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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Antisense oligonucleotides targeting exon 11 are able to partially rescue the Neurofibromatosis Type 2 phenotype in vitro
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.02.11.479859 Epub:
Not Epub Abstract:
Neurofibromatosis type 2 (NF2) is an autosomal dominant condition characterized by the development of multiple tumours of the... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human primary neurofibromatosis cells Citation Extract: Catasus N, Rosas I, Bonache S, Negro A, Plana A, Salvador H, Serra E, Blanco I, Castellanos E. Antisense oligonucleotides targeting exon 11 are able to partially rescue the Neurofibromatosis Type 2 phenotype in vitro. bioRxiv. 2022;[preprint] doi:10.1101/2022.02.11.479859 . |
The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation
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Citation:
Elife. 2022 Feb 10;11:e71928. doi: 10.7554/eLife.71928. Online ahead of print Epub:
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Vertebrate Delta/Notch signaling involves multiple ligands, receptors and transcription factors. Delta endocytosis - a critical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Saraswathy VM, Kurup AJ, Sharma P, Polès S, Poulain M, Fürthauer M. The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation. Elife. 2022 Feb 10;11:e71928. doi: 10.7554/eLife.71928. Online ahead of print. |
Planktonic sea urchin larvae change their swimming direction in response to strong photoirradiation
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Citation:
PLoS Genet. 2022;18(2):e1010033. doi:10.1371/journal.pgen.1010033 Epub:
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To survive, organisms need to precisely respond to various environmental factors, such as light and gravity. Among these, light... Delivery Method:
microinjection Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Yaguchi S, Taniguchi Y, Suzuki H, Kamata M, Yaguchi J. Planktonic sea urchin larvae change their swimming direction in response to strong photoirradiation. PLoS Genet. 2022;18(2):e1010033. doi:10.1371/journal.pgen.1010033. |
Mcm5 Represses Endodermal Migration through Cxcr4a-itgb1b Cascade Instead of Cell Cycle Control
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Citation:
Biomolecules. 2022;12(2):286. doi:10.3390/biom12020286 Epub:
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Minichromosome maintenance protein 5 (MCM5) is a critical cell cycle regulator; its role in DNA replication is well known, but... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Y, Xia J, Liu M, Chen B, Yang M, Yu X, Ou Y, Li S, Liu X, Feng Y, Su B, Huang S. Mcm5 Represses Endodermal Migration through Cxcr4a-itgb1b Cascade Instead of Cell Cycle Control. Biomolecules. 2022;12(2):286. doi:10.3390/biom12020286. |
Pluripotency factors determine gene expression repertoire at zygotic genome activation
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Citation:
Nat Commun 13, 788 (2022). https://doi.org/10.1038/s41467-022-28434-1 Epub:
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Awakening of zygotic transcription in animal embryos relies on maternal pioneer transcription factors. The interplay of global... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gao M, Veil M, Rosenblatt M, Riesle AJ, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Ulianov SV, Timmer J, Onichtchouk D. Pluripotency factors determine gene expression repertoire at zygotic genome activation. Nat Commun 13, 788 (2022). https://doi.org/10.1038/s41467-022-28434-1. |
Functional Analysis of Zebrafish socs4a: Impacts on the Notochord and Sensory Function
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Citation:
Brain Sci. 2022;12(2):241. doi:10.3390/brainsci12020241 Epub:
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The suppressor of cytokine signaling (SOCS) proteins play important roles in cytokine and growth factor signaling, where they... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Trengove M, Wyett R, Liongue C, Ward AC. Functional Analysis of Zebrafish socs4a: Impacts on the Notochord and Sensory Function. Brain Sci. 2022;12(2):241. doi:10.3390/brainsci12020241. |
PPMO-mediated exon skipping induces uniform sarcolemmal dystrophin rescue with dose-dependent restoration of circulating microRNA biomarkers and muscle biophysical properties
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.01.25.477672 Epub:
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Duchenne muscular dystrophy (DMD) is a paediatric muscle-wasting disorder caused by genetic loss of the gene encoding the... Delivery Method:
i.v. injection Organism or Cell Type:
mice, mdx Citation Extract: Chwalenia K, Oieni J, Zemła J, Lekka M, Ahlskog N, Coenen-Stass AML, McClorey G, Wood MJA, Lomonosova Y, Roberts TC. PPMO-mediated exon skipping induces uniform sarcolemmal dystrophin rescue with dose-dependent restoration of circulating microRNA biomarkers and muscle biophysical properties. bioRxiv. 2022;[preprint] doi:10.1101/2022.01.25.477672. |
Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells
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Citation:
Eur J Immunol. 2016 Aug;46(8):1854-66. doi: 10.1002/eji.201546252. Epub 2016 Jun 8 Epub:
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Apolipoproteins L (ApoLs) are Bcl-2-like proteins expressed under inflammatory conditions in myeloid and endothelial cells. We... Delivery Method:
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cell culture: CD8α+ MutuDCs (dendritic cells) Citation Extract: Uzureau S, Coquerelle C, Vermeiren C, Uzureau P, Van Acker A, Pilotte L, Monteyne D, Acolty V, Vanhollebeke B, Van den Eynde B, Pérez-Morga D, Moser M, Pays E. Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells. Eur J Immunol. 2016 Aug;46(8):1854-66. doi: 10.1002/eji.201546252. Epub 2016 Jun 8. |
The H3.3 chaperone Hira complex orchestrates oocyte developmental competence
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Citation:
Development. 2022 Feb 3:dev.200044. doi: 10.1242/dev.200044. Online ahead of print Epub:
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Successful reproduction requires an oocyte competent to sustaining early embryo development. By the end of oogenesis, the... Delivery Method:
microinjection Organism or Cell Type:
mouse embryo Citation Extract: Smith R, Susor A, Ming H, Tait J, Conti M, Jiang Z, Lin CJ. The H3.3 chaperone Hira complex orchestrates oocyte developmental competence. Development. 2022 Feb 3:dev.200044. doi: 10.1242/dev.200044. Online ahead of print. |
PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma
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Citation:
Blood. 2022 Apr 14;139(15):2316-2337. doi: 10.1182/blood.2021014011. PMID: 35108359 Epub:
Yes Abstract:
The differentiation of B cells into plasmablasts (PBs) and then plasma cells (PCs) is associated with extensive cell... Delivery Method:
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cell culture: human B cell Citation Extract: Haas M, Caron G, Chatonnet F, Manenti S, Alaterre E, Devin J, Delaloy C, Bertolin G, Viel R, Pignarre A, Llamas-Gutierrez F, Marchalot A, Decaux O, Tarte K, Delpy L, Moreaux J, Fest T. PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma. Blood. 2022 Apr 14;139(15):2316-2337. doi: 10.1182/blood.2021014011. PMID: 35108359. |