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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish
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Citation:
Front Biosci (Landmark Ed). 2022 Mar 28;27(4):110. doi: 10.31083/j.fbl2704110 Epub:
Not Epub Abstract:
Background: Colony-stimulating factor 3 (CSF3), more commonly known as granulocyte colony-stimulating factor (G-CSF), acts via... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meier AB, Basheer F, Sertori R, Laird M, Liongue C, Ward AC. Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish. Front Biosci (Landmark Ed). 2022 Mar 28;27(4):110. doi: 10.31083/j.fbl2704110. |
Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells
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Citation:
Stem Cells Dev. 2022 Apr 25. doi: 10.1089/scd.2021.0347. Online ahead of print Epub:
Not Epub Abstract:
Cellular metabolism plays both an active and passive role in embryonic development, pluripotency, and cell-fate decisions.... Delivery Method:
cell culture: murine embryonic stem cells Citation Extract: Dierolf JG, Hunter HLM, Watson AJ, Betts DH. Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells. Stem Cells Dev. 2022 Apr 25. doi: 10.1089/scd.2021.0347. Online ahead of print. |
STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
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Citation:
Cell Death Discov. 2023 Jul 5;9(1):226. doi: 10.1038/s41420-023-01507-w. PMID: 37407568; PMCID: PMC10323006 Epub:
Not Epub Abstract:
STAT3 and HIF1α are two fundamental transcription factors involved in many merging processes, like angiogenesis, metabolism,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dinarello A, Betto RM, Diamante L, Tesoriere A, Ghirardo R, Cioccarelli C, Meneghetti G, Peron M, Laquatra C, Tiso N, Martello G, Argenton F. STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia. Cell Death Discov. 2023 Jul 5;9(1):226. doi: 10.1038/s41420-023-01507-w. PMID: 37407568; PMCID: PMC10323006. |
Cell Clusters Containing Intestinal Stem Cells Line the Zebrafish Intestine Intervillus Pocket
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Citation:
iScience. 2022;104280 [Epub]. doi:10.1016/j.isci.2022.104280 Epub:
Yes Abstract:
In the mammalian intestine, stem cells (ISCs) replicate in basal crypts, translocate along the villus, and undergo cell death.... Delivery Method:
Vivo-Morphoino intestinal gavage Organism or Cell Type:
zebrafish Citation Extract: Tavakoli S, Zhu S, Matsudaira P. Cell Clusters Containing Intestinal Stem Cells Line the Zebrafish Intestine Intervillus Pocket. iScience. 2022;104280 [Epub]. doi:10.1016/j.isci.2022.104280. |
VDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway
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Citation:
Cell Death Dis. 2022 Apr 21;13(4):393. doi: 10.1038/s41419-022-04755-3 Epub:
Not Epub Abstract:
The voltage-dependent anion channel 1 (VDAC1) was first described as a mitochondrial porin that mediates the flux of... Delivery Method:
subretinal injection Organism or Cell Type:
male and female Long Evans rats (Rattus norvegicus) Citation Extract: de Sousa E, Móvio MI, de Lima-Vasconcellos TH, Dos Santos GB, Dos Santos Gomes T, Walter LT, da Silva DA, Rodrigues T, Cerchiaro G, Kihara AH. VDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway. Cell Death Dis. 2022 Apr 21;13(4):393. doi: 10.1038/s41419-022-04755-3. |
The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio
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Citation:
Proc Nat Acad Sci USA. 2022;117(17):e2112225119 [Epub] doi:10.1073/pnas.2112225119 Epub:
Not Epub Abstract:
Hypocretin (Hcrt), also known as orexin, neuropeptide signaling stabilizes sleep and wakefulness in all vertebrates. A lack of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holm A, Possovre M-L, Bandarabadi M, Moseholm KF, Justinussen JL, Bozic I, Lemcke R, Arribat Y, Amati F, Silahtaroglu A, Juventin M, Adamantidis A, Tafti M, Kornum BR. The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio. Proc Nat Acad Sci USA. 2022;117(17):e2112225119 [Epub] doi:10.1073/pnas.2112225119. |
Therapeutic Potential of CKD-504, a Novel Selective Histone Deacetylase 6 Inhibitor, in a Zebrafish Model of Neuromuscular Junction Disorders
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Citation:
Mol Cells. 2022;45(4):231-42. doi:10.14348/molcells.2022.5005 Epub:
Not Epub Abstract:
The neuromuscular junction (NMJ), which is a synapse for signal transmission from motor neurons to muscle cells, has emerged as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jeong HS, Kim HJ, Kim D-H, Chung KW, Choi B-O, Lee JE. Therapeutic Potential of CKD-504, a Novel Selective Histone Deacetylase 6 Inhibitor, in a Zebrafish Model of Neuromuscular Junction Disorders. Mol Cells. 2022;45(4):231-42. doi:10.14348/molcells.2022.5005. |
Vasa nucleates asymmetric translation along the mitotic spindle during unequal cell divisions
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Citation:
Nat Commun. 2022 Apr 20;13(1):2145. doi: 10.1038/s41467-022-29855-8 Epub:
Not Epub Abstract:
mRNA translation on the spindle is hypothesized to be an essential strategy for the localized production of cell regulators.... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Fernandez-Nicolas A, Uchida A, Poon J, Yajima M. Vasa nucleates asymmetric translation along the mitotic spindle during unequal cell divisions. Nat Commun. 2022 Apr 20;13(1):2145. doi: 10.1038/s41467-022-29855-8. |
Insm1-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone Nematostella vectensis
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Citation:
Sci Adv. 2022 Apr 22;8(16):eabi7109. doi:10.1126/sciadv.abi7109. Epub 2022 Apr 20 Epub:
Not Epub Abstract:
Neurons are highly specialized cells present in nearly all animals, but their evolutionary origin and relationship to other... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Tournière O, Gahan JM, Busengdal H, Bartsch N, Rentzsch F. Insm1-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone Nematostella vectensis. Sci Adv. 2022 Apr 22;8(16):eabi7109. doi:10.1126/sciadv.abi7109. Epub 2022 Apr 20. |
A posttranscriptional mechanism that controls Ptbp1 abundance in the Xenopus epidermis
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Citation:
Mol Cell Biol. 2015 Feb;35(4):758-68. doi: 10.1128/MCB.01040-14. Epub 2014 Dec 15 Epub:
Not Epub Abstract:
The output of alternative splicing depends on the cooperative or antagonistic activities of several RNA-binding proteins (RBPs... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Méreau A, Anquetil V, Lerivray H, Viet J, Schirmer C, Audic Y, Legagneux V, Hardy S, Paillard L. A posttranscriptional mechanism that controls Ptbp1 abundance in the Xenopus epidermis. Mol Cell Biol. 2015 Feb;35(4):758-68. doi: 10.1128/MCB.01040-14. Epub 2014 Dec 15. |