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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation

Authors:
Hadzhiev Y, Wheatley L, Cooper L, Ansaloni F, Whalley C, Chen Z, Finaurini S, Gustincich S, Sanges R, Burgess S, Beggs A, Müller F
Citation:
Dev Cell. 2023 Jan 23;58(2):155-170.e8. doi: 10.1016/j.devcel.2022.12.007. PMID: 36693321; PMCID: PMC9904021
Epub:
Not Epub
Abstract:
In anamniote embryos, the major wave of zygotic genome activation starts during the mid-blastula transition. However, some...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9904021/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hadzhiev Y, Wheatley L, Cooper L, Ansaloni F, Whalley C, Chen Z, Finaurini S, Gustincich S, Sanges R, Burgess S, Beggs A, Müller F. The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation. Dev Cell. 2023 Jan 23;58(2):155-170.e8. doi: 10.1016/j.devcel.2022.12.007. PMID: 36693321; PMCID: PMC9904021.

Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process

Authors:
Tessadori F, Tsingos E, Colizzi ES, Kruse F, van den Brink SC, van den Boogaard M, Christoffels VM, Merks RM, Bakkers J
Citation:
Elife. 2021 Aug 10;10:e61733. doi: 10.7554/eLife.61733
Epub:
Not Epub
Abstract:
Organ laterality refers to the left-right asymmetry in disposition and conformation of internal organs and is established...
Link:
https://elifesciences.org/articles/61733
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tessadori F, Tsingos E, Colizzi ES, Kruse F, van den Brink SC, van den Boogaard M, Christoffels VM, Merks RM, Bakkers J. Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process. Elife. 2021 Aug 10;10:e61733. doi: 10.7554/eLife.61733.

Who is the best surrogate for germ stem cell transplantation in fish?

Authors:
Franěk R, Cheng Y, Fučíková M, Kašpar V, Xie X, Shah MA, Linhart O, Šauman I, Pšenička
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.09.455047
Epub:
Not Epub
Abstract:
Surrogate reproduction technology in fish has potential for aquaculture as well as endangered species preservation and...
Link:
https://www.biorxiv.org/content/10.1101/2021.08.09.455047v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Franěk R, Cheng Y, Fučíková M, Kašpar V, Xie X, Shah MA, Linhart O, Šauman I, Pšenička. Who is the best surrogate for germ stem cell transplantation in fish?. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.09.455047.

Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing

Authors:
Presnell JS, Browne WE
Citation:
Development. 2021 Aug 10:dev.199771. doi: 10.1242/dev.199771. Online ahead of print
Epub:
Yes
Abstract:
The Krüppel-like factor (Klf) gene family encodes for transcription factors that play an important role in the regulation of...
Link:
https://journals.biologists.com/dev/article-abstract/doi/10.1242/dev.199771/271214/Kruppel-like-factor-gene-function-in-the
Organism or Cell Type:
Mnemiopsis leidyi (ctenophore)
Citation Extract:
Presnell JS, Browne WE. Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing. Development. 2021 Aug 10:dev.199771. doi: 10.1242/dev.199771. Online ahead of print.

Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development

Authors:
Kuil LE, MacKenzie KC, Tang CS, Windster JD, Le TL, Karim A, de Graaf BM, van der Helm R, van Bever Y, Sloots CEJ, Meeussen C, Tibboel D, de Klein A, Wijnen RMH, Amiel J, Lyonnet S, Garcia-Barcelo M-M, Tam PKH, Alves MM, Brooks AS, Hofstra RMW, Brosens E
Citation:
PLoS Genet. 2021;17(8):e1009698. doi:10.1371/journal.pgen.1009698
Epub:
Not Epub
Abstract:
Hirschsprung disease (HSCR) is a complex genetic disease characterized by absence of ganglia in the intestine. HSCR etiology...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1009698
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kuil LE, MacKenzie KC, Tang CS, Windster JD, Le TL, Karim A, de Graaf BM, van der Helm R, van Bever Y, Sloots CEJ, Meeussen C, Tibboel D, de Klein A, Wijnen RMH, Amiel J, Lyonnet S, Garcia-Barcelo M-M, Tam PKH, Alves MM, Brooks AS, Hofstra RMW, Brosens E. Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development. PLoS Genet. 2021;17(8):e1009698. doi:10.1371/journal.pgen.1009698.

Deep learning to design nuclear-targeting abiotic miniproteins

Authors:
Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL
Citation:
Nat Chem. 2021;[Epub ahead of print] doi:10.1038/s41557-021-00766-3
Epub:
Not Epub
Abstract:
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space...
Link:
https://www.nature.com/articles/s41557-021-00766-3
Delivery Method:
protein-linked
Organism or Cell Type:
cell culture
Citation Extract:
Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Deep learning to design nuclear-targeting abiotic miniproteins. Nat Chem. 2021;[Epub ahead of print] doi:10.1038/s41557-021-00766-3.

Disc and Actin-Associated Protein 1 Influence Host Attachment in the Intestinal Parasite Giardia lamblia

Authors:
Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.06.455446
Epub:
Not Epub
Abstract:
The deep-branching eukaryote Giardia lamblia is an extracellular parasite that attaches to the host intestine via a microtubule...
Link:
https://www.biorxiv.org/content/10.1101/2021.08.06.455446v1
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR. Disc and Actin-Associated Protein 1 Influence Host Attachment in the Intestinal Parasite Giardia lamblia. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.06.455446.

Neuron Navigator 3 (NAV3) is Required for Heart Development

Authors:
Lv F, Yuan F, Lu X, Ge X, Shi L, Wang X, Liu D, Chen C
Citation:
Research Square. 2021;[preprint] doi:10.21203/rs.3.rs-734749/v1
Epub:
Not Epub
Abstract:
Background: As a tightly controlled biological process, cardiogenesis requires the specification and migration of a suite of...
Link:
https://www.researchsquare.com/article/rs-734749/v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lv F, Yuan F, Lu X, Ge X, Shi L, Wang X, Liu D, Chen C. Neuron Navigator 3 (NAV3) is Required for Heart Development. Research Square. 2021;[preprint] doi:10.21203/rs.3.rs-734749/v1.

Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury

Authors:
Cui C, Wang LF, Huang SB, Zhao P, Chen YQ, Wu YB, Qiao CM, Zhao WJ, Shen YQ
Citation:
Exp Neurol. 2021 Aug 4:113831. doi: 10.1016/j.expneurol.2021.113831. Online ahead of print
Epub:
Yes
Abstract:
In strong contrast to limited repair within the mammalian central nervous system, the spinal cord of adult zebrafish is capable...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0014488621002399
Organism or Cell Type:
zebrafish
Citation Extract:
Cui C, Wang LF, Huang SB, Zhao P, Chen YQ, Wu YB, Qiao CM, Zhao WJ, Shen YQ. Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury. Exp Neurol. 2021 Aug 4:113831. doi: 10.1016/j.expneurol.2021.113831. Online ahead of print.

Endothelial Semaphorin 3fb regulates Vegf pathway-mediated angiogenic sprouting

Authors:
Watterston C, Halabi R, McFarlane S, Childs SJ
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.03.454978
Epub:
Not Epub
Abstract:
Vessel growth integrates diverse extrinsic signals with intrinsic signaling cascades to coordinate cell migration and sprouting...
Link:
https://www.biorxiv.org/content/10.1101/2021.08.03.454978v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Watterston C, Halabi R, McFarlane S, Childs SJ. Endothelial Semaphorin 3fb regulates Vegf pathway-mediated angiogenic sprouting. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.03.454978.

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