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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Loss of Ift74 Leads to Slow Photoreceptor Degeneration and Ciliogenesis Defects in Zebrafish
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Citation:
Int J Mol Sci. 2021;22(17):9329. doi:10.3390/ijms22179329 Epub:
Not Epub Abstract:
Cilia are microtubule-based structures projecting from the cell surface that perform diverse biological functions. Ciliary... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu P, Xu J, Wang Y, Zhao C. Loss of Ift74 Leads to Slow Photoreceptor Degeneration and Ciliogenesis Defects in Zebrafish. Int J Mol Sci. 2021;22(17):9329. doi:10.3390/ijms22179329. |
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis
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Citation:
Cell Res. 2021 Sep 3. doi: 10.1038/s41422-021-00560-3. Online ahead of print Epub:
Yes Abstract:
Primary cilia extending from mother centrioles are essential for vertebrate development and homeostasis maintenance. Centriolar... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S. NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis. Cell Res. 2021 Sep 3. doi: 10.1038/s41422-021-00560-3. Online ahead of print. |
A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing
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Citation:
Cell Death Dis. 2021 Sep 6;12(9):838. doi: 10.1038/s41419-021-04130-8 Epub:
Not Epub Abstract:
Hereditary non-polyposis colorectal cancer, now known as Lynch syndrome (LS) is one of the most common cancer predisposition... Delivery Method:
electroporation, Vivo-Morpholino Organism or Cell Type:
cell culture: human and murine fibroblasts, mice Citation Extract: Biswas K, Couillard M, Cavallone L, Burkett S, Stauffer S, Martin BK, Southon E, Reid S, Plona TM, Baugher RN, Mellott SD, Pike KM, Albaugh ME, Maedler-Kron C, Hamel N, Tessarollo L, Marcus V, Foulkes WD, Sharan SK. A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing. Cell Death Dis. 2021 Sep 6;12(9):838. doi: 10.1038/s41419-021-04130-8. |
Function of chromatin modifier Hmgn1 during neural crest and craniofacial development
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Citation:
Genesis. 2021 Sep 3:e23447. doi: 10.1002/dvg.23447. Online ahead of print Epub:
Yes Abstract:
The neural crest is a dynamic embryonic structure that plays a major role in the formation of the vertebrate craniofacial... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Ihewulezi C, Saint-Jeannet JP. Function of chromatin modifier Hmgn1 during neural crest and craniofacial development. Genesis. 2021 Sep 3:e23447. doi: 10.1002/dvg.23447. Online ahead of print. |
Adar-mediated A-to-I editing is required for establishment of embryonic body axes in zebrafish
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.26.457081 Epub:
Not Epub Abstract:
Adenosine deaminases (ADARs) catalyze the deamination of adenosine to inosine, also known as A-to-I editing, in RNA. Although A... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Niescierowicz K, Pryszcz L, Navarrete C, Tralle E, Kasprzyk ME, Nahia KA, Misztal K, Bochtler M, Winata C. Adar-mediated A-to-I editing is required for establishment of embryonic body axes in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.26.457081. |
Loss of nucleoporin Nup50 is a risk factor for amyotrophic lateral sclerosis
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Citation:
medRxiv. 2021;[preprint] doi:10.1101/2021.08.23.21262299 Epub:
Not Epub Abstract:
The genetic basis of amyotrophic lateral sclerosis (ALS) is still incompletely understood. Using two independent genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Megat S, Mora N, Sanogo J, Catanese A, Alami NO, Freischmidt A, Mingaj X, de Calbiac H, Muratet F, Dirrig-Grosch S, Dieterle S, Van Bakel N, Müller K, Sieverding K, Weishaupt J, Andersen PM, Weber M, Neuwirth C, Margelisch M, Sommacal A, van Eijk KR, Veldink JH, Project Mine ALS sequencing consortium, Lautrette G, Couratier P, Boeckers T, Albert C. Ludolph AC, Roselli F, Yilmazer-Hanke D, Millecamps S, Kabashi E, Storkebaum E, Sellier C, Dupuis L. Loss of nucleoporin Nup50 is a risk factor for amyotrophic lateral sclerosis. medRxiv. 2021;[preprint] doi:10.1101/2021.08.23.21262299 . |
Neutrophil-associated responses to Vibrio cholerae infection in a natural host model
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.24.457598 Epub:
Not Epub Abstract:
Vibrio cholerae, the cause of human cholera, is an aquatic bacterium found in association with a variety of animals in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Farr D, Nag D, Chazin WJ, Harrison S, Thummel R, Luo X, Raychaudhuri S, Withey JH. Neutrophil-associated responses to Vibrio cholerae infection in a natural host model. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.24.457598. |
Foxm1 regulates neural progenitor fate during spinal cord regeneration
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Citation:
EMBO Rep. 2021:e50932. doi:10.15252/embr.202050932. Online ahead of print Epub:
Yes Abstract:
Xenopus tadpoles have the ability to regenerate their tails upon amputation. Although some of the molecular and cellular... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Pelzer D, Phipps LS, Thuret R, Gallardo-Dodd CJ, Baker SM, Dorey K. Foxm1 regulates neural progenitor fate during spinal cord regeneration. EMBO Rep. 2021:e50932. doi:10.15252/embr.202050932. Online ahead of print. |
The effect of absent blood flow on the zebrafish cerebral and trunk vasculature
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Citation:
Vascular Biol. 2021;(3)1:1-16. doi:10.1530/VB-21-0009 Epub:
Not Epub Abstract:
The role of blood flow in vascular development is complex and context-dependent. In this study, we quantify the effect of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kugler E, Snodgrass R, Bowley G, Plant K, Serbanovic-Canic J, Hamilton N, Evans PC, Chico T, Armitage P. The effect of absent blood flow on the zebrafish cerebral and trunk vasculature. Vascular Biol. 2021;(3)1:1-16. doi:10.1530/VB-21-0009. |
Structure-based design of antisense oligonucleotides that inhibit SARS-CoV-2 replication
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.23.457434 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) are an emerging class of drugs that target RNAs. Current ASO designs strictly follow the rule... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293-hACE2 Citation Extract: Li Y, Garcia G Jr, Arumugaswami V, Guo F. Structure-based design of antisense oligonucleotides that inhibit SARS-CoV-2 replication. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.23.457434. |