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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Gene-Specific Ebola Therapies Protect Nonhuman Primates from Lethal Diseases
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Citation:
Chem-Bio Defense Quarterly. 2006 3(2):8-9 Epub:
Not Epub Abstract:
First paragraph: It was February 11, 2004, and the female scientist was working in a Bio-Safety Level 4 maximum containment... Citation Extract: Vander-Linden CL. Gene-Specific Ebola Therapies Protect Nonhuman Primates from Lethal Diseases. Chem-Bio Defense Quarterly. 2006 3(2):8-9. |
Genome-Wide RNA Interference in Drosophila Cells Identifies G Protein-Coupled Receptor Kinase 2 as a Conserved Regulator of NF-kappaB Signaling
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Citation:
2010 Jun 1;184(11):6188-98. doi: 10.4049/jimmunol.1000261. Epub 2010 Apr 26. Epub:
Not Epub Abstract:
Because NF-kappaB signaling pathways are highly conserved in evolution, the fruit fly Drosophila melanogaster provides a good... Organism or Cell Type:
zebrafish Citation Extract: Valanne S, Myllymäki H, Kallio J, Schmid MR, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani SS, Engström Y, Silvennoinen O, Hultmark D, Parikka M, Rämet M. Genome-Wide RNA Interference in Drosophila Cells Identifies G Protein-Coupled Receptor Kinase 2 as a Conserved Regulator of NF-kappaB Signaling. 2010 Jun 1;184(11):6188-98. doi: 10.4049/jimmunol.1000261. Epub 2010 Apr 26.. |
Gli function is essential for motor neuron induction in zebrafish
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Citation:
Dev Biol. 2005 Jun 15;282(2):550-70. Epub:
Not Epub Abstract:
The Gli family of zinc-finger transcription factors mediates Hedgehog (Hh) signaling in all vertebrates. However, their roles... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Vanderlaan G, Tyurina OV, Karlstrom RO, Chandrasekhar A. Gli function is essential for motor neuron induction in zebrafish. Dev Biol. 2005 Jun 15;282(2):550-70.. |
HELLP babies link a novel lincRNA to the trophoblast cell cycle
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Citation:
J Clin Invest. 2012;[Epub ahead of print] doi:10.1172/JCI65171 Epub:
Not Epub Abstract:
The HELLP syndrome is a pregnancy-associated disease inducing hemolysis, elevated liver enzymes, and low platelets in the... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: SGHPL-5 Citation Extract: van Dijk M, Thulluru HK, Mulders J, Michel OJ, Poutsma A, Windhorst S, Kleiverda G, Sie D, Lachmeijer AMA, Oudejans CBM. HELLP babies link a novel lincRNA to the trophoblast cell cycle. J Clin Invest. 2012;[Epub ahead of print] doi:10.1172/JCI65171. |
Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis
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Citation:
Dev Biol. 2012 Sep 8. pii: S0012-1606(12)00491-5. doi: 10.1016/j.ydbio.2012.08.032. [Epub ahead of print] Epub:
Not Epub Abstract:
During vertebrate retinogenesis, the precise balance between retinoblast proliferation and differentiation is spatially and... Organism or Cell Type:
zebrafish Citation Extract: Uribe RA, Kwon T, Marcotte EM, Gross JM. Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis. Dev Biol. 2012 Sep 8. pii: S0012-1606(12)00491-5. doi: 10.1016/j.ydbio.2012.08.032. [Epub ahead of print]. |
Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics
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Citation:
Development. 2010 Nov;137(22):3763-74. Epub 2010 Oct 13 Epub:
Not Epub Abstract:
Inhibitor of differentiation (Id) family helix-loop-helix proteins regulate the proliferation, survival and differentiation of... Organism or Cell Type:
zebrafish Citation Extract: Uribe RA, Gross JM. Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics. Development. 2010 Nov;137(22):3763-74. Epub 2010 Oct 13. |
IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production
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Citation:
J Immunol. 2006 Jun 15;176(12):7768-74 Epub:
Not Epub Abstract:
IL-23 is a heterodimeric cytokine comprising a p19 subunit associated with the IL-12/23p40 subunit. Like IL-12, IL-23 is... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: primary human monocyte-derived dendritic cells Citation Extract: Vaknin-Dembinsky A, Balashov K, Weiner HL. IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol. 2006 Jun 15;176(12):7768-74. |
Importance of the pluripotency factor LIN28 in the mammalian nucleolus during early embryonic development
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Citation:
Development. 2012 Dec;139(24):4514-23. doi: 10.1242/dev.083279 Epub:
Not Epub Abstract:
The maternal nucleolus is required for proper activation of the embryonic genome (EGA) and early embryonic development.... Delivery Method:
Microinjection Organism or Cell Type:
mouse embryos,preimplantation Citation Extract: Vogt EJ, Meglicki M, Hartung KI, Borsuk E, Behr R. Importance of the pluripotency factor LIN28 in the mammalian nucleolus during early embryonic development. Development. 2012 Dec;139(24):4514-23. doi: 10.1242/dev.083279. |
In vivo delivery of naked antisense oligos in aged mdx mice: Analysis of dystrophin restoration in skeletal and cardiac muscle
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Citation:
Neuromusc Disord. 2008 Aug;18(8):597-605. Epub 2008 Jul 3. Epub:
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Antisense-mediated exon skipping holds great potential for the treatment of DMD. In mdx mice, functional recovery of skeletal... Delivery Method:
Injection Citation Extract: Vitiello L, Bassi N, Campagnolo P, Zaccariotto E, Occhi G, Malerba A, Pigozzo S, Reggiani C, Ausoni S, Zaglia T, Gamba P, Baroni MD, Ditadi AP. In vivo delivery of naked antisense oligos in aged mdx mice: Analysis of dystrophin restoration in skeletal and cardiac muscle. Neuromusc Disord. 2008 Aug;18(8):597-605. Epub 2008 Jul 3.. |
Inhibition of foot-and-mouth disease virus in cell cultures with antisense Morpholino oligomers
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Citation:
J Virol. 2007 Nov;81(21):11669-80. Epub 2007 Aug 29. Epub:
Not Epub Abstract:
Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed ungulates that can lead to severe losses in... Delivery Method:
peptide-coupled Organism or Cell Type:
Foot-and-mouth disease (FMD) virus Citation Extract: Vagnozzi A, Stein DA, Iversen PL, Rieder E. Inhibition of foot-and-mouth disease virus in cell cultures with antisense Morpholino oligomers. J Virol. 2007 Nov;81(21):11669-80. Epub 2007 Aug 29.. |