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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration
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Citation:
Biomedicines. 2019;7(2):30. doi:10.3390/biomedicines7020030 Epub:
Not Epub Abstract:
The Wnt pathway has been shown to regulate bone homeostasis and to influence some bone disease states. We utilized a zebrafish... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sarmah S, Curtis C, Mahin J, Farrell M, Engler TA, Sanchez-Felix MN, Sato M, Ma YL, Chu S, Marrs JA. The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration. Biomedicines. 2019;7(2):30. doi:10.3390/biomedicines7020030. |
Regardless of the deposition pathway, aminoacid 31 in histone variant H3 is essential at gastrulation in Xenopus
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Citation:
bioRxiv.2019;[preprint] doi:10.1101/612515 Epub:
Not Epub Abstract:
The closely related replicative H3 and non-replicative H3.3 variants show specific requirement during development in... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Sitbon D, Boyarchuk E, Almouzni G. Regardless of the deposition pathway, aminoacid 31 in histone variant H3 is essential at gastrulation in Xenopus. bioRxiv.2019;[preprint] doi:10.1101/612515. |
Coupling metastasis to pH sensing G Protein-coupled receptor-68 through first in class inhibitor identified in an in vivo chemical genetic screen
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Citation:
bioRxiv.2019;[preprint] doi:10.1101/612549 Epub:
Not Epub Abstract:
Acidic milieu is a hallmark of glycolytic metabolism which occurs in cancerous cells. The effect of the acidic environment on... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Williams CH, Thayer T, Wells Q, Wani M, Keyser B, Hong CC. Coupling metastasis to pH sensing G Protein-coupled receptor-68 through first in class inhibitor identified in an in vivo chemical genetic screen. bioRxiv.2019;[preprint] doi:10.1101/612549. |
QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis
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Citation:
PLoS ONE. 2019;14(4):e0215162. doi:10.1371/journal.pone.0215162 Epub:
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Dihydropteridine reductase (QDPR) catalyzes the recycling of tetrahydrobiopterin (BH4), a cofactor in dopamine, serotonin, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Breuer M, Guglielmi L, Zielonka M, Hemberger V, Kölker S, Okun JG, Hoffmann GF, Carl M, Sauer SW, Opladen T. QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis. PLoS ONE. 2019;14(4):e0215162. doi:10.1371/journal.pone.0215162. |
Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus
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Citation:
Sci Rep. 2019;9(1):6196. doi:10.1038/s41598-019-42549-4 Epub:
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Cerebrospinal fluid (CSF) flow in the brain ventricles is critical for brain development. Altered CSF flow dynamics have been... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Date P, Ackermann P, Furey C, Fink IB, Jonas S, Khokha MK, Kahle KT, Deniz E. Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus. Sci Rep. 2019;9(1):6196. doi:10.1038/s41598-019-42549-4. |
Mutations in ATP13A2 (PARK9) are associated with an amyotrophic lateral sclerosis-like phenotype, implicating this locus in further phenotypic expansion
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Citation:
Hum Genomics. 2019;13:19. doi:10.1186/s40246-019-0203-9 Epub:
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Background: Amyotrophic lateral sclerosis [1] is a genetically heterogeneous neurodegenerative disorder, characterized by late-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Spataro R, Kousi M, Farhan SMK, Willer JR, Ross JP, Patrick A. Dion PA, Rouleau GA, Daly, Neale BM, La Bella V, Katsanis N. Mutations in ATP13A2 (PARK9) are associated with an amyotrophic lateral sclerosis-like phenotype, implicating this locus in further phenotypic expansion. Hum Genomics. 2019;13:19. doi:10.1186/s40246-019-0203-9. |
Horizontal Boundary Cells, a Special Group of Somitic Cells, Play Crucial Roles in the Formation of Dorsoventral Compartments in Teleost Somite
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Citation:
Cell Rep. 2019;27(3):928-39.E4. doi:10.1016/j.celrep.2019.03.068 Epub:
Not Epub Abstract:
Establishment of robust gene expression boundary is crucial for creating elaborate morphology during development. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Abe K, Shimada A, Tayama S, Nishikawa H, Kaneko T, Tsuda S, Karaiwa A, Matsui T, Ishitani T, Takeda H. Horizontal Boundary Cells, a Special Group of Somitic Cells, Play Crucial Roles in the Formation of Dorsoventral Compartments in Teleost Somite. Cell Rep. 2019;27(3):928-39.E4. doi:10.1016/j.celrep.2019.03.068. |
The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish
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Citation:
Development. 2019;[Epub ahead of print] doi:10.1242/dev.171207 Epub:
Yes Abstract:
Tissue morphogenesis requires changes in cell-cell adhesion as well as in cell shape and polarity. Cardiac trabeculation is a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jiménez-Amilburu V, Stainier DYR. The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish. Development. 2019;[Epub ahead of print] doi:10.1242/dev.171207. |
Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis
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Citation:
Front Physiol. 2019;10:431 doi:10.3389/fphys.2019.00431 Epub:
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Wolf-Hirschhorn Syndrome (WHS) is a human developmental disorder arising from a hemizygous perturbation, typically a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mills A, Bearce E, Cella R, Kim SW, Selig M, Lee S, Lowery LA. Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis. Front Physiol. 2019;10:431 doi:10.3389/fphys.2019.00431. |
Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development
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Citation:
Blood Adv. 2019;3:1244-54. doi:10.1182/bloodadvances.2018024539 Epub:
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Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM. Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development. Blood Adv. 2019;3:1244-54. doi:10.1182/bloodadvances.2018024539. |