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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.08.459391 Epub:
Not Epub Abstract:
Although thrombosis has been extensively studied using various animal models, however, our understanding of the underlying... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ding Y, Li Y, Zhang CQ, Liu F. The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.08.459391. |
Lmo7 recruits myosin II heavy chain to induce apical constriction in Xenopus ectoderm
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443820 Epub:
Not Epub Abstract:
Apical constriction, or reduction of the apical domain, underlies many morphogenetic events during development, such as furrow... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Matsuda M, Chu C-W, Sokol SY. Lmo7 recruits myosin II heavy chain to induce apical constriction in Xenopus ectoderm. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443820. |
Admp regulates tail bending by controlling the intercalation of the ventral epidermis through myosin phosphorylation
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.21.461063 Epub:
Not Epub Abstract:
Chordate tailbud embryos have similar morphological features, including a bending tail. A recent study revealed that the... Delivery Method:
microinjection Organism or Cell Type:
Ciona robusta (C. intestinalis type A, ascidian) Citation Extract: Kogure YS, Muraoka H, Koizumi WC, Gelin-alessi R, Godard B, Heisenberg CP, Oka K, Hotta K. Admp regulates tail bending by controlling the intercalation of the ventral epidermis through myosin phosphorylation. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.21.461063. |
Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development
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Citation:
Antioxidants (Basel). 2021;10(10):1636. doi:10.3390/antiox10101636 Epub:
Not Epub Abstract:
Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of antioxidants, and have... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lee H, Lee NY, Kim Y, Choi H-S, Ismail T, Ryu H-Y, Cho D-H, Ryoo ZY, Lee D-S, Kwon TK, Park TJ, Kwon T, Lee H-S. Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development. Antioxidants (Basel). 2021;10(10):1636. doi:10.3390/antiox10101636. |
Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish
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Citation:
Int J Mol Sci. 2021;22(20):11217. doi:10.3390/ijms222011217 Epub:
Not Epub Abstract:
Compensatory hepatocyte proliferation and other liver regenerative processes are activated to sustain normal physiological... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Chiang K-Y, Li Y-W, Li Y-H, Huang S-J, Wu C-L, Gong H-Y, Wu J-L. Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish. Int J Mol Sci. 2021;22(20):11217. doi:10.3390/ijms222011217. |
A recessive variant in TFAM causes mtDNA depletion associated with primary ovarian insufficiency, seizures, intellectual disability and hearing loss
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Citation:
Hum Genet. 2021 Oct 13. doi: 10.1007/s00439-021-02380-2. Online ahead of print Epub:
Yes Abstract:
Mitochondrial disorders are collectively common, genetically heterogeneous disorders in both pediatric and adult populations.... Organism or Cell Type:
zebrafish Citation Extract: Ullah F, Rauf W, Khan K, Khan S, Bell KM, de Oliveira VC, Tariq M, Bakhshalizadeh S, Touraine P, Katsanis N, Sinclair A, He S, Tucker EJ, Baig SM, Davis EE. A recessive variant in TFAM causes mtDNA depletion associated with primary ovarian insufficiency, seizures, intellectual disability and hearing loss. Hum Genet. 2021 Oct 13. doi: 10.1007/s00439-021-02380-2. Online ahead of print. |
Antisense-Mediated Down-Regulation of Factor V-Short Splicing in a Liver Cell Line Model
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Citation:
Appl Sci. 2021;11(20):9621. doi:0.3390/app11209621 Epub:
Not Epub Abstract:
Coagulation factor V (FV) is a liver-derived protein encoded by the F5 gene. Alternative splicing of F5 exon 13 produces a low-... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HepG2 Citation Extract: Todaro AM, Hackeng TM, Castoldi E. Antisense-Mediated Down-Regulation of Factor V-Short Splicing in a Liver Cell Line Model. Appl Sci. 2021;11(20):9621. doi:0.3390/app11209621 . |
Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish -- implications for neurodevelopmental disorders
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Citation:
Transl Psychiatry. 2021;11:529. doi:10.1038/s41398-021-01651-w Epub:
Not Epub Abstract:
Recent advances in the genetics of neurodevelopmental disorders (NDDs) have identified the transcription factor FOXP2 as one of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lüffe TM, D’Orazio A, Bauer M, Gioga Z, Schoeffler V, Lesch K-P, Romanos Ml, Drepper C, Lillesaar C. Increased locomotor activity via regulation of GABAergic signalling in foxp2 mutant zebrafish -- implications for neurodevelopmental disorders. Transl Psychiatry. 2021;11:529. doi:10.1038/s41398-021-01651-w. |
Antisense oligonucleotides: absorption, distribution, metabolism, and excretion
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Citation:
Expert Opin Drug Metab Toxicol. 2021 Oct 13. doi: 10.1080/17425255.2021.1992382. Online ahead of print Epub:
Yes Abstract:
Introduction: Antisense oligonucleotides (ASOs) have emerged as a promising novel drug modality that aims to address unmet... Citation Extract: Shadid M, Badawi M, Abulrob A. Antisense oligonucleotides: absorption, distribution, metabolism, and excretion. Expert Opin Drug Metab Toxicol. 2021 Oct 13. doi: 10.1080/17425255.2021.1992382. Online ahead of print. |
CNPase, a 2',3'-Cyclic-nucleotide 3'-phosphodiesterase, as a Therapeutic Target to Attenuate Cardiac Hypertrophy by Enhancing Mitochondrial Energy Production
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Citation:
Int J Mol Sci. 2021 Oct 6;22(19):10806. doi: 10.3390/ijms221910806 Epub:
Not Epub Abstract:
Heart failure is the end-stage of all cardiovascular diseases with a ~25% 5-year survival rate, and insufficient mitochondrial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tan KS, Wang D, Lu Z, Zhang Y, Li S, Lin Y, Tan W. CNPase, a 2',3'-Cyclic-nucleotide 3'-phosphodiesterase, as a Therapeutic Target to Attenuate Cardiac Hypertrophy by Enhancing Mitochondrial Energy Production. Int J Mol Sci. 2021 Oct 6;22(19):10806. doi: 10.3390/ijms221910806. |