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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Partial uniparental isodisomy of chromosome 16 unmasks a deleterious biallelic mutation in IFT140 that causes Mainzer-Saldino syndrome

Authors:
Helm BM, Willer JR, Sadeghpour A, Golzio C, Crouch E, Vergano SS, Katsanis N, Davis EE
Citation:
Hum Genomics. 2017 Jul 19;11(1):16. doi: 10.1186/s40246-017-0111-9
Epub:
Not Epub
Abstract:
BACKGROUND: The ciliopathies represent an umbrella group of >50 clinical entities that share both clinical features and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Helm BM, Willer JR, Sadeghpour A, Golzio C, Crouch E, Vergano SS, Katsanis N, Davis EE. Partial uniparental isodisomy of chromosome 16 unmasks a deleterious biallelic mutation in IFT140 that causes Mainzer-Saldino syndrome. Hum Genomics. 2017 Jul 19;11(1):16. doi: 10.1186/s40246-017-0111-9.

The Role of the Wnt/PCP Formin Daam1 in Renal Ciliogenesis

Authors:
Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/512533
Epub:
Not Epub
Abstract:
Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK. The Role of the Wnt/PCP Formin Daam1 in Renal Ciliogenesis. bioRxiv. 2019;[Preprint] doi:10.1101/512533 .

Dual regulation of lin28a by Myc is necessary during zebrafish retina regeneration

Authors:
Mitra S, Sharma P, Kaur S, Khursheed MA, Gupta S, Chaudhary M, Kurup AJ, Ramachandran R
Citation:
J Cell Biol. 2019 Jan 3. pii: jcb.201802113. doi: 10.1083/jcb.201802113. [Epub ahead of print]
Epub:
Yes
Abstract:
Cellular reprogramming leading to induction of Muller glia-derived progenitor cells (MGPCs) with stem cell characteristics is...
Delivery Method:
injection and electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Mitra S, Sharma P, Kaur S, Khursheed MA, Gupta S, Chaudhary M, Kurup AJ, Ramachandran R. Dual regulation of lin28a by Myc is necessary during zebrafish retina regeneration. J Cell Biol. 2019 Jan 3. pii: jcb.201802113. doi: 10.1083/jcb.201802113. [Epub ahead of print].

Methods of Calpain Inhibition to Determine the Role of Calpains in Embryo Development in Amphibians

Authors:
Antoniades I, Charalambous A, Christodoulou N, Zanardelli S, Skourides PA
Citation:
Methods Mol Biol. 2019;1915:249-259. doi: 10.1007/978-1-4939-8988-1_19
Epub:
Not Epub
Abstract:
Calpains are a family of calcium-dependent intracellular cysteine proteases that regulate important physiological processes by...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Antoniades I, Charalambous A, Christodoulou N, Zanardelli S, Skourides PA. Methods of Calpain Inhibition to Determine the Role of Calpains in Embryo Development in Amphibians. Methods Mol Biol. 2019;1915:249-259. doi: 10.1007/978-1-4939-8988-1_19.

Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers

Authors:
Suzuki N, Hirano K, Ogino H, Ochi H
Citation:
eLife. 2019;8:e43186 doi:10.7554/eLife.43186
Epub:
Not Epub
Abstract:
Amphibians and fish have the ability to regenerate numerous tissues, whereas mammals have a limited regenerative capacity....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Suzuki N, Hirano K, Ogino H, Ochi H. Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers. eLife. 2019;8:e43186 doi:10.7554/eLife.43186.

Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development

Authors:
Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM
Citation:
bioRxiv. 2018:[Preprint] doi:10.1101/508531
Epub:
Not Epub
Abstract:
Erythropoiesis is the process by which new red blood cells (RBCs) are formed and defects in this process can lead to anemia or...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM. Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development. bioRxiv. 2018:[Preprint] doi:10.1101/508531.

Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation

Authors:
Korecka JA, Talbot S, Osborn TM, de Leeuw SM, Levy SA, Ferrari EJ, Moskites A, Atkinson E, Jodelka FM, Hinrich AJ, Hastings ML, Woolf CJ, Hallett PJ, Isacson O
Citation:
Stem Cell Reports. 2018 Dec 14. pii: S2213-6711(18)30490-9. doi: 10.1016/j.stemcr.2018.11.021. [Epub ahead of print]
Epub:
Yes
Abstract:
The Parkinson disease (PD) genetic LRRK2 gain-of-function mutations may relate to the ER pathological changes seen in PD...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human Parkinson's Disease iPSC-derived neurons
Citation Extract:
Korecka JA, Talbot S, Osborn TM, de Leeuw SM, Levy SA, Ferrari EJ, Moskites A, Atkinson E, Jodelka FM, Hinrich AJ, Hastings ML, Woolf CJ, Hallett PJ, Isacson O. Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation. Stem Cell Reports. 2018 Dec 14. pii: S2213-6711(18)30490-9. doi: 10.1016/j.stemcr.2018.11.021. [Epub ahead of print].

FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence

Authors:
Latorre E, Ostler EL, Faragher RGA, Harries LW
Citation:
FASEB J. 2019 Jan;33(1):1086-1097. doi: 10.1096/fj.201801154R. Epub 2018 Aug 8
Epub:
Not Epub
Abstract:
Cellular plasticity is a key facet of cellular homeostasis requiring correct temporal and spatial patterns of alternative...
Organism or Cell Type:
cell culture: senescent primary human fibroblasts
Citation Extract:
Latorre E, Ostler EL, Faragher RGA, Harries LW. FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence. FASEB J. 2019 Jan;33(1):1086-1097. doi: 10.1096/fj.201801154R. Epub 2018 Aug 8.

Blastemal progenitors modulate immune signaling during early limb regeneration

Authors:
Tsai SL, Baselga-Garriga C, Melton DA
Citation:
Development. 2019 Jan 2;146(1). pii: dev169128. doi: 10.1242/dev.169128
Epub:
Not Epub
Abstract:
Blastema formation, a hallmark of limb regeneration, requires proliferation and migration of progenitors to the amputation...
Delivery Method:
injection
Organism or Cell Type:
Ambystoma mexicanum (axolotl)
Citation Extract:
Tsai SL, Baselga-Garriga C, Melton DA. Blastemal progenitors modulate immune signaling during early limb regeneration. Development. 2019 Jan 2;146(1). pii: dev169128. doi: 10.1242/dev.169128.

Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies

Authors:
Khan TN, Khan K, Sadeghpour A, Reynolds H, Perilla Y, McDonald MT, Gallentine WB, Baig SM; Task Force for Neonatal Genomics, Davis EE, Katsanis N
Citation:
Am J Hum Genet. 2019 Jan 3;104(1):94-111. doi: 10.1016/j.ajhg.2018.11.017
Epub:
Not Epub
Abstract:
The use of whole-exome and whole-genome sequencing has been a catalyst for a genotype-first approach to diagnostics. Under this...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khan TN, Khan K, Sadeghpour A, Reynolds H, Perilla Y, McDonald MT, Gallentine WB, Baig SM; Task Force for Neonatal Genomics, Davis EE, Katsanis N. Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies. Am J Hum Genet. 2019 Jan 3;104(1):94-111. doi: 10.1016/j.ajhg.2018.11.017.

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