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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
The Cytoskeletal Protein Zyxin Inhibits Retinoic Acid Signaling by Destabilizing the Maternal mRNA of the RXRγ Nuclear Receptor
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Citation:
Inter J Mol Sci. 2022;23(10):5627. doi:10.3390/ijms23105627 Epub:
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Zyxin is an LIM-domain-containing protein that regulates the assembly of F-actin filaments in cell contacts. Additionally, as a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Parshina EA, Orlov EE, Zaraisky AG, Martynova NY. The Cytoskeletal Protein Zyxin Inhibits Retinoic Acid Signaling by Destabilizing the Maternal mRNA of the RXRγ Nuclear Receptor. Inter J Mol Sci. 2022;23(10):5627. doi:10.3390/ijms23105627. |
Transmembrane Protein 184A and Syndecan-4 function in the same pathway to promote angiogenesis
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Citation:
FASEB J. 2022;[Epub] doi:10.1096/fasebj.2022.36.S1.L8077 Epub:
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Morpholino (MO) knockdown (KD) of the novel vascular heparin receptor, Transmembrane protein 184A (TMEM184A), increases... Delivery Method:
injection Organism or Cell Type:
zebrafish Citation Extract: Altenburg LM, O'Toole RA, Ciabattoni GO, Papov IV, Pasch LM, Maslonka BE, Lowe-Krentz LJ. Transmembrane Protein 184A and Syndecan-4 function in the same pathway to promote angiogenesis. FASEB J. 2022;[Epub] doi:10.1096/fasebj.2022.36.S1.L8077. |
microRNA-34a modulates the senescence of activated hepatic stellate cells in alcohol-associated liver injury
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Citation:
FASEB J. 2022;[Epub] doi:10.1096/fasebj.2022.36.S1.R4231 Epub:
Not Epub Abstract:
Background: Reversion of activated hepatic stellate cells (HSCs) to quiescence is likely to be a promising pathway in liver... Organism or Cell Type:
mice Citation Extract: Slevin E, Wan Y, Harrison K, Zhang Y, Li X, Li T, Lorenzo SR, Xu W, Klaunig JE, Shetty AK, Meng F. microRNA-34a modulates the senescence of activated hepatic stellate cells in alcohol-associated liver injury. FASEB J. 2022;[Epub] doi:10.1096/fasebj.2022.36.S1.R4231. |
Casimersen for the treatment of Duchenne muscular dystrophy
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Citation:
Trends Pharmacol Sci. 2022 May 14:S0165-6147(22)00089-X. doi: 10.1016/j.tips.2022.04.009. Online ahead of print Epub:
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Casimersen is a single-stranded, antisense phosphorodiamidate morpholino oligonucleotide where six-membered morpholino rings... Citation Extract: Zakeri SE, Pradeep SP, Kasina V, Laddha AP, Manautou JE, Bahal R. Casimersen for the treatment of Duchenne muscular dystrophy. Trends Pharmacol Sci. 2022 May 14:S0165-6147(22)00089-X. doi: 10.1016/j.tips.2022.04.009. Online ahead of print. |
SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine
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Citation:
Cell Rep. 2022 May 10;39(6):110813. doi: 10.1016/j.celrep.2022.110813 Epub:
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Serine/arginine-rich splicing factor 3 (SRSF3) regulates mRNA alternative splicing of more than 90% of protein-coding genes,... Organism or Cell Type:
cell culture: human pancreatic cancer Panc1 and BXPC3 Citation Extract: Wang ZW, Pan JJ, Hu JF, Zhang JQ, Huang L, Huang Y, Liao CY, Yang C, Chen ZW, Wang YD, Shen BY, Tian YF, Chen S. SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine. Cell Rep. 2022 May 10;39(6):110813. doi: 10.1016/j.celrep.2022.110813. |
The glutathione degrading enzyme, Chac1, is required for calcium signaling in developing zebrafish: redox as an upstream activator of calcium
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Citation:
Biochem J. 2019;476(13):1857-73 Epub:
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Calcium signaling is essential for embryonic development but the signals upstream of calcium are only partially understood.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yadav S, Chawla B, Khursheed MA, Ramachandran R, Bachhawat AK. The glutathione degrading enzyme, Chac1, is required for calcium signaling in developing zebrafish: redox as an upstream activator of calcium. Biochem J. 2019;476(13):1857-73. |
A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness
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Citation:
J Am Soc Nephrol. 2022 Apr;33(4):732-745. doi:10.1681/ASN.2021101312. Epub 2022 Feb 11 Epub:
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Background: The endocytic reabsorption of proteins in the proximal tubule requires a complex machinery and defects can lead to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Issler N, Afonso S, Weissman I, Jordan K, Cebrian-Serrano A, Meindl K, Dahlke E, Tziridis K, Yan G, Robles-López JM, Tabernero L, Patel V, Kesselheim A, Klootwijk ED, Stanescu HC, Dumitriu S, Iancu D, Tekman M, Mozere M, Jaureguiberry G, Outtandy P, Russell C, Forst AL, Sterner C, Heinl ES, Othmen H, Tegtmeier I, Reichold M, Schiessl IM, Limm K, Oefner P, Witzgall R, Fu L, Theilig F, Schilling A, Shuster Biton E, Kalfon L, Fedida A, Arnon-Sheleg E, Ben Izhak O, Magen D, Anikster Y, Schulze H, Ziegler C, Lowe M, Davies B, Böckenhauer D, Kleta R, Falik Zaccai TC, Warth R. A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness. J Am Soc Nephrol. 2022 Apr;33(4):732-745. doi:10.1681/ASN.2021101312. Epub 2022 Feb 11. |
Different requirements for GATA factors in cardiogenesis are mediated by non-canonical Wnt signaling
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Citation:
Dev Dyn. 2011 Mar;240(3):649-62. doi:10.1002/dvdy.22570. Epub 2011 Feb 8 Epub:
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GATA factors and Wnt signals are key regulators of vertebrate cardiogenesis, but specific roles for individual GATA factors and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Afouda BA, Hoppler S. Different requirements for GATA factors in cardiogenesis are mediated by non-canonical Wnt signaling. Dev Dyn. 2011 Mar;240(3):649-62. doi:10.1002/dvdy.22570. Epub 2011 Feb 8. |
FoxN3 knock-down alters spatio-temporal expression patterns of genes involved in cranial cartilage and muscle development in the African clawed-frog Xenopus laevis
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Citation:
Vertebr Zool. 2020;70(3)455-72. doi:10.26049/VZ70-3-2020-14 Epub:
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What is the gene regulatory network underlying the morphogenesis of the vertebrate head skeleton? A good candidate to approach... Link:
Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Schmidt J, Schuff M, Naumann B, Olsson L. FoxN3 knock-down alters spatio-temporal expression patterns of genes involved in cranial cartilage and muscle development in the African clawed-frog Xenopus laevis. Vertebr Zool. 2020;70(3)455-72. doi:10.26049/VZ70-3-2020-14. |
Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2
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Citation:
Development. 2022 May 1;149(9):dev190421. doi: 10.1242/dev.190421. Epub 2022 May 9 Epub:
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The endocardium plays important roles in the development and function of the vertebrate heart; however, few molecular markers... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Capon SJ, Uribe V, Dominado N, Ehrlich O, Smith KA. Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2. Development. 2022 May 1;149(9):dev190421. doi: 10.1242/dev.190421. Epub 2022 May 9. |