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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Controlling gene loss of function in newts with emphasis on lens regeneration
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Citation:
Nature Protocols. 2011;6:593–599 doi:10.1038/nprot.2011.341 Epub:
Not Epub Abstract:
Here we describe a protocol for gene loss of function during regeneration in newts, specifically applied to lens regeneration.... Delivery Method:
Vivo-Morpholino in vivo, Morpholinos and Endo-Porter in cultures Organism or Cell Type:
Notophthalmus viridescens (newt), cell cutlures and in vivo Citation Extract: Tsonis PA, Haynes T, Maki N, Nakamura K, Casco-Robles MM, Yamada S, Miura T, Chiba C, Del Rio-Tsonis K. Controlling gene loss of function in newts with emphasis on lens regeneration. Nature Protocols. 2011;6:593–599 doi:10.1038/nprot.2011.341. |
Deficiency of ribosomal protein S19 during early embryogenesis leads to reduction of erythrocytes in a zebrafish model of Diamond-Blackfan anemia
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Citation:
Hum Mol Genet. 2008 Jul 24. [Epub ahead of print] Epub:
Not Epub Abstract:
Ribosomes are responsible for protein synthesis in all cells. Ribosomal protein S19 (RPS19) is one of the 79 ribosomal proteins... Organism or Cell Type:
zebrafish Citation Extract: Uechi T, Nakajima Y, Chakraborty A, Torihara H, Higa S, Kenmochi N. Deficiency of ribosomal protein S19 during early embryogenesis leads to reduction of erythrocytes in a zebrafish model of Diamond-Blackfan anemia. Hum Mol Genet. 2008 Jul 24. [Epub ahead of print]. |
Design and use of transgenic reporter strains for detecting activity of signaling pathways in Xenopus
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Citation:
Methods. 2013 Jun 28. doi:pii: S1046-2023(13)00240-5. 10.1016/j.ymeth.2013.06.028. [Epub ahead of print] Epub:
Not Epub Abstract:
Embryos and larvae of vertebrate species with external development are ideal subjects for investigating the dynamic... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Tran HT, Vleminckx K. Design and use of transgenic reporter strains for detecting activity of signaling pathways in Xenopus. Methods. 2013 Jun 28. doi:pii: S1046-2023(13)00240-5. 10.1016/j.ymeth.2013.06.028. [Epub ahead of print]. |
Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning
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Citation:
Nat Cell Biol. 2012 Apr 8. doi: 10.1038/ncb2473. [Epub ahead of print] Epub:
Not Epub Abstract:
Clathrin-mediated endocytosis occurs at multiple independent import sites on the plasma membrane, but how these positions are... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Umasankar PK, Sanker S, Thieman JR, Chakraborty S, Wendland B, Tsang M, Traub LM. Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. Nat Cell Biol. 2012 Apr 8. doi: 10.1038/ncb2473. [Epub ahead of print]. |
doublesex/mab3 related-1 (dmrt1) is essential for development of anterior neural plate derivatives in Ciona
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Citation:
Development. 2010 Jul;137(13):2197-203 Epub:
Not Epub Abstract:
Ascidian larvae have a hollow, dorsal central nervous system that shares many morphological features with vertebrate nervous... Delivery Method:
Microinjection Organism or Cell Type:
Ciona savignyi Citation Extract: Tresser J, Chiba S, Veeman M, El-Nachef D, Newman-Smith E, Horie T, Tsuda M, Smith WC. doublesex/mab3 related-1 (dmrt1) is essential for development of anterior neural plate derivatives in Ciona. Development. 2010 Jul;137(13):2197-203. |
Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis
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Citation:
J Biol Chem. 2005 Jun 17;280(24):23262-72. Epub 2005 Apr 18 Epub:
Not Epub Abstract:
Treatment with the protein kinase C activator 12-O-tetradecanoylphorbol 12-acetate (TPA) enables radiation-resistant LNCaP... Delivery Method:
Scrape Delivery Organism or Cell Type:
Cell culture: Human prostate cancer LNCaP, PC-3, DU 145 and CWR22-Rv1 Citation Extract: Truman JP, Gueven N, Lavin M, Leibel S, Kolesnick R, Fuks Z, Haimovitz-Friedman A. Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis. J Biol Chem. 2005 Jun 17;280(24):23262-72. Epub 2005 Apr 18. |
Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR)
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Citation:
FASEB J, 2013 Jan; 27(1):76–85. doi:10.1096/fj.12-213835 Epub:
Not Epub Abstract:
The KDR gene, which participates in angiogenesis and lymphangiogenesis, produces two functionally distinct protein products,... Delivery Method:
in vitro nucleifection; in vivo intravitreal or subconjunctival Vivo-Morpholino injection Organism or Cell Type:
cell culture, mouse cornea Citation Extract: Uehara H, Cho Y, Simonis J, Cahoon J, Archer B, Luo L, Das SK, Singh N, Ambati J, Ambati BK. Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR). FASEB J, 2013 Jan; 27(1):76–85. doi:10.1096/fj.12-213835 . |
Effects of Stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo
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Citation:
Am J Physiol Regul Integr Comp Physiol. 2008 Dec 10. [Epub ahead of print] Epub:
Not Epub Abstract:
Stanniocalcin (STC, formerly called hypocalcin or teleocalcin) is a 50-kDa disulfide-linked homodimeric glycoprotein that was... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Tseng DY, Chou MY, Tseng YC, Hsiao CD, Huang CJ, Kaneko T, Hwang PP. Effects of Stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo. Am J Physiol Regul Integr Comp Physiol. 2008 Dec 10. [Epub ahead of print] . |
Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development
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Citation:
J Cell Sci. 2008 Aug 19. [Epub ahead of print] Epub:
Not Epub Abstract:
The COPII coat assembles on endoplasmic reticulum membranes to coordinate the collection of secretory cargo with the formation... Citation Extract: Townley AK, Feng Y, Schmidt K, Carter DA, Porter R, Verkade P, Stephens DJ. Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development. J Cell Sci. 2008 Aug 19. [Epub ahead of print]. |
Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness
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Citation:
Nat Med. 2006 Aug;12(8):925-32. Epub 2006 Jul 30 Epub:
Not Epub Abstract:
Bidirectional cellular communication is integral to both cancer progression and embryological development. In addition,... Organism or Cell Type:
zebrafish Citation Extract: Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, Nickoloff BJ, Topczewski J, Hendrix MJ. Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nat Med. 2006 Aug;12(8):925-32. Epub 2006 Jul 30. |