rho, Rac, and Cdc42-regulate the dynamics of F-actin (filamentous actin) and myosin-2 with...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vaughan EM, Miller AL, Yu HY, Bement WM. Control of local Rho GTPase crosstalk by Abr. Curr Biol. 2011 Feb 22;21(4):270-7. Epub 2011 Feb 3. Erratum in: Curr Biol. 2011 Apr 12;21(7):623.

Correct anteroposterior patterning of the zebrafish neurectoderm in the absence of the early dorsal organizer

Authors:
Varga M, Maegawa S, Weinberg ES
Citation:
BMC Dev Biol. 2011 May 16;11(1):26. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: The embryonic organizer (i.e., Spemann organizer) has a pivotal role in the establishment of the dorsoventral (DV)...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Varga M, Maegawa S, Weinberg ES. Correct anteroposterior patterning of the zebrafish neurectoderm in the absence of the early dorsal organizer. BMC Dev Biol. 2011 May 16;11(1):26. [Epub ahead of print].

Developmental defects and neuromuscular alterations due to mitofusin 2 gene (MFN2) silencing in zebrafish: a new model for Charcot-Marie-Tooth type 2A neuropathy

Authors:
Vettori A, Bergamin G, Moro E, Vazza G, Polo G, Tiso N, Argenton F, Mostacciuolo ML
Citation:
Neuromusc Disord. 2011 Jan;21(1):58-67. doi: 10.1016/j.nmd.2010.09.002. Epub 2010 Oct 14
Epub:
Not Epub
Abstract:
The development of new animal models is a crucial step in determining the pathological mechanism underlying neurodegenerative...
Organism or Cell Type:
zebrafish
Citation Extract:
Vettori A, Bergamin G, Moro E, Vazza G, Polo G, Tiso N, Argenton F, Mostacciuolo ML. Developmental defects and neuromuscular alterations due to mitofusin 2 gene (MFN2) silencing in zebrafish: a new model for Charcot-Marie-Tooth type 2A neuropathy. Neuromusc Disord. 2011 Jan;21(1):58-67. doi: 10.1016/j.nmd.2010.09.002. Epub 2010 Oct 14.

Differentiation of zebrafish melanophores depends on transcription factors AP2 alpha and AP2 epsilon

Authors:
Van Otterloo E, Li W, Bonde G, Day KM, Hsu MY, Cornell RA
Citation:
PLoS Genet. 2010 Sep 16;6(9). pii: e1001122
Epub:
Not Epub
Abstract:
A model of the gene-regulatory-network (GRN), governing growth, survival, and differentiation of melanocytes, has emerged from...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Otterloo E, Li W, Bonde G, Day KM, Hsu MY, Cornell RA. Differentiation of zebrafish melanophores depends on transcription factors AP2 alpha and AP2 epsilon. PLoS Genet. 2010 Sep 16;6(9). pii: e1001122.

Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis

Authors:
Van Stry M, Kazlauskas A, Schreiber SL, Symes K
Citation:
Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8233-8. Epub 2005 May 26
Epub:
Not Epub
Abstract:
Platelet-derived growth factor receptor (PDGFR) signaling is essential for normal embryonic development in many organisms,...
Organism or Cell Type:
Xenopus
Citation Extract:
Van Stry M, Kazlauskas A, Schreiber SL, Symes K. Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8233-8. Epub 2005 May 26.

Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity

Authors:
van Boxtel AL, Kamstra JH, Fluitsma DM, Legler J
Citation:
Toxicol Appl Pharmacol. 2009 Dec 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Dithiocarbamates (DTCs) are a class of compounds that are extensively used in agriculture as pesticides. As such humans and...
Organism or Cell Type:
zebrafish
Citation Extract:
van Boxtel AL, Kamstra JH, Fluitsma DM, Legler J. Dithiocarbamates are teratogenic to developing zebrafish through inhibition of lysyl oxidase activity. Toxicol Appl Pharmacol. 2009 Dec 29. [Epub ahead of print].

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