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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Neurogenesis and neurite outgrowth in the spinal cord of chicken embryos and in primary cultures of spinal neurons following knockdown of Class III beta tubulin with antisense morpholinos

Authors:
Tucker RP, Tran H, Gong Q
Citation:
Protoplasma. 2008 Sep 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Microtubules are the primary cytoskeletal constituent of extending neurites. We used antisense morpholinos to knock down...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Tucker RP, Tran H, Gong Q. Neurogenesis and neurite outgrowth in the spinal cord of chicken embryos and in primary cultures of spinal neurons following knockdown of Class III beta tubulin with antisense morpholinos. Protoplasma. 2008 Sep 30. [Epub ahead of print].

Ngs (notochord granular surface) encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish

Authors:
Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, Liu H, Zhang Q, Sodmergen D, Lin S, Zhang B
Citation:
J Biol Chem. 2012;[Epub ahead of print] doi:10.1074/jbc.M112.379172
Epub:
Not Epub
Abstract:
Notochord is an important organ involved in embryonic patterning and locomotion. In zebrafish, mature notochord consists of a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, Liu H, Zhang Q, Sodmergen D, Lin S, Zhang B. Ngs (notochord granular surface) encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish. J Biol Chem. 2012;[Epub ahead of print] doi:10.1074/jbc.M112.379172.

Nkx2.7 and Nkx2.5 function redundantly and are required for cardiac morphogenesis of zebrafish embryos

Authors:
Tu CT, Yang TC, Tsai HJ
Citation:
PLoS ONE. 2009;4(1):e4249. Epub 2009 Jan 22
Epub:
Not Epub
Abstract:
BACKGROUND: Nkx2.7 is the tinman-related gene, as well as orthologs of Nkx2.5 and Nkx-2.3. Nkx2.7 and Nkx2.5 express in...
Organism or Cell Type:
zebrafish
Citation Extract:
Tu CT, Yang TC, Tsai HJ. Nkx2.7 and Nkx2.5 function redundantly and are required for cardiac morphogenesis of zebrafish embryos. PLoS ONE. 2009;4(1):e4249. Epub 2009 Jan 22.

Novel Targeting Of COX-2 pre-mRNA Using Antisense Morpholino Oligonucleotides Directed To The 3' Acceptor And 5' Donor Splice Sites Of Exon 4: Suppression Of COX-2 Activity In Human Amnion-Derived WISH And Myometrial Cells

Authors:
Tyson-Capper AJ, Europe-Finner GN
Citation:
Mol Pharmacol. 2006 Mar;69(3):796-804. Epub 2005 Dec 14.
Epub:
Not Epub
Abstract:
Increased expression of COX-2 has been implicated in the onset of both term and preterm labour. In this context both selective...
Delivery Method:
Endo-Porter and Special Delivery
Organism or Cell Type:
cell culture: human myometrial and WISH cells
Citation Extract:
Tyson-Capper AJ, Europe-Finner GN. Novel Targeting Of COX-2 pre-mRNA Using Antisense Morpholino Oligonucleotides Directed To The 3' Acceptor And 5' Donor Splice Sites Of Exon 4: Suppression Of COX-2 Activity In Human Amnion-Derived WISH And Myometrial Cells. Mol Pharmacol. 2006 Mar;69(3):796-804. Epub 2005 Dec 14..

Novel Targeting Of COX-2 pre-mRNA Using Antisense Morpholino Oligonucleotides: Suppression Of Cox-2 Activity In Human Myometrial cells And Amnion-Derived WISH Cells

Authors:
Tyson-Capper AJ, Europe-Finner GN
Citation:
FASEB J, Mar 2006; 20: A72
Epub:
Not Epub
Abstract:
Increased expression of COX-2 has been implicated in the onset of both term and preterm labour. In this context both selective...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human myometrial and WISH cells
Citation Extract:
Tyson-Capper AJ, Europe-Finner GN. Novel Targeting Of COX-2 pre-mRNA Using Antisense Morpholino Oligonucleotides: Suppression Of Cox-2 Activity In Human Myometrial cells And Amnion-Derived WISH Cells. FASEB J, Mar 2006; 20: A72.

Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK

Authors:
Unterseher F, Hefele JA, Giehl K, De Robertis EM, Wedlich D, Schambony A
Citation:
EMBO J. 2004 Aug 18;23(16):3259-69. Epub 2004 Aug 5
Epub:
Not Epub
Abstract:
Convergent extension movements occur ubiquitously in animal development. This special type of cell movement is controlled by...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Unterseher F, Hefele JA, Giehl K, De Robertis EM, Wedlich D, Schambony A. Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. EMBO J. 2004 Aug 18;23(16):3259-69. Epub 2004 Aug 5.

Probing e-cadherin endocytosis by morpholino-mediated rab5 knockdown in zebrafish

Authors:
Ulrich F, Heisenberg CP
Citation:
Methods Mol Biol. 2008;440:371-87
Epub:
Not Epub
Abstract:
The controlled internalization of membrane receptors and lipids is crucial for cells to control signaling pathways and interact...
Organism or Cell Type:
zebrafish
Citation Extract:
Ulrich F, Heisenberg CP. Probing e-cadherin endocytosis by morpholino-mediated rab5 knockdown in zebrafish. Methods Mol Biol. 2008;440:371-87.

Promotion of pyrimidine motif triplex formation by morpholino modification of triplex-forming oligonucleotide: kinetic and thermodynamic studies

Authors:
Torigoe H, Kawahashi K, Tamura Y
Citation:
Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):1019-21
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
not applicable
Organism or Cell Type:
Abiotic system
Citation Extract:
Torigoe H, Kawahashi K, Tamura Y. Promotion of pyrimidine motif triplex formation by morpholino modification of triplex-forming oligonucleotide: kinetic and thermodynamic studies. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):1019-21.

Promotion of triplex formation by morpholino modification: thermodynamic and kinetic studies.

Authors:
Torigoe H, Kawahashi K, Tamura Y.
Citation:
Nucleic Acids Res Suppl. 2003;(3):157-8.
Epub:
Not Epub
Abstract:
We examined the effect of morpholino (MOR) backbone modification of triplex-forming oligonucleotide (TFO) on the pyrimidine...
Citation Extract:
Torigoe H, Kawahashi K, Tamura Y.. Promotion of triplex formation by morpholino modification: thermodynamic and kinetic studies.. Nucleic Acids Res Suppl. 2003;(3):157-8..

Propionic and Methylmalonic Acidemia: Antisense Therapeutics for Intronic Variations Causing Aberrantly Spliced Messenger RNA

Authors:
Ugarte M, Aguado C, Desviat LR, Sanchez-Alcudia R, Rincon A, Perez B
Citation:
Am J Hum Genet. 2007 Oct 26;81(6) [Epub ahead of print]
Epub:
Not Epub
Abstract:
We describe the use of antisense morpholino oligonucleotides (AMOs) to restore normal splicing caused by intronic molecular...
Organism or Cell Type:
cell culture
Citation Extract:
Ugarte M, Aguado C, Desviat LR, Sanchez-Alcudia R, Rincon A, Perez B. Propionic and Methylmalonic Acidemia: Antisense Therapeutics for Intronic Variations Causing Aberrantly Spliced Messenger RNA. Am J Hum Genet. 2007 Oct 26;81(6) [Epub ahead of print] .

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