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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits
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Citation:
PLoS One. 2019 Jan 29;14(1):e0211073. doi: 10.1371/journal.pone.0211073. eCollection 2019 Epub:
Not Epub Abstract:
Through forward genetic screening for mutations affecting visual system development, we identified prominent coloboma and cell-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Turner KJ, Hoyle J, Valdivia LE, Cerveny KL, Hart W, Mangoli M, Geisler R, Rees M, Houart C, Poole RJ, Wilson SW, Gestri G. Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits. PLoS One. 2019 Jan 29;14(1):e0211073. doi: 10.1371/journal.pone.0211073. eCollection 2019. |
ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development
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Citation:
Nucleic Acids Res. 2019 Jan 30. doi: 10.1093/nar/gkz010. [Epub ahead of print] Epub:
Yes Abstract:
Stress hormones bind and activate the glucocorticoid receptor (GR) in many tissues including the brain. We identified arginine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, Hughes TR, Morris QD, Scott MS, Krause H, Angers S, Blencowe BJ, Cummins CL. ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Res. 2019 Jan 30. doi: 10.1093/nar/gkz010. [Epub ahead of print]. |
Analysis of cilia dysfunction phenotypes in zebrafish embryos depleted of Origin recognition complex factors
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Citation:
Eur J Hum Genet. 2019 Jan 29. doi: 10.1038/s41431-019-0338-0. [Epub ahead of print] Epub:
Yes Abstract:
Meier-Gorlin syndrome (MGS) is a rare, congenital primordial microcephalic dwarfism disorder. MGS is caused by genetic variants... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Maerz LD, Casar Tena T, Gerhards J, Donow C, Jeggo PA, Philipp M. Analysis of cilia dysfunction phenotypes in zebrafish embryos depleted of Origin recognition complex factors. Eur J Hum Genet. 2019 Jan 29. doi: 10.1038/s41431-019-0338-0. [Epub ahead of print]. |
CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection
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Citation:
Hum Mol Genet. 2019 Jan 26. doi: 10.1093/hmg/ddz029. [Epub ahead of print] Epub:
Yes Abstract:
High myopia is a severe form of nearsightedness, which can result in blindness due to its associated complications. While both... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ouyang J, Sun W, Xiao X, Li S, Jia X, Zhou L, Wang P, Zhang Q. CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection. Hum Mol Genet. 2019 Jan 26. doi: 10.1093/hmg/ddz029. [Epub ahead of print]. |
Morpholino-Mediated Gene knockdown in Zebrafish: It's All About Dosage and Validation
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Citation:
J Invest Dermatol. 2019 Jan 29. pii: S0022-202X(19)30042-9. doi: 10.1016/j.jid.2019.01.017. [Epub ahead of print] Epub:
Yes Abstract:
No abstract available
(Letter to the Editor)
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Van Gils M, Vanakker OM. Morpholino-Mediated Gene knockdown in Zebrafish: It's All About Dosage and Validation. J Invest Dermatol. 2019 Jan 29. pii: S0022-202X(19)30042-9. doi: 10.1016/j.jid.2019.01.017. [Epub ahead of print] . |
Intelectin 3 is dispensable for resistance against a mycobacterial infection in zebrafish (Danio rerio)
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Citation:
Sci Rep. 2019 Jan 30;9(1):995. doi: 10.1038/s41598-018-37678-1 Epub:
Not Epub Abstract:
Tuberculosis is a multifactorial bacterial disease, which can be modeled in the zebrafish (Danio rerio). Abdominal cavity... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ojanen MJT, Uusi-Mäkelä MIE, Harjula SE, Saralahti AK, Oksanen KE, Kähkönen N, Määttä JAE, Hytönen VP, Pesu M, Rämet M. Intelectin 3 is dispensable for resistance against a mycobacterial infection in zebrafish (Danio rerio). Sci Rep. 2019 Jan 30;9(1):995. doi: 10.1038/s41598-018-37678-1. |
Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport
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Citation:
Nat Commun. 2019 Jan 25;10(1):428. doi: 10.1038/s41467-018-08192-9 Epub:
Not Epub Abstract:
The intracellular ciliogenesis pathway requires membrane trafficking, fusion, and reorganization. Here, we demonstrate in human... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Insinna C, Lu Q, Teixeira I, Harned A, Semler EM, Stauffer J, Magidson V, Tiwari A, Kenworthy AK, Narayan K, Westlake CJ. Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. Nat Commun. 2019 Jan 25;10(1):428. doi: 10.1038/s41467-018-08192-9. |
Venous identity requires BMP signalling through ALK3
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Citation:
Nat Comm. 2019;10:453. doi:doi.org/10.1038/s41467-019-08315-w Epub:
Not Epub Abstract:
Venous endothelial cells are molecularly and functionally distinct from their arterial counterparts. Although veins are often... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Neal A, Nornes S, Payne S, Wallace MD, Fritzsche M, Louphrasitthiphol P, Wilkinson RN, Chouliaras KM, Liu K, Plant K, Sholapurkar R, Ratnayaka I, Herzog W, Bond G, Chico T, Bou-Gharios G, De Val S. Venous identity requires BMP signalling through ALK3. Nat Comm. 2019;10:453. doi:doi.org/10.1038/s41467-019-08315-w. |
Scavenger receptor class A1 mediates uptake of morpholino antisense oligonucleotide into dystrophic skeletal muscle
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Citation:
Mol Ther Nucl Acids. 2019 Jan 25;14:520-535. doi: 10.1016/j.omtn.2019.01.008. Epub:
Not Epub Abstract:
Exon-skipping using phosphorodiamidate morpholino oligomers (PMOs) is a promising treatment strategy for Duchenne muscular... Delivery Method:
peptide-linked, cell bathing Organism or Cell Type:
mice mdx62, cell culture: H2K-mdx 52 myoblasts Citation Extract: Miyatake S, Mizobe Y, Tsoumpra M, Lim KRQ, Hara Y, Shabanpoor F, Yokota T, Takeda S, Aoki Y. Scavenger receptor class A1 mediates uptake of morpholino antisense oligonucleotide into dystrophic skeletal muscle. Mol Ther Nucl Acids. 2019 Jan 25;14:520-535. doi: 10.1016/j.omtn.2019.01.008. . |
Photoreceptor cell development requires prostaglandin signaling in the zebrafish retina
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Citation:
Biochem Biophys Res Commun. 2019 Jan 24. pii: S0006-291X(19)30087-7. doi: 10.1016/j.bbrc.2019.01.073. [Epub ahead of print] Epub:
Yes Abstract:
Photoreceptor cells are highly specialized sensory neurons capable of visual phototransduction. The connecting cilia in the... Organism or Cell Type:
zebrafish Citation Extract: Li W, Jin D, Zhong TP. Photoreceptor cell development requires prostaglandin signaling in the zebrafish retina. Biochem Biophys Res Commun. 2019 Jan 24. pii: S0006-291X(19)30087-7. doi: 10.1016/j.bbrc.2019.01.073. [Epub ahead of print]. |